Jason Sperry
@Jjasonsperrymd
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Father, Trauma Surgeon, Emergency General Surgeon, Trauma Clinical Trialist and Outcomes Researcher
Pittsburgh, PA
Joined December 2013
Results of the PAMPer trial. #pamperstudy Prehospital Plasma during Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock | NEJM
nejm.org
After a person has been injured, prehospital administration of plasma in addition to the initiation of standard resuscitation procedures in the prehospital environment may reduce the risk of downst...
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LITES is at #AAST2025! Investigators and the LITES-curious are welcome to come to our reception tonight (Thursday) – 5-7pm in the Vermont room on the 5th floor. Come visit with @Jjasonsperrymd; PACT, PAIN, and CAVALIER staff; and admins. Hope to see you there!
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Achievement of hemostasis is associated with coagulation, transfusion volumes and mortality benefits. Early whole blood resuscitation is associated with a greater independent odds of achieving hemostasis & at an earlier time point over the first 4 hours. https://t.co/bKifu7qHGb
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Next up at #WTA2025 : Pediatric tourniquet use in children associated with improved stability and no adverse events! @PittSurgery @ChristineLeeper @PittPedsSurg
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The NFL Physicians Society has awarded the Arthur C. Rettig Award for Academic Excellence to David Okonkwo—team neurosurgeon for the Pittsburgh Steelers—for his groundbreaking concussion research. https://t.co/JzW8YhwQpd
@NFL @Pitt_NCTC @PittHealthSci @NFLPS1966 @steelers @UPMC
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❇️Best of Trauma❇️ Achieving hemostasis improves coagulation, reduces transfusions, and lowers mortality. Early whole blood resuscitation increases the likelihood and speed of hemostasis within the first 4 hours. @jjasonsperrymd
https://t.co/bKifu7qHGb
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3 publications in 3 wks; LITES is on a roll! Check out “Adverse Prehosp. Events & Outcomes after TBI" - data on almost 15,000 adults w/ TBI to assess effects of hypoxia, hypotension & hypocarbia on pt. outcomes. Thank you TO-1 contributors & @AmeliaMaiga !
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New LITES manuscript! Whole blood resus. associated w/ greater achievement of early hemostasis https://t.co/1ziRTbVrwM Thank you @Guyettef @bryanacotton1 @Jjasonsperrymd @NicholasNamias @DenverHealthMed @MartinSchreib10 @PennTrauma @UTSW_Surgery @PittTTMRC !
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Early cold stored platelet transfusion in TBI patients—compared to room temp platelet transfusion—shows lower rate of neurosurgical operative intervention without increase in adverse events. https://t.co/l9zxOCeqWH
@Pitt_NCTC @UPMCPhysicianEd @AnnalsofSurgery @PittHealthSci
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Novel phase 2 randomized clinical trial characterizing feasibilty, safety, efficacy of Cold Stored Platelets in TBI @LITESnetwork @PittSurgery @macky_neal @PittTweet @Guyettef
pubmed.ncbi.nlm.nih.gov
In brain-injured patients requiring platelet transfusion, early CSP transfusion is feasible and did not result in improved 6-month Glasgow Coma Scale-extended scores. Early CSP transfusion was...
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Check out our article in @AnnalsofSurgery! It's not brain surgery - or at least not for TBI pts who received cold stored platelets. 😉 CriSP-TBI found that early CSP transfusion reduced need for operative intervention w/o increase in AE. https://t.co/HVBk16Jajb
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2nd yr @traumadoctors ACS fellow Chris Reed @pitttrauma received funding today as PI for his basic science work on Factor IX in #trauma @PittTTMRC. Bold statement - NO BETTER fellowship to balance clinical and research excellence in ACS. Fight me @bryanacotton1 😁@Jjasonsperrymd
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An analysis was performed using data from two large, double-blinded, randomized prehospital TXA trials. Prehospital TXA is safe & independently associated with a dose-dependent lower 28-day mortality risk & lower 24-hour red cell transfusion requirement. https://t.co/2lYJHoNEZW
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With the beginning of the holiday season underway, LITES wants to express our gratitude for the prehospital, emergency medicine, trauma surgery, and critical care providers who work 24/7 to take care of injured patients! We hope everyone had a safe holiday weekend!
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First pediatric subject enrolled today at Le Bonheur Children's hospital in the first traumatic bleeding platform trial performed. Will LTOWB be superior to components? TXA to placebo? Will find out eventually! @theTHORnetwork @PittTTMRC
@PittSurgery
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The meeting for public discussion of evidence based recommendations for the treatment of hemorrhagic shock in women and therapies to reduce the risk of HDFN was a huge success! 20 recommendations that will save thousands of lives. @AlloHope @theTHORnetwork @AABB @traumadoctors
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Bethany Weathersby and @PhilSpinellaMD with baby Noah, whose mother was alloimmunized and developed HDFN, opened up the 2024 Symposium on Emergency Transfusion in Females with Childbearing Potential! @AlloHope #HDFN #alloimmunization #transfusion #MedX
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An analysis was performed using data from two large, double-blinded, randomized prehospital TXA trials. Prehospital TXA is safe & independently associated with a dose-dependent lower 28-day mortality risk & lower 24-hour red cell transfusion requirement. https://t.co/2lYJHoNEZW
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Many Congratulations to @joshua_b_brown on his new role as Statistical Editor for @JAMASurgery #SurgeryResearch #SurgicalExcellence #DataScience #AcademicSurgery @PittTweet @UPMC @PittCCM @PittGIM @ChildrensPgh @PittPubHealth @PittPubHealth @PittHealthSci @PittNeurosurg
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Exciting news! We've been featured in INSIDEPittResearch. Congratulations! @Guyettef, @Jjasonsperrymd, and Dr. Wisniewski #TraumaCare #Research #PittMed #DoD @UPMC @LITESnetwork
@PittPubHealth @UPMC
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It's just a platelet -- how complex could it be?!? Spoiler: very. @LucyKornblith beautifully demonstrates how storage affects platelet RNA structure. But HOW?!? She has a hypothesis...You'll hear about it soon #thor2024 #platelets #coag #transfusion #MedX
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