Dr. Holly Hunsberger
@HunsbergerLab
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Assistant Professor (she/her), @RFUniversity / @WestVirginiaU ➡️ @ColumbiaPsych / #SABV / Sex differences in Alzheimer's disease progression / 🚴 Instructor
North Chicago, IL
Joined June 2009
🚨NEW PAPER🚨 Huge congrats to @KamKaplanRFUMS on his first first-author data paper and @Lainey10yes on her first ever publication!! Seriously so proud of this lab always. Summary below (2-4).
link.springer.com
Scientific Reports - Alprazolam induces anterograde amnesia for contextual fear memory and alters dorsoventral hippocampal neuronal ensembles in female mice
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Excited to see this work out! Combination therapy could be the future of AD treatments. Loved being a part of this study during my time in the Denny lab bridging the ketamine and AD crews. @BriKChen @DrChristineAnnD #ENDALZ .
alzres.biomedcentral.com
Background Alzheimer’s disease (AD) is the leading cause of dementia. There are limited approved medications that delay cognitive decline or lessen neuropsychiatric symptoms. Numerous clinical trials...
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RT @josie_mcgowan: We need to talk about the effects of US science funding cuts on the lives of scientists and on the future of discovery &….
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My favorite is the Summer lab explosion. I’m always impressed with the passion and new ideas from our summer interns and volunteers!! Thanks Tala Coffee Roasters for an awesome lab meeting space ☕️. Not pictured: My orange juice coffee combo 🤯.
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We are now examining the role of interneurons in this circuit (SST!) and how repeated use impacts aged and AD mice.
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Here, we examine the acute effects of Xanax on fear memory and activated neuronal ensembles. With a single injection, we found memory impairment in both males and females and alterations in hippocampal encoding and retrieval cell activation, specifically in females.
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The aged population is heavily prescribed benzodiazepines (BZDs) for treatment of anxiety, but BZD use can result in memory impairments. While BZDs can be beneficial, long-term use might not be helpful in a population at risk for memory decline and Alzheimer's disease (AD).
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RT @sarah_stern: Reminder: if you’re a scientist whose funding has been cut or impacted, I would love to interview you for a podcast I’m wo….
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Each of us is a complicated web of emotions! @pixarinsideout @Lainey10yes @KamKaplanRFUMS @SashaFeshchenko #memoryengram #corememory #HappyHalloween
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First @SfNtweets for the Hunsberger Lab! Go say hi and talk science with this awesome crew 👇🏻 #proudPI #RFU @Lainey10yes @KamKaplanRFUMS
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RT @Michelle_Jin1: Disease-modifying anti-amyloid beta treatments are becoming an essential part of neurologists’ repertoire for treating A….
eneuro.org
A new era of disease-modifying therapy for Alzheimer's disease (AD) arrived in 2021 following the Food and Drug Administration's (FDA) decision to grant accelerated approval for aducanumab, an...
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Excited to finally share this labor of love! This was a huge team effort. Thanks to everyone involved, Christine for believing in it, the @NIHAging for funding, Dr. Seonjoo Lee for making my translational dream come true, and all the students who helped analyze brain images 🙏.
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RT @Zuloaga_Lab: 📣We are hiring!!!. Postdoc and technician positions available! . See our website for details:. Pl….
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“The Real Cotsx” 😂 very entertaining lab meeting today. #newmascot.
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🥹.
Listening to @DrGlitterbear speak at the inaugural Society for Behavioral Neuroendocrinology Online Research Symposium #SBNORS .I can't begin to explain the thrill I'm experiencing as an animal scientist now in a neuroscience lab studying sex differences!.
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Thank you for an awesome and stimulating talk!.
Leaving Chicago after a brief visit for a seminar @RFUniversity . Had such great time talking to faculty & trainees —many thanks to @HunsbergerLab for the invitation! Great meeting @Lise_Eliot & all, such nice environment! Also managed to see city & friends!❤️
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RT @dabrowska_lab: New lab preprint🥳🧠: The effects of vasopressin (AVP) and oxytocin on BNST excitability and behav….
biorxiv.org
Interoceptive signals dynamically interact with the environment to shape appropriate defensive behaviors. Hypothalamic hormones arginine-vasopressin (AVP) and oxytocin (OT) regulate physiological...
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RT @FrickKaryn: Don't miss your chance to present at MCCS in Chicago! Abstract submission and early registration deadline is this Monday, S….
event.fourwaves.com
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RT @huckinstitutes: A research team led by senior author @J9Kwapis has identified an enzyme that contributes to age-related impairments in….
psu.edu
Memory updating is impaired in old age, yet little is known about the mechanisms behind the process and what goes wrong with older age. A team of researchers from Penn State found that blocking a...
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RT @NeuroEndoAWF: What a great Friday to register for and submit an abstract to a completely free, online symposium! Just 20 days until the….
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