VachaLab
@LabVacha
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Biological membranes, proteins. and their interactions at @CEITEC_Brno
Brno, Czech Republic
Joined June 2019
These two works now have their great covers as well 🙂
Third, @RivelTimothee and @DenysBiriukov presented new collective variables to study the energetics of lipid membrane pores. https://t.co/1a1ZUu5qil Good job!
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Robert Vácha from @CEITEC_Brno @MasarykUni has been awarded ERC Proof of Concept grant for preclinical testing of new antimicrobial peptides that have the potential to significantly contribute to the fight the antibiotic resistance in bacteria. Congratulations! 👏 #CEITECScience
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Prof. Robert Vácha @LabVacha je mezi úspěšnými žadateli, kteří získali grant Proof of Concept @ERC_Research 👏 Podpořený projekt se bude věnovat boji s rezistentními bakteriemi s pomocí antimikrobiálních peptidů. 👇👇👇
An archaeologist will aid the fight against food fraud. A computational biologist will help find new drugs to combat cancer & a biomedical engineer will better visualise blood microcirculation. More on the exciting new #ERCPoC projects 👉 https://t.co/4nHjjdLomg
@EUScienceInnov
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Third, @RivelTimothee and @DenysBiriukov presented new collective variables to study the energetics of lipid membrane pores. https://t.co/1a1ZUu5qil Good job!
pubs.acs.org
Understanding the molecular mechanisms of pore formation is crucial for elucidating fundamental biological processes and developing therapeutic strategies, such as the design of drug delivery systems...
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Second, Mehrnoosh showed how to "split" lipids to accelerate the sampling of all-atom lipid membranes. https://t.co/hC8nmTAF3J
pubs.acs.org
All-atom molecular dynamics simulations are powerful tools for studying cell membranes and their interactions with proteins and other molecules. However, these processes occur on time scales determ...
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We’re off to a strong start in 2025. First, work of Láďa on enhanced diffusion received a beautiful cover. https://t.co/SEPieJ5M49
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Grateful for the opportunity to share insights on our work, achievements, and future goals with the @CEITEC_Brno communications team:
ceitec.eu
Biophysicist Robert Vácha specializes in a rather unconventional field within the life sciences at CEITEC Masaryk University (MUNI) – he uses computer simulations to study interactions between...
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Quick updates: check out another stellar work by Láďa Bartoš: https://t.co/SEPieJ5eeB 👏 Oh, and we're now on 🦋 too!
pubs.rsc.org
The diffusion of macromolecules, nanoparticles, viruses, and bacteria is essential for targeting hosts or cellular destinations. While these entities can bind to receptors and ligands on host...
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We've received a new GAČR Weave project in collaboration with German and Austrian groups, where we will focus on how lipid asymmetry affects protein function! Thereby, we also have an open Ph.D. position! @CEITEC_Brno
https://t.co/MIh3FYlsvJ
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Congratulations to Francesco and our collaborators on our latest publication on phase separation and phosphorylation, now live in @NatureComms! @CEITEC_Brno @NIVBcz @ERC_Research
https://t.co/yEdbnPlr7B
nature.com
Nature Communications - The authors explore sequence-encoded molecular grammar underlying the liquid liquid phase-separation of the human RNA polymerase II C-terminal domain and demonstrate that...
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Our research on tackling drug-resistant bacteria has been featured in Czech media again! Check out the coverage here (only in Czech):
radiozurnal.rozhlas.cz
00:00 témata magazínu00:20 Nobelovy ceny za vědu02:50 peptidy proti rezistentním bakteriím07:00 focení bakteriofágů10:45 AI a vyhodnocování vzorků prostaty14:30 rozhovor s Romanem Zachovalem18:30...
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📢 Attention students of @muni_cz @MasarykUni @CEITEC_Brno! Our Survival Guide course on molecular dynamics simulations is back! Based on your feedback from last year, my postdocs have enhanced the course to make it even more accessible and effective. Spread the word and sign up!
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Excellent work by @MehrHaz on antimicrobial peptide Buforin 2 and its behavior within and across cellular membranes! Supported by @ERC_Research & @NIVBcz and done at @CEITEC_Brno
https://t.co/SoGS18xHnb
pubs.acs.org
Despite ongoing research on antimicrobial peptides (AMPs) and cell-penetrating peptides (CPPs), their precise translocation mechanism remains elusive. This includes Buforin 2 (BF2), a well-known AMP,...
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We are thrilled to have our work featured on the cover of #JMedChem !! @ACS4Authors @ACSBioMed @LabVacha @CEITEC_Brno @delafuenteupenn #MyACSCover
Paper published in #JMedChem, our computer-designed peptides fight bacterial infections and cancer. De novo antimicrobial and pH-sensitive anticancer peptides from the barrel-stave pore class @LabVacha @CEITEC_Brno @MasarykUni @delafuenteupenn @ACSBioMed
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We’re thrilled to have our work featured in the Czech media! https://t.co/VmIvc6SCZA
https://t.co/3IeI8HaSaP
ct24.ceskatelevize.cz
Významný krok vpřed v potírání bakteriálních infekcí, které jsou odolné vůči antibiotikům, udělali vědci z institutu CEITEC Masarykovy univerzity. Navrhli s pomocí počítačové simulace speciální...
🚨 Just out: Our computationally-designed peptides are taking down bacterial and cancer cells! Incredible work by Rahul Deb! 👏 https://t.co/Rl5ovF7BSc
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🚨 Just out: Our computationally-designed peptides are taking down bacterial and cancer cells! Incredible work by Rahul Deb! 👏 https://t.co/Rl5ovF7BSc
pubs.acs.org
Peptides that form transmembrane barrel-stave pores are potential alternative therapeutics for bacterial infections and cancer. However, their optimization for clinical translation is hampered by a...
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Scientists at @CEITEC_Brno @MasarykUni design nanoparticles for drug delivery through spontaneous membrane fusion 💊 🔬 @LabVacha Read more here 👉 https://t.co/YKMNiQ36bl
#CEITECScience
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Prof. @mleptin, President of @ERC_Research, is coming to Brno on 13 June to open a conference at @CEITEC_Brno @MasarykUni and join a panel discussion on how we can close the gap in the success rate of Czech ERC grant candidates. https://t.co/4783JN2ioM
@brnoregion
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