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Jörg Menche Profile
Jörg Menche

@MencheLab

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Vienna, Austria
Joined April 2018
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@MencheLab
Jörg Menche
3 years
Interested in network visualizations that are not just pretty, but actually mean something? Check out our new paper @NatComputSci: .@CeMM_News @MaxPerutzLabs @univienna (1/n).
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@MencheLab
Jörg Menche
3 years
Finally, we would like to thank our host institutions @MaxPerutzLabs, @univienna and @CeMM_News, and of course the @WWTF for funding. (n/n).
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@MencheLab
Jörg Menche
3 years
All credits go to the amazing @ChrisHuetter who made it all happen. Originally trained in architecture, she dared to embark on an entirely different adventure with us on this project. This is her explaining it herself: (10/n).
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@MencheLab
Jörg Menche
3 years
I hope that the wide #NetSci and #dataviz community will find our method as useful as I do. All our code is public and there’s also a little webtool (9/n).
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@MencheLab
Jörg Menche
3 years
Our method can be used both to explore unknown network characteristics, as well as to accurately depict known ones. For example, I struggled for years to visually depict disease modules in the interactome. This can finally be done systematically!.(8/n)
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@MencheLab
Jörg Menche
3 years
Finally, we would like to thank our host institutions @MaxPerutzLabs, @univienna and @CeMM_News, and of course the @WWTF for funding. (n/n).
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@MencheLab
Jörg Menche
3 years
(n+1 / n) I should use twitter more often, I still don't know how threads work 🙄.
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@MencheLab
Jörg Menche
3 years
All credits go to the amazing @ChrisHuetter who made it all happen. Originally trained in architecture, she dared to embark on an entirely different adventure with us on this project. This is her explaining it herself: (10/n).
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@MencheLab
Jörg Menche
3 years
I hope that the wide #NetSci and #dataviz community will find our method as useful as I do. All our code is public and there’s also a little webtool (9/n).
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@MencheLab
Jörg Menche
3 years
Our method can be used both to explore unknown network characteristics, as well as to accurately depict known ones. For example, I struggled for years to visually depict disease modules in the interactome. This can finally be done systematically!.(8/n).
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@MencheLab
Jörg Menche
3 years
We propose a series of layouts emphasizing various network characteristics that can be structural (e.g. node centrality), but also functional. One can choose pretty much anything. And since we know exactly what the node positions mean, we can finally interpret the layouts. (7/n)
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@MencheLab
Jörg Menche
3 years
We use a pretty simple trick allowing us to directly encode any quantity we like into node positions: dimensionality reduction! There are widely used algorithms for this, they are fast and can map anything onto various 2D and 3D geometries. (6/n)
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@MencheLab
Jörg Menche
3 years
#2 Interpretability. In conventional layout algorithms, it’s often hard to tell what exactly is driving the position of a node (see Mark Newman above!). Our work offers a solution to this. (5/n).
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@MencheLab
Jörg Menche
3 years
#1 Size. The space on a computer screen or a piece of paper is just very limited. Displaying large networks will always be tough there. Not so in Virtual Reality, where you can blow a network up to the size of a cathedral and be right in the middle. (4/n)
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@MencheLab
Jörg Menche
3 years
At the same time, networks provide a super intuitive visual representation for often very complicated data. So how can we defeat the hairball and leverage the full power of network visualizations? I think the solution has two key aspects:.(3/n).
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@MencheLab
Jörg Menche
3 years
I am particularly fond of this work, as it offers a solution to a problem that has been bugging me since my PhD: The hairball! Mark Newman put it perfectly in his classic review:.(2/n)
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@MencheLab
Jörg Menche
4 years
RT @CeMM_News: CeMM Adjunct PI Jörg Menche (@MencheLab / @MaxPerutzLabs / @univienna) & his team have developed a multiplex #network that w….
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@MencheLab
Jörg Menche
4 years
Finally, we would like to thank our collaborators for joining us on this adventure! We couldn’t have done it without Vanja and her team from the @Lab_Nagy. We are also grateful to our fantastic institutions @CeMM_News @MaxPerutzLabs and funding agency @WWTF (n/n).
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@MencheLab
Jörg Menche
4 years
All credits go to the amazing @izebuphamalai who performed this extensive tour de force of crunching dozens of datasets, extracting millions of interactions, thousands of diseases … This is what we looked like when we finally submitted the paper (10/n)
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@MencheLab
Jörg Menche
4 years
More generally, our approach represents a network-based strategy for identifying and integrating the most relevant datasets for a particular biological application. (9/n).
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