Welcome to The Journal of Cardiovascular Electrophysiology 4.0

🕐 Timing matters in AF ablation. Early ablation (≤ 1 year after dx) lowered AF-recurrence risk by 22 % in HFrEF and 17 % in HFpEF, TriNetX multicenter analysis – now in @JCardioEP 🔗 https://t.co/2ezN7peAjY ✒��@MayoClinicCV @DrDeese99 @abhishek_mbbs @ElBenawiH @M_EISA_2012

EPIC‑BrS: Epicardial ablation sharply reduces VF in malignant Brugada. Adjunctive ablation may outperform ICD-only strategy 🔗 https://t.co/hBEc50Prz7 ✒️ @LucasMBarbosa01 @OliveiraVMR

✒️ @JoseDelgadoMD @laserlead @DrKhazenCesar

https://t.co/lre7eXHHoW

🤔 Is LBBAP CRT cost-effective compared with BVP CRT? ✒️ Find out the results in a recent @JCardioEP manuscript by : @jmsanchezmoreno @ManoloMolina8  @ArritmiasGr @hospital_hvn @Cardio_HURS @CorazonHuvr @AGSSurSevilla 🔗 https://t.co/wPEbvDbc5a

PWI is definitely not appropriate for all patients with persistent AF. It has been shown to be effective in some cases (low/fractionated voltage, high burden of spatiotemporal dispersion) but in select trials without replication. Persistent AF is an area ripe for continued

PVI+ is the one area where RCTs have been unable to supercede anecdotes – because operator bias is so powerful. Only two randomized trials have shown efficacy beyond PVI (CONVERGE and VENUS), yet only a minority have adopted. And multiple PWI studies show no systematic benefit

A 72 y.o. man with a CRT-D developed acute HF due to biventricular pacing tachycardia > 100/min. Frequent ventricular ectopics activated ventricular rate stabilisation for rate smoothing which paradoxically worsened heart failure. #Epeeps

🚀New on @JCardioEP 🎓"Adverse Effect of Ventricular Rate Regularization Pacing in Biventricular Cardiac Resynchronization Therapy" by Chu-Pak Lau et al https://t.co/5k4m7rt8Fx

With cannabis use on the rise, what are the cardiac risks? This large multicenter study reveals cannabis users face higher rates of atrial & ventricular arrhythmias compared to matched controls. #Epeeps

🚀New on @JCardioEP "Cannabis Use and the Risk of Arrhythmias: Insights From a Large Retrospective Multicenter Analysis" by @juanpvf1708 et al https://t.co/UCbrgIqq4J

VT Ablation in #LVAD Patients  (325 ablations, 300 patients): -  VT recurrence: 38% - Complication rate: 8% - Most common mechanism: Scar-related VT - Novel finding: HM3-specific EMI in ~50% of cases #EPeeps

🚀 New in @JCardioEP 📷 "Contemporary Outcomes of Ventricular Tachycardia Ablation in Left Ventricular Assist Device Therapy: A Meta-Analysis" by @TheVash12 et al @Davilandre https://t.co/PxSeuP0Ter

New insights in hybrid AF ablation: functional gaps & atrial fibrosis predict early arrhythmia recurrence. High-density mapping helps target completion lesions and improve rhythm success. #Epeeps

📜 Functional Gaps and Atrial Fibrosis as Predictors of Early Arrhythmia Recurrence After Robotic-Enhanced Hybrid Ablation for Persistent Atrial Fibrillation by @EduardoCelenta1 et al @nmsdegroot https://t.co/GGiUsggHxM

V6 R-wave peak time during right ventricular septal pacing predicts successful LBBAP implantation in heart failure patients with LBBB. This simple ECG marker correlates with scar burden and guides intra-operative CRT strategy. #LBBAP #CRT #EPeeps

🚀 New in @JCardioEP 🎓 "Right Ventricular Septal Pacing-Derived V6 R-Wave Peak Time Predicts Successful Left Bundle Branch Area Pacing in Patients With Heart Failure and Left Bundle Branch Block" by Mengxing Cai et al https://t.co/VWexnMJL42

Findings from this single-center analysis show that PFA is beneficial in AF patients regardless of their age by being associated with either significantly higher arrhythmia-free survival or longer time to recurrence compared to similar age-group patients undergoing thermal CA

🚀Check out in the @JCardioEP 🎓 "Long-Term Outcome of Radiofrequency Versus Pulsed-Field Ablation in Atrial Fibrillation Patients Aged More Than 60 Years Undergoing Their First Catheter Ablation" by @PamelaH33 et al @natale_md 📷

✅In Cyprus, sudden death affects 1 in 46,000 people aged 1–35 years annually, mostly due to cardiomyopathies. >25% occur during sports. This 11-year national epidemiological study provides key data on sudden deaths, highlighting the need for early screening and genetic testing.