MHR | Foundations of Reproductive Science
@MHR_ReprodSci
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MHR leads the way in research focused on the foundational and translational mechanisms of mammalian reproduction. @ESHRE @OUPAcademic @OxfordJournals
Joined May 2022
A comparative study of different 3D mouse in vitro #follicleculture methods reveals that the matrix-free non-attachment system is more efficient than complex encapsulation methodologies, sustaining high oocyte meiotic and developmental competence. #EditorChoice .Free to read🔗📚.
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In vitro follicle culture is an emerging #FertilityPreservation solution for women and children with cancer. Recent advances have yielded various 3D methods that preserve follicular structure. Which is the best? 🧐.
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“Early signaling pathways during in vitro culture of isolated primordial follicles”. Don’t miss this interesting piece investigating the main transcriptional events and molecular factors determining follicle fate 🧫🐮. Dive into the full article 🔗👇.
academic.oup.com
Abstract. The ability to grow undifferentiated oocytes in vitro from primordial follicles would increase the availability of fully grown oocytes in fertili
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🚨Save the date for the Symposium on the Paternal Origins of Health and Disease!. 🗓️October 16th, 2025.📍@InstitutCochin (Paris, France) and online.🔗Registration 👇👇.
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RT @Endometriosis: #EPHect today publishes SOPs to optimise use of experimental in vivo + in vitro models in #endometriosis research in @MH….
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Marr et al. discusses the use of #organoids as an emerging technology to study endometriosis, and the possibility to develop more complex organoid systems (assembloids) that reflect the interplay of multiple cell types in vivo.
academic.oup.com
Abstract. The aetiology of endometriosis remains poorly understood. In vitro model systems provide the opportunity to identify the mechanisms driving disea
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Dodds et al. examines the methods to assess #pain-associated behaviors in rodents models of endometriosis, and offers best practice recommendations for conducting such tests, aiming to improve study comparability.
academic.oup.com
Abstract. Pain is a debilitating symptom of endometriosis, and its mechanisms are often explored using rodent models. However, a lack of harmonization amon
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Hull te al. focuses on #heterologous rodent models. In this case, what can be standardized includes tissue placement, hormonal status, and housing conditions for mice with compromised immune system.
academic.oup.com
Abstract. Endometriosis, defined as the growth of endometrial-like tissues outside the uterus, is a common disease among women. Numerous in vivo rodent mod
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Burns et al. discusses the use of #homologous rodent models, which mainly consists of the intraperitoneal transplantation of uterine tissue, and the importance to define standardizing parameters, such as methods of induction and ectopic tissue placement.
academic.oup.com
Abstract. In vivo models of endometriosis enable the discovery and preclinical testing of new therapies. Several rodent models of endometriosis exist, but
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This remarkable initiative brings together 44 collaborators from 11 countries, resulting in the publication of 1 #Editorial and 4 #articles in the latest issue of Molecular Human Reproduction!!. @Endometriosis #WomensHealth .
academic.oup.com
Endometriosis affects an estimated >200 million women (and those assigned female at birth) during their most active and reproductive years, causing a hi
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RT @shiyan_tang: Huge shoutout to Dr. Olga Astapova (@female_dr_ ) for winning the very first HMR Early Career Innovator Award! 🏆🔥@MHR_Repr….
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🤩See you soon at the #MHRsymposium!!. 📍Session 53, Tuesday from 14:00-15:15. @OUPMedicine @OUPAcademic .@ESHRE.
✨The #ESHRE Annual Meeting 2025 is just around the corner!!. Join us at the #MHRsymposium where MHR’s Editor-in-Chief, @BoianiMichele, and Deputy Editor, Francesca Duncan @NUDuncanLab, will be hosting the session about Basic principles of ovarian function in vivo and in vitro.
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RT @BoianiMichele: In 2023, our group (Israel et al., Mol Hum Reprod @MHR_ReprodSci) showed that there is an intracellular fraction of zona….
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🤩ESHRE journals’ “Parisian cafe’” at #ESHRE2025!!. @OUPMedicine @ESHRE .#MHR #ESHREjournals #EarlyCareerInnovatorSeries
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Excited for #ESHRE2025 in Paris!!🤩.Join us at the Precongress Course 12:.“Academic authorship - Milestones in reproductive science: highlights from ESHRE Journals”.
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