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Leann Tilley Profile
Leann Tilley

@LeannTilley

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Biochemist. Biophysicist. Malaria scientist. Leann thinks solving malaria will require collaborative interactions across academia and industry.

Joined September 2015
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@LeannTilley
Leann Tilley
22 days
Great work from Nat Ketprasit @nkprst, Chia-Wei Tai, Winnie Ye, Con Dogovski, Mike Griffin, Stanley Xie, University of Melbourne (@Bio21) & Monash Institute of Pharmaceutical Sciences, and colleagues from The Australian Synchrotron, Griffith University, IIT Bombay & ICGEB, India.
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@LeannTilley
Leann Tilley
22 days
The paper describes the structural and biochemical characterization of malaria parasite aspartate tRNA synthetase, revealing why it is more susceptible to hijacking than the equivalent human enzyme.
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@LeannTilley
Leann Tilley
22 days
Parasite aminoacyl tRNA synthetases catalyse the conjugation of DACM to an amino acid thereby disrupting the protein translation machinery. This makes the parasite the agent of its own demise.
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@LeannTilley
Leann Tilley
22 days
We are very pleased to share our publication in PLoS Pathogens (@PLOSPathogens) ( Our team explored a Streptomyces natural product, called dealanylascamycin (DACM). We showed it is a highly mechanism of action.
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@LeannTilley
Leann Tilley
25 days
Amazing Public Lecture by Nobel Laureate Donna Strickland, Nobel Prize in Physics in 2018, at RMIT’s Capitol Theatre. Strickland pioneered chirped pulse amplification for lasers, enabling innovations such as laser eye surgery. An inspirational talk about her love of photons.
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@LeannTilley
Leann Tilley
1 month
And thanks to my fellow panellists: Karena Waller, Shookofeh Shamsi, Tania de Koning-Ward, Simona John von Freyend and Lisa Jones. And to the highly engaged audience. Feel the passion & enjoy the journey.
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@LeannTilley
Leann Tilley
1 month
Very pleased to participate in an amazing Women in Parasitology session today as part of the Australian Society for Parasitology (@AS_Para) 2025 Conference. Thanks very much to Facilitators: Ghizal Siddiqui (@G__Siddiqui) and Hayley Bullen.
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@LeannTilley
Leann Tilley
1 month
Prof Pomat encouraged us continue the fabulous two-way interactions between Australia and PNG promoting medical research initiatives. Now needed more than ever.
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@LeannTilley
Leann Tilley
1 month
I enjoyed meeting Prof William Pomat, Director of the PNG Institute of Medical Research at the 50th Anniversary of the @WEHI_research Parasitology and Infectious Diseases Division. It was great to meet up with friends and colleagues, such as Prof Emeritus Robin Anders.
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@LeannTilley
Leann Tilley
2 months
RT @Rhys__G: Why make a cofactor when you can get it for free? . Our work, led by @FabianMunder, shows that bacteria from 22 phyla use th….
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Diverse bacteria use the high-affinity membrane transport protein PqqU to scavenge the nutrient PQQ from the environment.
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@LeannTilley
Leann Tilley
2 months
Botswana Chobe National Park. Amazing to see lion cubs playing.
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@LeannTilley
Leann Tilley
3 months
The Malaria Drug Accelerator meeting held in Livingstone, Zambia, was an amazing opportunity to connect with colleagues from across the work, working together to develop new antimalarial drugs.
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@LeannTilley
Leann Tilley
3 months
I really enjoyed visiting my colleagues, Sharon Prince (Deputy Dean, Research) and Edward Sturrock at the University of Cape Town (UCT). It was so rewarding to spend time with Sharon’s excellent and enthusiastic research team.
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@LeannTilley
Leann Tilley
4 months
RT @AS_Para: World Parasite Awareness Day is March 20th. Join us that day as we help to shed light on the importance of parasite prevention….
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@LeannTilley
Leann Tilley
5 months
Congratulations to Nutpakal Ketprasit (@nkprst). He submitted his thesis today on reaction hijacking of tRNA charging enzymes of Plasmodium & bacteria. This work will guide development of new treatments. Co-supervised by Stanley Xie and Stuart Ralph (@sturalph). @UniMelb
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@LeannTilley
Leann Tilley
5 months
RT @NobelPrize: Happy International Women’s Day!. We’re celebrating women who have changed the world. Here are all of the amazing women who….
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@LeannTilley
Leann Tilley
5 months
Thanks to the amazing and inspirational International Women's Day #IWD2025 Morning Tea Panel organised by the School of Biomedical Sciences @UniMelb. “It takes a village to raise a successful woman scientific leader”. Great buzz of collaboration and support at the event.
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@LeannTilley
Leann Tilley
5 months
RT @ChemistryUoM: ** Organic & Biological Seminar **. Prof. Dame Juliet A. Gerrard (Willsmore Fellow).University of Auckland @ScienceUoA @U….
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@LeannTilley
Leann Tilley
5 months
Congratulations Enrico.
@FrancesBiophys
Professor Frances Separovic
5 months
Congratulations to Enrico Gratton on becoming a @BiophysicalSoc Fellow at #bps2025 in LA.
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@LeannTilley
Leann Tilley
5 months
Amazing work. Congratulations.
@tham_lab
Wai-Hong Tham
6 months
Interested in #malaria transmission? Check out our new work using cryo-EM of ENDOGENOUS sexual stage parasites to determine the Pfs230-Pfs48/45 fertilisation complex - please read & share! . structures| nanobodies | human immune responses | mRNA-LNP .
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