Li-Kun Phng
@LabPhng
Followers
367
Following
234
Media
42
Statuses
148
PI at RIKEN BDR. Vascular biologist. ❤️ endothelial cells @phnglab.bsky.social
Kobe, Japan
Joined March 2021
RT @BDR_RIKEN: 👩🔬The BDR Diversity Working Group organized an event in April titled, "Inspiring Women in Science," featuring talks by thre….
bdr.riken.jp
0
3
0
RT @the_Node: Meet the lab of @LabPhng, based @BDR_RIKEN, Kobe, Japan. The lab is interested in vascular #morphogenesis, in particular, end….
thenode.biologists.com
Meet the Phng Lab, based at the RIKEN Center for Biosystems Dynamics Research, Japan. The lab is interested in vascular morphogenesis and, in particular, endothelial cell mechanobiology.
0
5
0
RT @the_Node: Exploring the Uncharted Waters of Endothelial Tip Cell Migration: A Story of Aquaporins, Hydrostatic Pressure, and Angiogenes….
thenode.biologists.com
Behind the Paper Story by Li-Kun Phng
0
2
0
RT @riken_en: Water flow helps the development of new blood vessels. #developmentalbiology #angiogenesis #zebrafish #riken @LabPhng @BDR_RI….
riken.jp
RIKEN researchers have shown that that hydrostatic pressure is one of two mechanisms that control endothelial cell migration during angiogenic sprouting in zebrafish
0
13
0
Kudos to @yamacy23 for her immense effort in putting the whole story together. Check out this laser ablation experiment that she did! And thank you to all coauthors for their input @MechgenLab @Lagendijk_lab @vizcie.
0
0
2
In the absence of krit1/ccm1, ECs lack circumferential actin, undergo reduced cell deformation and exhibit enlarged vessels, thus providing a mechanistic understanding of how cerebral cavernous malformation arises.
1
0
1
We discovered that the combined activities of EC deformation and changes in cell number define vessel diameter and length. We further showed that circumferential actomyosin bundles bearing high tensile forces deform ECs to constrict vessels.
1
0
0
Delighted to share latest preprint from @LabPhng @BDR_RIKEN where we investigated how #endothelial cell behaviours and #mechanobiology control blood vessel size in #zebrafish.
4
12
45
Perfect weather to celebrate 8th year anniversary of @LabPhng @BDR_RIKEN at Suma Beach! Thank you to all past and present lab members for their hard work! @yamacy23 @swesoe2
1
1
31
RT @SameerThukral6: Prof Fumio Motegi gave a career talk about learnings from failure at the recent BDR-Launchpad event for ECRs. Learning….
0
2
0
RT @endothelialnews: Drs. Stephan Huveneers (@Huveneers_Lab) and Li-Kun Phng (@LabPhng) discuss new conceptual advances gained from in vitr….
0
6
0
RT @Huveneers_Lab: Endothelial cell mechanics and dynamics in angiogenesis Dynamic interaction with @LabPhng to o….
0
27
0
Had the pleasure of hosting @SiekmannLab who visited @LabPhng @BDR_RIKEN en route to #IZFC2024 in Kyoto recently. Take home message from his talk - the importance of veins in making blood vessels! #zebrafish
0
1
18
Second paper published within a week from @LabPhng @BDR_RIKEN where we demonstrate an important role of water flow and hydrostatic pressure in endothelial cell #mechanics #migration in #zebrafish. @eLife.
elifesciences.org
Investigation of Aquaporin water channels unveils water inflow and build-up of hydrostatic pressure in endothelial tip cells as a novel mechanism of endothelial cell migration and blood vessel...
2
9
45
Pleased to share a review written by @LabPhng and @BenjaminHogan13 about #endothelial cell transitions in #zebrafish vascular #devbio!
onlinelibrary.wiley.com
The vertebrate vasculature is an elaborate, interconnected, hierarchical network of blood and lymphatic blood vessels found in all tissues and organs. The formation of functional vascular networks...
0
11
36