LenOvosh
@LenOvosch
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PhD student in @MembraneEnzymo1 at @Univgroningen. Average single-molecule enjoyer 🔬
Groningen, Nederland
Joined June 2020
🚨#LLPS: New trick for an old membrane protein! Homo- and hetero-condensates of a native membrane protein in E. coli tagged with PopTag 🔬🦠 LacY-PopTag is functional and localizes at cell poles or mobile foci in a curvature-dependent manner 🔗 https://t.co/1SmP3ZSUUX
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New PhD/PostDoc positions in exciting and challenging SynCell projects in Groningen! Multiple research groups involved https://t.co/aeQovusMqm
nature.com
12 PhD/Post doc positions for the design and engineering of synthetic cells
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Check out our new paper🎉 https://t.co/H1DAosQkvc Mechanosensitive Flipper-TR from @matile_group can be used for #SMLM in model membranes: ✨Single-molecule tracking of Flipper-TR in lipid bilayers with varying fluidity ✨Super-resolution imaging of both Lo and Ld GUVs
pubs.acs.org
A milestone in optical imaging of mechanical forces in cells has been the development of the family of flipper fluorescent probes able to report membrane tension noninvasively in living cells through...
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I'm thrilled to share our preprint on the phenotypic drug susceptibility test for Mycobacterium bovis BCG. One-day phenotypic drug susceptibility testing for Mycobacterium tuberculosis variant bovis BCG using single-cell imaging and a deep neural network
biorxiv.org
Drug-resistant tuberculosis (TB) kills approximately 200,000 people every year. A contributing factor is the slow turnaround time associated with anti-tuberculosis drug susceptibility diagnostics....
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We explored the mechanisms behind slower diffusion of cytosolic proteins at the cell poles of E. coli using SMdM microscopy Polyribosomes❌ mRNA❓ Protein aggregates, cell aging✅ Happy to be the part of Linnik @LenOvosch et al. team! @MembraneEnzymo1
https://t.co/DykJDkavuy
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What are the limiting factors of protein diffusion in bacteria periplasm and what influences it? We used single-protein displacement measurements and extensive computer simulations to give some answers on these question. https://t.co/E3dCZSqs1R Done in @MembraneEnzymo1 group
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Our new @PLOSCompBiol paper revealing effect of bacterial cell aging on protein mobility using combination of single-protein diffusion mapping 🔬 and computer simulations 🖥️ https://t.co/Daft7NirAi Done in @MembraneEnzymo1 group of @univgroningen
journals.plos.org
Author summary Knowledge of the location and mobility of molecules in living cells is paramount to understand cellular processes, protein interactions, folding and function. However, accurately...
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#EBSA2023 provided an opportunity to visit the Blue and Gold Nobel Hall, so that next time we know where to go to celebrate the receipt of the Nobel Prize ha-ha @pricelesska @LenOvosch
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