Some personal updates: Defended my PhD in Neuroscience @OttawaCmm, I had a blast working on serotonergic circuitry, synapses, and population coding with @JCBeique and @NeuroNaud. Arrived in Oxford, UK last month to start a postdoc with @ArminLak! Excited for next steps!.

RT @toschi_chiara: cool survey going around by a team of fellow neuroscientists on research and publishing dynamics in neuroscience, if you….

Come check out our poster on neuropixels, perception and cortical/subcortical routing (F17) at @SfNtweets led by the supremely talented @NeuroRussell with @ArminLak @paqio

RT @NeuroRussell: If you are at @SfNtweets, check out my poster tomorrow AM on my PhD work so far with the brilliant @MichaelBLynn_ and @Ar….

RT @ArminLak:

RT @ArminLak: Three days of brainstorming, useful discussions, team building & fun with amazing lab members. In vivo daily experiments and….

RT @OcanaSantero: At #FENS2024? Check poster 37 on Saturday to see how genetics, antidepressants and aversive experience shape developmenta….

RT @NeuroNaud: What regulates serotonin release? Michael mapped out the salient network mechanisms and release dynamics:.

RT @ivanalexlazarte: Interested in claustrum, amygdala, pfc, circuit mapping or just the brain? Check out my poster (499) this afternoon at….

And thanks to @JCBeique and @NeuroNaud for ideas and supervision - a great experimental/computational collab!.

@yulonglilab Check out the original tweeprint if you want to learn more about our original findings!.

@yulonglilab Overall these new results are exciting for us because they more rigorously explore this unsuspected slow serotonergic recurrent inhibitory network in the raphe, as well as pinpointing a set of robust, core computations that it supports.

@yulonglilab We also conducted new comparisons between recurrent inhibition and classical GABAergic feedforward inhibition in raphe, showing the latter appears to be much weaker than recurrence under our preparation

@yulonglilab Winner-take-all dynamics between subnetworks were likewise robust to network parameters, like spatial connectivity profiles and input overlap, thanks to this normalizing property of short-term recurrent facilitation.

@yulonglilab Extensive new computational simulations demonstrated a surprising feature of synaptic facilitation: it allows network activity to track input frequency while normalizing for precise connectivity details (like the fraction of 5-HT neurons receiving an input).

We directly measured serotonin signals in raphe using GRAB5-HT sensors from @yulonglilab, revealing strong synaptic facilitation dynamics and a characteristic spatial structures of serotonin release (hotspots) that scale with frequency

With new tracer experiments, we’ve been able to map the spatial scale of recurrence in DRN, showing these connections can span almost the entire DRN, and hinting at submodule-specific differences in connectivity rules

Excited to share our updated preprint characterizing a novel, slow recurrent circuit motif in raphe!.

RT @NeuroRussell: If you are attending @FENSorg today, check out my poster on my PhD work so far with the brilliant @MichaelBLynn_ and @Arm….

RT @ArminLak: Heading to #FENS2024, check out our lab posters; all data shown 1st time; all on cortex -> striatum <- DA/Ach.

Check out our FENS poster on perceptual signals in subcortical networks, led by fantastic DPhil student @NeuroRussell!.