HeuckLab
@HeuckLab
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Official Heuck Lab account. Opinions are only mine.
Massachusetts, USA
Joined July 2018
Small thread on #membranecomplexity #lipiddomain #lipidraft .1/3 Considering the intricate and diverse composition of biological membranes, any attempt to define lipid rafts merely adds confusion when compared with the simpler definition of lipid domains.
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RT @owl_posting: What could Alphafold 4 look like? (Sergey Ovchinnikov, Ep #3). 2 hours listening time . (links below). To those in the (ma….
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Read the full letter from universities opposing 'government intrusion'
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Happy to share our latest work from the lab published in Biochemistry @ACSPublications, @DBS_IISERM. @IiserMohali. Mechanistic Cooperation of the Two Pore-Forming Transmembrane Motifs Regulates the β-Barrel Pore Formation by Listeriolysin O | Biochemistry
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CryoEM structure of the Clostridium perfringens epsilon pore-forming toxin (PDB code: 6RB9) #scivis #molecularart @dzine_ai @proteinimaging .
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Delighted to share this collaborative study with @SANTANU03277687 and his group in Journal of Material Chemistry B, studying pore-forming toxin action at aqueous-liquid crystal interface.
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RT @CostaT_Lab: With @jrpenades, we challenged AI co-scientist @GoogleAI to generate hypotheses. In just 2 days, it recapitulated our unpub….
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RT @Structure_CP: Online now! High-resolution cryo-EM analysis visualizes hydrated type I and IV pilus structures from enterotoxigenic Esch….
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Structural basis for the pore-forming activity of a complement-like toxin | Science Advances #poreformingtoxins.
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Actinoporin Fav bind to cholesterol clusters: Cryo-EM structures of a protein pore reveal a cluster of cholesterol molecules and diverse roles of membrane lipids #poreformingtoxins.
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Cholesterol cluster as PFO binding site, back 2010. The cholesterol-dependent cytolysin family of gram-positive bacterial toxins #poreformingtoxin
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New review out today in Nature Biotech on nanopore-based protein sequencing. Feels. like. something. coming. soon. 👀
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RT @GAnderluh: Protein-Membrane Interactions! . The course of @MOSBRIeu project focuses on studies of protein-membrane interactions by usi….
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A conceptual framework for understanding phase separation and addressi.
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Protein sequencing is key to understanding cellular signalling pathways and metabolic processes. In their Review, @cees_dekker et al discuss how nanopores enable single-molecule protein sequencing and the identification of post-translational modifications.
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Does anyone know if AlphaFold predictions can be improved by providing a better MSA input? #AlphaFold #bioinformatics.
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RT @IsmaelMingarro: #OpenAccess journal @eLife will lose its ‘impact factor’ over controversial publishing model | Science | AAAS https://t….
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