Kent Søe
@KentSoee
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Strong interest for #bone #research and #osteoclast in the context of #osteoporosis, #breastcancer, and #prostatecancer. @Patologi_SDU @OUHhospital @SUND_SDU
South Denmark, Denmark
Joined March 2019
New paper out in @JBMRPlus! Using a time-lapse co-culture approach with osteoclasts and reversal cells, we show that reversal cells prefer pits over trenches, but that intermediate #CatK inhibition boosts their attraction and maturation into #osteoblasts
academic.oup.com
Abstract. Cathepsin K inhibitors are well known for their inhibitory activity against bone resorption but were also reported to preserve bone formation in
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The suggestions for the ECTS 2026 Programme are open! Suggestions are welcomed for incorporation into the following sessions: Plenary Symposia, Clinical Concurrent Symposia, Basic Science Concurrent Symposia. https://t.co/ryOlLBh6GK
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Do we make the best of the synergistic potential when basic and clinical scientists work together? This is the topic we discuss - as members of the Basic and Clincal Science Action Groups of @ECTS_soc and @AcademyEcts! https://t.co/sRDWbYZ5ZQ
@ASBMR @IFMRSGlobal @iofbonehealth
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If you are interested in the impact of long non-coding RNA and uRNA on #human #osteoclast differentiation and #bone resorption, you may be interested in our paper published late last year - Open Access https://t.co/rQ80C9sKsI
https://t.co/yaW7zVzeBc
nature.com
Cell Death & Disease - Stage-specific modulation of multinucleation, fusion, and resorption by the long non-coding RNA DLEU1 and miR-16 in human primary osteoclasts
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I have created a BlueSky profile - if you wish, please start to follow me there for updates on my research. I would also be happy to follow you back on BlueSky 😊 - see you there soon 😉 https://t.co/yaW7zVzeBc
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#ECTS2025Website is Live! The congress website is now live and you can find the latest information on the scientific programme, abstract submission and registrations. Come back regularly as we will continue updating it as we make progress in the planning. https://t.co/Pi5JqRXjka
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Using time-lapse recording, we show in @SciReports how human #osteoclasts respond to inhibition of #CatK. We show that fusion during bone resorption may overcome inhibition! Lots of video material included.
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Today I joined the BigBang Conference for teachers of science in secondary and highschool. I presented on #osteoporosis followed by a discussion on how this can be made relevant for pupils in 7th to 10th grade. Very stimulating and very engaged teachers - a great pleasure 😊
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Legalized use of #cannabis is debated and in many countries it is legalized. We have tested the effect of the cannabinoids, #THC and #CBD, on human bone cells, #osteoclasts and #osteoblasts. #THC and #CBD use may have consequences for bone health. https://t.co/QlrLvIB6uK
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This open-access publication is the result of combining great international collaborations with fantastic supervisors and some osteoclast genetic dust from The Bioinformaticians magic wand: https://t.co/m622SZqcPQ
@frost_nielsen @RauchLabSDU @caroline_gorvin @KentSoee @KMEBLab
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A new study aimed to investigate whether rhPTH(1–84) continued to activate intracortical bone remodeling & promoted the transition from erosion to formation & whether this effect was transitory when rhPTH(1–84) was discontinued @LevinGeiser
https://t.co/qFe9xO2ta1
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Excellent talk from Dr. Megan Weivoda @MegVoda on osteoclast-immune interactions and effects of osteoclast depletion on immune lineages! #ASBMR2023
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Gemstone has succeeded thanks to the teamwork of a large group of scientists from some 30 countries all around the world 🤩🤩🤩 This is not an end and it’s going to continue achieving more goals
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This is a fantastic opportunity! 🤓 join our great team and be part of developing new computer-assisted analyses on human #bone
Do you dream of working with molecular histology and histomorphometry in #bone?🤩Our lab is looking for a post-doc to investigate the effects of bisphosphanates on bone quality in relation to atypical femur fractures. https://t.co/PKdwtvMcvk
@ECTS_soc @The_JBMR @Bones #postdoc
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Happy to share our latest work in "Clinical Epigenetics". #EWAS reveals that smoking causes changes in DNA methylation at the #PBMC level rendering resulting #osteoclasts less sensitive to zoledronic acid. Open Access https://t.co/UKI4IwK3cR
https://t.co/rxjKnKN6cP
@CostGemstone
pubmed.ncbi.nlm.nih.gov
We identified 59 CpGs displaying genome-wide significance (p < 1e-08) with a false discovery rate (FDR) < 0.05 for the smoking-dependent association with IC50. Among them, 3 CpGs have p < 1e-08 and...
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