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John D. Lambris, Ph.D. Profile
John D. Lambris, Ph.D.

@LambrisJD

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545
Following
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276

Dr. Ralph & Sallie Weaver Professor of Res. Medicine/ #University of Pennsylvania, Founder of #Amyndas, Inventor of #compstatins. Founder of #Aegean Conferences

Philadelphia, PA
Joined December 2017
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@AegeanConf
Aegean Conferences
5 months
Congratulations to all 17 trainee award recipients of the 20th Int’l Conference on #InnateImmunity #Sissi #Greece #Crete Fantastic Work!
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@LambrisJD
John D. Lambris, Ph.D.
6 months
Syfovre, the PEGylated version of a 2nd-generation compstatin-based C3 therapeutic (Cp05) discovered in my lab at the University of Pennsylvania ( https://t.co/ljsXlC2zXW) shows a consistent safety profile over 36 months of treatment, with increasing efficacy in reducing GA lesion
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pubmed.ncbi.nlm.nih.gov
Tryptophans at positions 4 and 7 of compstatin, a peptide complement inhibitor, are crucial for its interaction with C3. However, the nature of their involvement has not been studied to date. Here we...
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@LambrisJD
John D. Lambris, Ph.D.
6 months
Pleased to share our newly published paper entitled: "Clinical C3 Inhibition With AMY-101 Reveals Novel Insights Into IL-8–Driven Inflammation in COVID-19" https://t.co/XOhi93cEWX This work, which was done a few years back, investigated the effects of AMY-101 in treating severe
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onlinelibrary.wiley.com
Click on the article title to read more.
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@AegeanConf
Aegean Conferences
6 months
Program Updated: 17th Int'l Conference on #Complement #Therapeutics held at the #KalimeraKriti Conference Center from May 10-15 in #Sissi #Crete #Greece https://t.co/ZUA2mHGI5C @dmastellos @roumenina @LambrisJD
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@LambrisJD
John D. Lambris, Ph.D.
7 months
You can read our article here:
@LambrisJD
John D. Lambris, Ph.D.
7 months
Our News & Views article with @dmastellos discussing two recent Nature studies that report #granzymeK-mediated #complement activation in pathological contexts of CD8+ #Tcell-driven tissue #inflammation is now out in Nature Immunology
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@LambrisJD
John D. Lambris, Ph.D.
7 months
Our News & Views article with @dmastellos discussing two recent Nature studies that report #granzymeK-mediated #complement activation in pathological contexts of CD8+ #Tcell-driven tissue #inflammation is now out in Nature Immunology
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nature.com
Nature Immunology - Distinct proteolytic pathways share convergent activation patterns in many pathological contexts. Two new studies in Nature report on how effector memory-like CD8+ T cells...
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@LambrisJD
John D. Lambris, Ph.D.
7 months
The John & Rodanthi Lambris #academic sponsorships program ( https://t.co/mMiZcxcDR3) announces a call for five (5) one-year scholarships of €2,500 each (renewable upon evaluation) for the academic year 2025-2026 to university undergraduate and graduate students living in
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@AegeanConf
Aegean Conferences
9 months
Deadline Extended to Feb. 15. Abstract Submission and Trainee Award Application - 20th International Conference on #InnateImmunity in #Sissi #Crete #Greece https://t.co/X0WK9EABoH
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@LambrisJD
John D. Lambris, Ph.D.
9 months
This year's Aegean Conference on Complement Therapeutics features a speaker roster that promises to engage the audience, fostering a productive scientific debate and cross-pollination of ideas across diverse disciplines. A great mix of leading experts and emerging talent in
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@AegeanConf
Aegean Conferences
9 months
Speakers Posted: 17th Int'l Conference on #ComplementTherapeutics held in #Sissi, #Crete, #Greece from May 10-15, 2025 @KalimeraKriti organized by @LambrisJD @dmastellos @roumenina https://t.co/72C0EufeFY
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@LambrisJD
John D. Lambris, Ph.D.
11 months
Deeply honoured to be included in the 2024 Highly Cited Researchers list by Clarivate/Web of Science. This recognition reflects the courageous science, hard work and unwavering dedication of so many who have shared with me this truly exciting journey of scientific discovery over
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@dmastellos
Dimitris Mastellos
1 year
Amid the dust settling from the 'explosion' of clinical approvals, here's our spotlight w/@LambrisJD on the first ever therapy for patients with geographic atrophy, the #compstatin based #C3 targeted drug #Syfovre #pegcetacoplan Now out in @TrendsinPharma https://t.co/JzAdCa1fv5
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@AegeanConf
Aegean Conferences
1 year
Program Available: 7th International Conference on #ModelHosts in #Crete #Greece from Oct. 12-17. Registration still open! https://t.co/wldO7Nakqz
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@LambrisJD
John D. Lambris, Ph.D.
1 year
Add a placeholder on your calendars and make sure you join us in Greece for the 20th @AegeanConf on Innate Immunity! This milestone meeting will take place in Sissi, Crete from June 15-20, 2025. We will be discussing all the latest developments in various aspects of innate
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@LambrisJD
John D. Lambris, Ph.D.
1 year
Mark your calendars! The 17th International Conference on Complement Therapeutics will convene in Sissi, Crete, Greece from 10-15 May 2025. Join a vibrant meeting that brings together leading experts and innovators from both academia and industry to share new results, challenge
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@LambrisJD
John D. Lambris, Ph.D.
1 year
Σας ευχαριστώ για το εξαιρετικό άρθρο που αποτυπώνει ακριβώς το πώς αντιλαμβάνομαι την σχέση μου με την έρευνα, την προσφορά στον άνθρωπο, την δύναμη των ανθρώπινων σχέσεων και την ουσία της ζωής. https://t.co/ClpqWmPsd6 via @ΑΠΟΨΗ - press
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apopsi-press.gr
Οι φιλοξενούμενοι καθηγητές της ιατρικής, που μίλησαν στην εκδήλωση, δεν μάσησαν τα λόγια τους. Περιέγραψαν με σαφήνεια τον χαρακτήρα του ορμώμενου εκ Ροδαυγής Άρτας Γιάννη Λάμπρη και τον τρόπο με...
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@AegeanConf
Aegean Conferences
1 year
Congratulations to the trainee travel award recipients during the #mesenchymal conference
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@LambrisJD
John D. Lambris, Ph.D.
1 year
My colleagues, collaborators, postdocs and students - THANK YOU for making this year's Aegean meeting on Complement Therapeutics an unforgettable experience for me! I was humbled to hear how I was able to positively influence so many of you - researchers and scientists from
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@LambrisJD
John D. Lambris, Ph.D.
1 year
This year's Aegean conference on Complement Therapeutics had a heartmoving surprise lurking for me! My co-organizers Lubka and Dimitris decided to dedicate the meeting to my 70th birthday, carrying out a plan that was kept in full secrecy until the kick-off of the meeting. Dear
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