JMCC Plus
@JMCCPlus
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Open Access journal of the International Society for Heart Research.
Joined March 2023
We often treat #diabetes and #heart #disease separately — but they’re connected🫀. A recent study from Srinivas, Alluri et al. from @ODU shows that removing CHOP in β-cells protects against both metabolic dysfunction and cardiac fibrosis in T2D mice. https://t.co/iCOSGG4LST
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🫀 New in JMCC Plus! Age, sex & vessel region shape vasomotor function in the descending thoracic #aorta — with #endothelial integrity & relaxation declining with age. Want to know more- check out Saemann et al.: https://t.co/ffgaTDTtA2
#VascularBiology
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New work from @nicoleyorkova and the group of @dr_swayne charts how H9c2 heart cells change shape, signal, & express genes during differentiation—revealing both their promise & limits as #cardiomyocyte models. #CardioTwitter @JMCCardiology
@LeighWicki
https://t.co/7lknrbethj
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Early Career Investigators, don't miss your chance to present an abstract at the ISHR-NAS ECI Webinar. Deadline to submit an abstract is Oct. 31. Details at https://t.co/N8esMPEnLw
@ECI_ISHR @ISHR_ECI @ISHR_NAS @JMCCPlus
Attention Early Career Investigators! ISHR-NAS will host a webinar on Dec. 4, featuring select presentations from Post-Docs and PhD Students. Submit your abstract by Oct 31 to be considered for presentation. Learn more & register: https://t.co/N8esMPEnLw
@ECI_ISHR @ISHR_NAS
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Ever wondered how #Calcium channels cluster in #iPSC derived #Cardiomyocytes? New work just published from Schwenzer et al. should put your mind at rest as they investigated just that! Check out the latest paper for more information https://t.co/KZWLOTcKcC
@uniGoettingen
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Looking for some weekend reading? 📜 New work from from the @HeartInstitute show how metabolic substrates regulate effects of Wnt/β-catenin signaling in #cardiomyocytes, specifically affecting regulation of #Connexin43
@WenbinLiang2 @PeterPLiu_MD
https://t.co/HcXD2jQjTk
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Looking for some weekend reading? 📑📑 New work from @jsauce7 and colleagues @UVA used live-cell #imaging to track single-cell fate decisions of #cardiomyocytes- Grow or Die? https://t.co/YZw24pbAAH
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Ever wondered how the analgesic agent you use may affect cardiac contraction? 🫀🔬 New work from Duursma et al. from @amsterdamumc looked into it! https://t.co/YBp82XYKpT
@JolandavanderV4 @PavlovicDavor @IshrMci @ISHR_ES @ISHR_NAS @ISHR_LAT @ISHR_AUS
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New work out in the from @UniofOxford looks into developing sex-specific human ventricular #electromechanical multiscale models. Given the importance of #biologicalsex in #CardiovascularHealth this could be a very important tool! https://t.co/sDYJ6Mbl0R
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Noureddine et al show that a mouse model of the ACTN2 #HCM-associated M228T variant displays #atrial electrical alterations, independent of structural remodelling. An important insight into genotype-phenotype relationships in inherited cardiomyopathies! 🔗 https://t.co/Uxtj8nGfFi
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🧬 New pig models of neonatal #HCM show severe cardiac #hypertrophy and perinatal lethality from MYBPC3 and MYH7 mutations. Pigs were highly sensitive to sarcomeric gene disruption, developing severe HCM, suggesting they may not be ideal genetic models. 🔗 https://t.co/4DOrdtMTbp
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12-week-old #ob/ob mice show mild DCM with no major structural changes in #MAMs. Proteins linked to lipid metabolism and stress response were increased in MAMs, while hypoxic stress triggered more cardiomyocyte death. https://t.co/kej2AFvEVr
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New paper out in our September issue from @BassStringer and colleagues @BakerResearchAu looking at PI3K Exploring a new #genetherapy to improve heart function in mice and sheep. https://t.co/aiUjUjJxt9
@peggyc0517
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Calling all #immunofluorescence scientists! Teng et al. showed glyoxal enhances IF signal and co-localisation while reducing staining artifacts, making it a superior alternative to PFA in murine cardiac tissue research. https://t.co/C8sxsEbuhM
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JMCC and JMCC Plus are now on LinkedIn! Follow our joint JMCC Journals account at https://t.co/TkfX2zooyo
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Mitochondrial, stress-responsive #SIRT4 worsens #cardiomyopathy when overexpressed by increasing mitochondrial #ROS and profibrotic transcriptional activity. Cardiac function improved and fibrosis reversed with mitochondria-targeted antioxidant #MitoQ. 🔗 https://t.co/ZeB8GJQ73a
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📈 Circulating adropin is linked to higher risk of #AKI in patients with acutely decompensated #heartfailure (#ADHF) after decongestive therapy. It outperformed conventional biomarkers like urinary ACR and NT-proBNP. #CardioRenal #Biomarkers
https://t.co/i23SH6j9PQ
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Kazantzi et al show that #MEK–ERK1/2 and #PKC pathways independently and synergistically modulate ETB receptor upregulation under flow cessation. These signalling axes may be promising targets for #cerebrovascular disease. @UCPH_Research
https://t.co/TTCXOkGmsm
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You can now also follow updates from JMCC Plus and @JMCCardiology on Linkedin! https://t.co/vv06kabl05
linkedin.com
JMCC Journals | 108 followers on LinkedIn. Journal of Molecular and Cellular Cardiology (JMCC), and JMCC Plus. Official journals of ISHR. | The Journal of Molecular and Cellular Cardiology, and its...
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On your way to the #EWGCCE meeting or just looking for some weekend reading ready for Monday morning! New work just out from Fowler et al, invesigated the role of subthreshold #DADs on arrhythmia generation in #CPVT! https://t.co/8uCideHaue
@AnaMGmez4 @Physicsoftheart
Less than 24 hours to go before the #EWGCCE meeting kicks off @escardio #HeartHouse in the South of France! Looking forward to a great scientific programme and meeting up with colleagues and friends over the next days! Safe travels all! @EWGCCEChair @JordiHeijman @OdeningLab
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