Marcus Pinto, MD, MS
@MarcusVPinto
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Peripheral Nerve Neurologist and Pathologist @MayoClinic. Check my Highlights for Peripheral Neuropathy Education.
Rochester, MN
Joined June 2019
In this case-control study of patients with diabetes, we show that GLP1 receptor agonists increase the risk of diabetic lumbosacral radiculoplexus neuropathy (diabetic amyotrophy) in 51% and peroneal mononeuropathy in 30% compared to controls @GreenJournal
neurology.org
Background and ObjectivesGlucagon-like peptide-1 receptor agonists (GLP-1RAs) are increasingly used to treat obesity and diabetes. Semaglutide, a GLP-1RA, is linked to nonarteritic ischemic optic...
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RT @EidSteph: Had a wonderful time visiting the @UT_Dallas @UTDPainCenter ! Huge thanks to @dianatavf for the warm welcome and to everyone….
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RT @Neurodiab_eu: The triglyceride-glucose index as a predictor of cardiovascular autonomic neuropathy in the ACCORD study.On Neurodiab we….
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RT @MarcusVPinto: What makes a distal symmetric polyneuropathy severe?. An internal medicine doctor asked me this question here on @X , and….
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RT @EWijdicks: You can prepare for one of the most consequential specialties in your discipline (with support from Oxford University Press)….
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They also asked when I order a nerve biopsy in DSP. I rarely biopsy DSP. I discuss about when to order a nerve biopsy in this @AANEMorg podcast.
You should listen to this podcast if you don't know when to order a nerve or muscle biopsy! Dr. Shaibani and I discuss the role of muscle and nerve biopsies in neuromuscular disorders. Thank you very much, @AANEMorg, for the invitation!. #NeuropathyBites.
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I define DSP as a sensory predominant neuropathy, that can also have motor involvement, is distal predominant, and worsens in an ascending length-dependent fashion: foot->leg-> hands/knee->elbow/anterior abdomen. Check out my post about neuropathy clinical phenotypes.
When I have a new fellow or resident in our peripheral nerve clinic, I always teach them the importance of defining the neuropathy clinical syndrome. NCS/EMG are valuable, but the neurological exam is the most important (as it should be in neurology but many have forgotten).
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Of course, these only count if caused by the polyneuropathy. History of falls, use of gait aids, and disequilibrium are also typical indicators of severe DSP. However, I prefer not to rely solely on history to assess the severity of a polyneuropathy, as functional overlay is.
Chronic idiopathic axonal polyneuropathy (CIAP) is the most common “etiology” of distal symmetric polyneuropathy after diabetic neuropathy. However, CIAP is very unlikely to be the cause if any of the following are present:. 1. Foot drop.2. Marked.
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What makes a distal symmetric polyneuropathy severe?. An internal medicine doctor asked me this question here on @X , and I share below simple features that indicate a severe DSP if present (any). Neurological exam: sensory ataxia, foot drop, hand weakness (in the absence of
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This is one of the reasons I’ve started posting here and will keep doing so. I can’t help all the patients I want to help only at my clinic. My research and review papers undergo peer review, and I’m rarely able to fully express my opinion there. Also, there’s no easier way for.
@DilipMysore @nihardesai89 First case of POEMS in the college. Diagnosed by a resident. The case was presented at a national conference of neurology and even they did not accept it. So I asked @MarcusVPinto to review the case and he agrees. LOL.
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RT @aszelikovich: Is #neurology 🧠 becoming more competitive for residency?? . Thanks to @AANmember work on developing the pipeline, in 2025….
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RT @HooshmandSam: Rare disease spotlight: Largest study of anti-AMPAR encephalitis. Distinct pediatric vs adult features, long-term outcome….
neurology.org
Background and ObjectivesAnti–alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor (anti-AMPAR) encephalitis manifests as limbic encephalitis in adults and is often associated with...
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RT @IsaacLamb01: We’ve seen a bunch of meningitis this week, so here are a few teaching points that have come up: . #neurology #MedEd #FOAM….
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RT @EliaSechi: In our recent study, the "Insular Knife Cut" Sign had 99.3% specificity for HSV encephalitis and was often detectable early….
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What I love most about practicing hospital neurology is working with residents and learning from complex cases. Neurology is humbling and fascinating. The hospital reminds me why I chose Neurology and helps me become a better neurologist for my subspecialty clinic patients. 🤓.
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RT @GreenJournal: Neurology Podcast: Dr. Trey Bateman and Dr. David T. Jones discuss how the StateViewer system leverages FDG-PET imaging a….
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RT @HooshmandSara: Check out our paper ⬇️. We propose improvements to the ADEM criteria to better capture MOGAD cerebral attacks . Why? ADE….
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RT @EoinFlanagan14: Excited to share @HooshmandSara et al study applying the #ADEM definition in #MOGAD that shows updated ADEM diagnostic….
journals.sagepub.com
Background: Acute disseminated encephalomyelitis (ADEM) is a demyelinating syndrome observed in myelin oligodendrocyte glycoprotein antibody-associated disease ...
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RT @jonstoneneuro: Our new open access paper looking at Migraine and FND, two of the commonest conditions in neurological practice. Migrai….
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RT @VincentRK: The one thing that helped my career was the wisdom of my internal medicine program director who said, you are good, and what….
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