Long-Sheng Song
@LongShengSong1
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A hawkeye, enjoy every small discovery, study heart failure, arrhythmia, Junctophilin-2……
Iowa City, IA
Joined July 2018
On Friday, Michael Welsh, MD, was presented with the 2025 Lasker-DeBakey Clinical Medical Research Award for discoveries in the treatment of cystic fibrosis. Also pictured: Drs. David Stoltz, Paul McCray, Joseph Zabner, Francis Collins, Michael Brown, and Alan Smith.
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Congratulations to Michael Welsh, MD, for being awarded the prestigious 2025 @LaskerFDN Clinical Medical Research Award for 40 years of life-changing research on #CysticFibrosis. https://t.co/CmpokXbcbU
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Our latest paper is in print today @CircAHA (second one in under a year). Huge thanks to Jinxi @jinxi_wang22 for leading this exciting and unexpected discovery of Junctophilin-2 in fibroblasts. @CircAHA @AHAScience @IntMedIowa @IowaMed
Junctophilin-2 is required in cardiac fibroblasts to orchestrate Ca homeostasis, promote fibrotic repair and angiogenesis post-myocardial infarction. @jinxi_wang22 @LongShengSong1
https://t.co/mrN3otHkSQ
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We have a fabulous line-up for the FASEB Ion Channel Regulation SRC! Still many opportunities to participate with several short talk and poster presentations available. Trainees this is a great meeting for you. Travel grants available. Submit an abstract today! @JonSilva_StL
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Congratulations Michael Welsh, MD, recipient of the 2025 Canada Gairdner International Award! Welsh is recognized for research in #CysticFibrosis, “thereby improving and saving countless lives.” https://t.co/qao5HCJWee
@GairdnerAwards IntMedatIowa
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@CircAHA @AHAScience @jinxi_wang22 @josephahill @IntMedatIowa @IowaMed Thank you, Shanna! Good luck with yours 🤞
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Thrilled to share our latest work on junctophilin-2 in @CircAHA @AHAScience led by @jinxi_wang22. Junctophilin-2 matters for heart Health! So grateful for @CircAHA editors promoting this study.@josephahill @IntMedatIowa @IowaMed
Preventing the cleavage of Junctophilin-2, an essential component of the E-C coupling apparatus, offers cardioprotective benefits and can be a promising approach for treating heart failure @LongShengSong1 @jinxi_wang22 @Iowamed @IntMedaIowa @UIowaResearch
https://t.co/6P8cfVf5J4
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An insulin signaling molecule also helps maintain heart rhythm, according to research led by Qian Shi, PhD. “We are opening exciting possibilities for developing therapies that could prevent life-threatening arrhythmias,” she says. https://t.co/PpJVlL8yGY
@IntMedatIowa
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Editor-in-Chief @josephahill speaks at #GWICC in Beijing, highlighting the global nature of @CircAHA and the #AHAJournals
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What a marvelous day celebrating the 50th Anniversary of the University of Iowa Francois Abboud Cardiovascular Research Center and the legacy of Dr. Abboud! A huge thank you to all our guest speakers who made this event truly memorable.@UIowaACRC @IntMedatIowa @IowaMed
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We cannot wait to see you all later this week! An event 50 years in the making with guests worthy of its decades of achievements. https://t.co/XorHrHDk5Z
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Cannot be happier for this being published in @CircAHA. Proud for the extraordinary, high quality work by @jinxi_wang22 and other team members. JP2 Matters🤞
Preventing the cleavage of Junctophilin-2, an essential component of the E-C coupling apparatus, offers cardioprotective benefits and can be a promising approach for treating heart failure @LongShengSong1 @jinxi_wang22 @Iowamed @IntMedaIowa @UIowaResearch
https://t.co/6P8cfVf5J4
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This month marks the 50th anniversary of the François M. Abboud Cardiovascular Research Center (ACRC) at @IowaMed, a milestone that celebrates half a century of groundbreaking research, clinical innovation, and educational excellence. https://t.co/HDNvULNNgL
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#OriginalResearch: IRE1α promotes the translation of TOP-motif transcripts to mediate hypertrophic cardiomyocyte growth. @josephahill @ShiqianLi1 @zhaowang4695 #AHAJournals
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This work spearheaded by @qianshi_uiowa reveals an important physiological role of IRS2 signaling in safeguarding cardiomycyte Ca2+ homeostasis. Proud to team with our leader @IntMedAbel on this exciting work from @IntMedatIowa @UIowaResearch @UIowaACRC
Just out in @CircAHA led by @qianshi_uiowa @LongShengSong1. Our new study showing novel mechanism by which insulin receptor substrate (IRS)2 signaling suppresses catecholamine induced ventricular arrythmia. @intmedatiowa, @AHAScience @theEndoSociety
https://t.co/f3uqZegWeh
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Just out in @ESC_journals our paper led by Qian Shi, @LongShengSong1 & Ethan Anderson, @Iowamed @IntMedatIowa elucidating the mechanisms for an anti-arrhythmic effect of MAO-Inhibition. Treating depression and heart disease with one drug?
academic.oup.com
AbstractAims. A mechanistic link between depression and risk of arrhythmias could be attributed to altered catecholamine metabolism in the heart. Monoamine
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#OriginalResearch: IRE1α promotes the translation of TOP-motif transcripts to mediate hypertrophic cardiomyocyte growth. @josephahill @ShiqianLi1 @zhaowang4695 #AHAJournals
ahajournals.org
BACKGROUND: Cardiomyocyte growth is coupled with active protein synthesis, which is one of the basic biological processes in living cells. However, it is unclear whether the unfolded protein response...
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