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Manjula Kurella Tamura Profile
Manjula Kurella Tamura

@ManjulaKTamura

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Nephrologist | Advocate for Real-world Evidence

Palo Alto, CA
Joined December 2022
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@ManjulaKTamura
Manjula Kurella Tamura
8 months
RT @GeriPalBlog: #Dialysis vs Conservative Management for #OlderAdults: We discuss the pros/cons, effectiveness, tradeoffs, the need for mo….
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@ManjulaKTamura
Manjula Kurella Tamura
8 months
@StanfordNeph⁩ graduate student June Li mesmerizes the assembled crowd with her oral abstract from the RELATE consortium at #KidneyWk
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@ManjulaKTamura
Manjula Kurella Tamura
11 months
As the editorialists @SofiaAhmedMD and @VictoriaRiehlT noted, let’s do better for our patients and give them more choices for managing chronic kidney failure. (my first tweet thread - hope I did it right).
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@ManjulaKTamura
Manjula Kurella Tamura
11 months
I think these results, along with those of prior studies, are strong arguments that equipoise exists to test interventions like incremental dialysis start or responsive symptom management.
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@ManjulaKTamura
Manjula Kurella Tamura
11 months
Important caveat—like most observational studies on this topic, we don’t know if symptoms differed between the group who started dialysis and those who continued medical mgmt. Some might say we need a clinical trial to answer these questions. I agree!.
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@ManjulaKTamura
Manjula Kurella Tamura
11 months
those who started dialysis at this level of kidney function lived longer by 77 days, but they spent less time at home. The trade-offs between life expectancy and home time were more favorable for dialysis in groups who were older and had lower levels of kidney function.
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@ManjulaKTamura
Manjula Kurella Tamura
11 months
We found that older patients who start dialysis when eGFR <12 ml/min live longer by a week than those who continue medical mgmt and could start dialysis later, but they spend 2 weeks less at home. Compared to those who forego dialysis completely, . .
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@ManjulaKTamura
Manjula Kurella Tamura
11 months
To inform these decisions, we designed this target trial emulation study. @MontezRath.@vcharuMD.@DaceySeib.@ShipraAryaMD.@enricaf2.@annmohare.
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@ManjulaKTamura
Manjula Kurella Tamura
11 months
We’ve been discussing dialysis but he’s undecided. Should we start dialysis soon, should we wait until his symptoms or kidney function worsen, or should he forego dialysis completely?.
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@ManjulaKTamura
Manjula Kurella Tamura
11 months
He has cognitive impairment that is worse now, he’s experiencing fatigue, and his family says he’s not eating well – all symptoms that could be related to his kidney failure or other medical problems.
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@ManjulaKTamura
Manjula Kurella Tamura
11 months
In my advanced CKD clinic, this is a common clinical encounter: Mr. Jones is 83 and has chronic kidney failure with a low eGFR. He’s not eligible for a transplant.
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@ManjulaKTamura
Manjula Kurella Tamura
11 months
RT @MontezRath: Excited to share this important work with the community. Effect of Starting Dialysis Versus Continuing Medical Management….
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@ManjulaKTamura
Manjula Kurella Tamura
11 months
RT @GoStanford: There's the world, and then there's Stanford. If Stanford were its own country, it'd be tied for 11th in event medals at #….
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@ManjulaKTamura
Manjula Kurella Tamura
11 months
RT @JASN_News: SPRINT showed that intensive lowering of systolic BP increased the risk of incident CKD and episodes of AKI. A study looked….
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@ManjulaKTamura
Manjula Kurella Tamura
1 year
RT @rajmehrotra1122: Tune in to the first Kidney Translation podcast, the ASN journal portfolio podcast. Thank you….
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@ManjulaKTamura
Manjula Kurella Tamura
1 year
Excited to share work from @StanfordNeph @StanfordEpiNews PhD student June Li:. Representation of Real‐World Adults With Chronic Kidney Disease in Clinical Trials Supporting Blood Pressure Treatment Targets | Journal of the American Heart Association
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@ManjulaKTamura
Manjula Kurella Tamura
1 year
RT @Carmendemigue12: What a better way to celebrate Valentine's day than with a #HYPHIP chat about treatment of #HTN in veterans with Kidne….
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@ManjulaKTamura
Manjula Kurella Tamura
2 years
RT @JASN_News: Criteria to individualize glycemic targets in patients with type II diabetes are lacking. This study found heterogenous trea….
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@ManjulaKTamura
Manjula Kurella Tamura
2 years
There were broad-based changes in #htn practice patterns contributing to a decline in BP control among adults with #CKD between 2011 and 2015 (i.e. before JNC8 was released), including fewer prescriptions of first-line therapies. #KidneyinCVD.
@HyperAHA
Hypertension
2 years
In CKD adults treated in @DeptVetAffairs, BP control declined from 78%-71% from 2011-2015, then increased. #KidneyInCVD .@MontezRath @kingpaoman @enricaf @vcharumd @jaejin_an1 @JJSim008 @ManjulaKTamura @VAPaloAlto @KPSCalResearch @StanfordNeph @enricaf2.
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@ManjulaKTamura
Manjula Kurella Tamura
2 years
🙏 to the leadership of @rajmehrotra1122 @deboerih @ChoncholMichel and my @CJASN colleagues for the past 7 years, and so proud of what we’ve accomplished. Privileged to work with this amazing group.
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