MChitraju
@MChitraju
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I am a scientist at Harvard University. My research focuses on understanding fat storage in normal physiology and in metabolic disease.
Joined August 2019
Happy to share our new paper. We showed that, mice lacking both the fat synthesis enzymes DGAT1 and DGAT2 are resistant to diet induced obesity and diabetes. Adipocytes are still functional!!!. Thanks to all the co-authors for contributions.
elifesciences.org
Inhibiting triglyceride storage in adipose tissue prevents obesity and improves metabolic health.
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RT @TobiWalther: Fat cells without fat? No problem !. …. according to the amazing @MChitraju in @eLife .
elifesciences.org
Inhibiting triglyceride storage in adipose tissue prevents obesity and improves metabolic health.
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What are the consequences of inhibiting fat storage in adipose tissue?. Please check out our new study. @MChitraju @AlexWFischer @YohannesAbere1 @KennyWang0208 @realTonyHui @TobiWalther @BobFarese @FandWLab @MET_HSPH .
biorxiv.org
SUMMARY Adipose tissue has at least two major functions: storing metabolic energy as triacylglycerols (TG) and coordinating metabolism by secreting hormones, such as leptin. In lipodystrophies,...
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RT @Cell_Metabolism: Targeting DGAT1 Ameliorates Glioblastoma by Increasing Fat Catabolism and Oxidative Stress
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Our new study showing,.Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis.
biorxiv.org
Brown adipocytes store metabolic energy as triglycerides (TG) in multilocular lipid droplets (LDs). Fatty acids released from brown adipocyte LDs by lipolysis are thought to activate and fuel...
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