Journal of Biological Chemistry
@jbiolchem
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The Journal of Biological Chemistry is a publication of @ASBMB. Publishing research motivated by biology, enabled by chemistry.
Rockville, Md.
Joined March 2012
New in JBC press: "Scientists' data suggest that CNOT4 exerts opposite effects on mRNA metabolism compared to CNOT1." Learn more: https://t.co/W1zj5RDyLK
#jbiolchem
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New in JBC press: "Researchers demonstrate that this EAS1-mediated suppression of ACE2 exacerbates cellular apoptosis induced by TNF-α and hypoxia." Learn more: https://t.co/7VMgAEijtc
#jbiolchem
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We're back with another RUMBLE ROUNDTABLE with Chavez, Joker, and Redd! All things RUMBLE! Pain points, celebrations, good, bad, all of it! We want to hear from YOU! LINKS IN COMMENTS BELOW! SATURDAY NOV 22ND 6PM EST! FOLLOW and SHARE OUT!
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🚀 #AuthorInterview | Dr. Uzma Salim @UzmaSalim4, PhD from Prof. Vivekanandan Perumal’s lab at @iitdelhi, discusses her work “The G Factor: RNA G-Quadruplexes Drive Mammalian Mirtron Biogenesis” published in @jbiolchem. Read more 👉 https://t.co/M6HJKqgWFx
#RNA #ResearchSpotlight
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@SanhitaRoy12 @jbiolchem @RIDDHIA79109299 @akshita1699 @Srijita__Kundu Congratulations Sanhita!!! This is such a cool picture!
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Spend #Halloween with zombie proteins! Originally thought to be dead evolutionary remnants, #pseudokinases have since been revealed to play remarkably diverse noncatalytic roles in biological pathways. 🧟♂️ Learn more in this #JBiolChem review: https://t.co/o3Qy6oqKNt.
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Berkshire Hathaway’s Q3’25 filing, Warren Buffett’s pre-ultimate quarter of disclosures, highlights 4 BIG MOVES: • New $3.7B stake in $GOOGL • Cuts to $AAPL, $BAC, $VRSN • Big add to Chubb $CB • Equity allocation still near 3-year lows More below 👇
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New in JBC press: "Identification of a novel GREMLIN1 uptake pathway in epithelial cells that requires BMP binding." Learn more: https://t.co/CpCgYOnkNH
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New in JBC press: "Scientists explored the transcriptional responses of islets to endogenously produced cytokines following immune stimulation with the bacterial pathogen-associated molecular pattern lipopolysaccharide." Learn more: https://t.co/FpV6LHYZJt
#jbiolchem
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Our most recent work has been published in JBC @jbiolchem Congrats to the team! https://t.co/X80S1si4FF
jbc.org
Inhibition of purinergic signaling in cancer has recently received great attention. The purinergic ecto-enzyme CD73 represents a prominent candidate, however its intrinsic role in colorectal cancer...
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Following our previous reports on battle b/w #Leishmania & #Nramp1 for #iron,now @jbiolchem mechanisms from @rupak_iiserk lab-how #Leishmania GP63 alters #macrophage hepcidin. Exciting https://t.co/BtjdlP3nhT.🎉suman, it was special to work on this project during my PhD @iiserkol
jbc.org
Micronutrient sequestration is a powerful host defense mechanism against intracellular pathogens. A key player in this is Nramp1, which effluxes iron from phagolysosomes thereby depriving the...
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Editors' Picks| Neurodevelopmental disorder mutations in the exchange factor DENN/MADD disrupt activation of Rab GTPases Learn more: https://t.co/MudNQCImwt
#jbiolchem
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⚠️CAUTION: SHOCKING CONTENT The cover-up is always worse than the crime... and this crime is pure evil. This 2-minute clip comes from the verbatim film 'The Grooming Gangs Cover-Up,' which details the heinous acts done to children uncovered at trial. @elonmusk
@DominicFrisby
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Inside @JbiolChem: New research sheds light on the fundamental mechanism of gene regulation by the Mediator complex. ➡️Read "N-terminal half of MED14 is critical for Mediator-RNA polymerase II interaction and the resulting transcription" here: https://t.co/gq2bOKKtcl.
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New in JBC press: "Pathogenic variants in KCTD1 disrupt cAMP signaling and cellular communication associated with developmental pathways." Learn more: https://t.co/J94H0yd3Zf
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It’s #WorldCRISPRday! To celebrate, revisit this @jbiolchem review: https://t.co/jezoqEBCat. Tina Liu & Jennifer Doudna explore how Class 1 CRISPR-Cas systems are expanding possibilities for DNA/RNA editing, gene expression control & nucleic acid detection.
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Delve into the importance of evaluating cyanobacterial physiology based on different biomass quantitative units to avoid misinterpretation of results in this JBC paper, a case study of PsbU in Synechocystis sp. PCC 6803 using CRISPRi: https://t.co/1bO663FEKO.
#WorldCRISPRday
jbc.org
Photosystem II (PSII) is a multiprotein complex and plays a central role in oxygenic photosynthesis. PsbU, a 12 kDa subunit of PSII, is associated with thermotolerance and structural stabilization of...
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Inside @jbiolchem | Researchers at Drexel University uncover how the vancomycin-resistant bacterial sensor binds to the antibiotic, offering insights to guide inhibitor design that restores antibiotic effectiveness against hospital-acquired infections. https://t.co/xfJuXnfsuG
asbmb.org
Researchers at Drexel University uncover how the vancomycin-resistant bacterial sensor binds to the antibiotic, offering insights to guide inhibitor design that restores antibiotic effectiveness...
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New in JBC press: "Scientists' data illustrate how the modular nature of these chemokines enables their overlapping but non-redundant functions." Learn more: https://t.co/k3oKDvwiTU
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New in JBC press: "Putative receptors and signaling pathways responsible for the biological actions of epoxyeicosatrienoic acids." Learn more: https://t.co/mSHzs53fa9
#jbiolchem
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JBC: On the cover! This immunofluorescence image of a mouse intestinal organoid highlights successful peptide delivery (green) targeting NHERF4 sequences that regulate GCC activity in the intestinal epithelium. ➡️More in this paper by Ramananda et al.: https://t.co/gL4NPfWExw.
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Happy to share our work on a T6SS effector with ADP ribose cyclase activity, published in JBC @jbiolchem Great work of Julius Martinkus and (always) great collaboration with Dukas Jurenas and @LaurentTerradot
https://t.co/zZeIuRembe
jbc.org
Bacterial polymorphic toxins are modular weapons that mediate intermicrobial competition and host interactions by delivering diverse cytotoxic domains through specialized secretion systems. Here, we...
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New in JBC press: "Scientists identified the heterodimeric amino acid transporter as being responsible for transporting NA-Fe(II) complexes into the vascular system." Learn more: https://t.co/95cHLUdnKX
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