Montagne Lab
@MontagneLab
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Montagne lab @EdinburghUni @UKDRI. We 🇲🇽🇸🇰🇺🇸🇬🇧🇭🇺🇨🇿🇨🇴🇮🇪🇪🇸🇪🇨🇦🇺🇫🇷🇲🇴 study the cerebrovasculature in health and disease.
Edinburgh
Joined April 2021
RT @AkassoglouLab: The first patient in Phase 1b trial for Alzheimer's disease has been dosed with the fibrin-targeting immunotherapy. I am….
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RT @AxL_Montagne: 🚨 Review Alert. *Walking on the tightrope: the shared roles of the bridging pericytes in the brain*. Congratulations Audr….
frontiersin.org
The vasculature of the central nervous system (CNS) is a highly specialized structure that delivers oxygen and nutrients to energy-demanding neural cells whi...
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RT @AxL_Montagne: Well done @DanyJaimeGarcia 👏🤩. Blood biomarkers of vascular dysfunction in small vessel disease progression: Insights fro….
alz-journals.onlinelibrary.wiley.com
INTRODUCTION This study explored the relationship between blood biomarkers of cerebrovascular function and small vessel disease (SVD) neuroimaging markers and cognitive outcomes in highly-phenotype...
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RT @HAT_Pritchard: We have a @TheBHF funded postdoc position to work on a novel treatment option to improve cerebral blood flow in a model….
jobs.manchester.ac.uk
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RT @Andy_P_Tsai: Another @wysscoray & @StephenQuake labs collaboration! 🔬 With @HenzeDoug, we identify a subtype of disease-associated micr….
biorxiv.org
Cellular morphology is intimately connected with function. While the link between morphology and functional states has been studied extensively, the role of subcellular transcript localization in...
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RT @UKDRI: Fascinating new research by @adrianisaacslab reveals that enhancing levels of “healthy fats” like omega-3s in the brain could be….
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A lovely team of brilliant minds!.
Shoutout to an amazing team - great science is only possible because of great people! 😍
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RT @UKDRI: We are excited to begin our international search for a new Centre Director at the UK DRI at Cardiff University! 🏴 . Help s….
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RT @AxL_Montagne: 🚨 Check out our latest contribution where we delve into the dementia-related snRNA-seq data and spotlight the signature c….
alz-journals.onlinelibrary.wiley.com
INTRODUCTION Cerebrovascular dysfunction plays a critical role in the pathogenesis of dementia and related neurodegenerative disorders. Recent omics-driven research has revealed associations betwee...
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RT @PedronSwannie: Impressive lab work from @MontagneLab presented this morning in front of all @BbCaen team. Thank you @AxL_Montagne for s….
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RT @AxL_Montagne: Interested in pursuing a PhD with @dickie_ben, @HAT_Pritchard, and me to explore the role of mural cells in Alzheimer’s d….
findaphd.com
PhD Project - (VIDA DTC) Role of arterial smooth muscle and pericyte dysfunction towards brain waste clearance in Alzheimer’s Disease at The University of Manchester, listed on FindAPhD.com
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RT @HaselPhilip: PhD opportunity: If you're interested in how astrocytes and the meninges talk to each other and how this is affected in de….
findaphd.com
PhD Project - (VIDA DTC) Exploring the role of the astrocyte-leptomeningeal vessel interface in dementia at University of Edinburgh, listed on FindAPhD.com
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RT @Conasaurus1: Very lucky to get to talk about our research in the #vascular at this year's ECaT day @UKDRI @UKDRI_ECR #connectome2024 .….
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RT @UKDRI: 🗳️ Cast your vote! 🗳️ . With the UK DRI’s conference ‘Connectome’ just around the corner, we need your help selecting the winner….
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RT @caromenard666: So excited to share the PhD work 👶 of Laurence @cLAUdin5_ exploring how #pericyte function modulate 🧠 #stress responses….
researchsquare.com
Major depressive disorder (MDD) is a leading cause of disease burden worldwide with low therapeutic efficacy. The blood-brain barrier (BBB) is essential to maintain brain homeostasis and regulate...
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RT @UKDRI: Prof Joanna Wardlaw is setting up the first phase 3 trial in cerebral small vessel disease aimed at improving cognitive symptoms….
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RT @AxL_Montagne: Inhibiting Ca2+ channels in Alzheimer’s disease model mice relaxes pericytes, improves cerebral blood flow and reduces im….
nature.com
Nature Neuroscience - Early in Alzheimer’s disease (AD), brain blood flow is reduced by pericytes constricting capillaries. Korte et al. show that oral nimodipine can reverse this and...
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