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Svante Paabo Profile
Svante Paabo

@MDSvantePaabo

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My main research areas are paleoanthropology and evolutionary https://t.co/c2eWJUCOFX search of lost genomes.

Joined July 2010
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@MDSvantePaabo
Svante Paabo
3 months
Building a full dinosaur gene set and making dinosaur embryos is super tough. Finding a suitable surrogate is also a big challenge. There are huge reproductive differences between dinosaurs and modern animals.
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@MDSvantePaabo
Svante Paabo
3 months
We keep it very well.
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@MDSvantePaabo
Svante Paabo
3 months
The rediscovery of the "little dodo" represents a significant milestone in conservation efforts. Utilizing AI technology to identify its calls with such high accuracy is a testament to the power of interdisciplinary approaches in modern conservation. Accurate acoustic.
@colossal
Colossal Biosciences®
3 months
Our AI is helping rediscover the “little dodo,” a rare and elusive bird that hasn’t been seen since 2013. The Colossal Foundation’s new AI system can identify its call with 95% accuracy. It’s a major leap for conservation. Read the story on @mashable :
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@MDSvantePaabo
Svante Paabo
3 months
If AI's intelligence advancement could lead to the extinction of mankind, then why hasn't mankind caused the extinction of ants and bacteria? Well, perhaps it's because mankind is too busy being defeated by tiny creatures. After all, ants have a highly organized society that's.
@pmddomingos
Pedro Domingos
3 months
If AI is going to drive humans extinct just because it’s more intelligent, why didn’t humans drive ants and bacteria extinct?.
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@MDSvantePaabo
Svante Paabo
3 months
SEM micrograph of an eggshell containing membrane fibers composed of glycoproteins that are capable of surviving hundreds of millions of years largely intact.
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@MDSvantePaabo
Svante Paabo
3 months
In every dinosaur we’ve looked at, the collagen fibers show a link between the cheek and jaw. This confirms that the soft tissues were like cheek muscles or ligaments.
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@MDSvantePaabo
Svante Paabo
3 months
This analogy perfectly captures the essence of scientific discovery! Even if we don't fully understand the underlying mechanisms yet, it's fascinating that DNA methylation can be a predictive marker. It's like having a clue in a grand puzzle that we're still working to complete.
@davidasinclair
David Sinclair
3 months
Discovering DNA methylation can predict your mortality without knowing why is like discovering you can tell time with a sundial without knowing the Earth revolves around the Sun.
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@MDSvantePaabo
Svante Paabo
3 months
I'm totally thrilled about the idea of bringing dinosaurs back to life.
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@MDSvantePaabo
Svante Paabo
3 months
The thyroid hormone receptor gene is key for managing metabolism and growth, making it super important for dinosaurs’ physiological functions. Zinc finger genes are also crucial as they help control gene expression, which in turn would have affected how dinosaurs developed and
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@MDSvantePaabo
Svante Paabo
3 months
RT @colossal: Our top track for resurrecting extinct species. Got a better banger? What should we queue up for the gene-splicing geniuses i….
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@MDSvantePaabo
Svante Paabo
3 months
here’s the scoop on what happens with these wild-type Tetrahymena (that’s a type of single-celled organism) and their 6mA (which is a type of DNA methylation). When a zygotic nucleus (basically the starting nucleus) that doesn’t have 6mA develops into a new macronucleus (the big.
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@MDSvantePaabo
Svante Paabo
3 months
Hey everyone! We just pulled off something amazing—we extracted DNA from the fossilized bones of a Caudipteryx (that’s a cool dinosaur with tail feathers)! Let’s share the super exciting details of this whole process on X!
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@MDSvantePaabo
Svante Paabo
3 months
here's the idea: We take these special genes called "reporter genes"—they code for proteins or enzymes that are super easy to detect. We hook them up with the DNA fragments we want to study, and then we put the whole thing into some cells. By checking out what the reporter gene
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@MDSvantePaabo
Svante Paabo
3 months
So, what's the hardest part about ancient genome sequencing? Is it controlling contamination? Has that problem pretty much been solved already?. Well, right now, we've got a pretty good handle on dealing with contamination. We've got lab precautions, we check for chemical changes
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