Michael Pillinger
@MHPillingerMD
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Professor @NYULangone, rheumatologist, clinical researcher, lover of literature. Working on treatment of inflammation & COVID-19; US co-PI on #COLCORONA.
Joined January 2021
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#ColCorona published! (@LancetRespiriMed). For PCR+ #COVID19 outpatients, 0.5 mg daily colchicine reduced hospitalization/pneumonia. Among select populations, NNT was around 30. For the right patients, colchicine is cheap, safe and could save resources and potentially lives.
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RT @BinitaShahMD: ColCorona data are online. Still under peer review though! Consideration for early intervention with colchicine if COVID….
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Agree completely! I encourage everyone to wait for our paper (coming soon) before drawing conclusions.
A gout drug shows promise for Covid-19, but skeptics worry about trusting science by press release via @statnews.
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Smart idea @ashira_md! Our past research shows colchicine inhibits neutrophil-platelet but not platelet-platelet aggregation. But we hypothesize that inflammasome inhibition may be at least equally important here.
@LCalabreseDO @jasonsknight Publication is on the way! @MHPillingerMD and @BinitaShahMD coordinated the NYU site! Very exciting news, I wonder if a neutrophil-centered strategy blocked netosis and therefore platelet aggregation. Can’t wait for the full results!.
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