Henry Ford Hypertension and Vascular Research
@HFHypertension
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Hypertension and Vascular Research Division (HVRD), Henry Ford Health System Posts by @313Oz @CardiorenalRese and @m_mendez_313 Unofficial account
Detroit, MI
Joined May 2019
Dr. Paulo Caceres, Ph.D. @Paulo96311850, from our division has been named PI in two federal grants from NIH. Both starting in August 2023, a five-year R35 award from #NIGMS and a three-year R21 #award from #NIDDK, will study epithelium-microvasculature interaction in the #kidney.
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Congratulations Sumit Monu @SumitRa51243775, @313Kidney! Reduced GFR in hypertensive adult ALMS1 KO Dahl SS rats is associated with lower interstitial hydrostatic pressure, higher tubuloglomerular feedback sensitivity, and #glomerular damage/#proteinuria.
journals.physiology.org
Inactivating mutations in the ALMS1 gene in humans cause Alström syndrome, characterized by the early onset of obesity, insulin resistance, and renal dysfunction. However, the role of ALMS1 in renal...
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Congratulations on the R35 grant, Dr. Caceres! @HenryFordHealth @GradPhysiology.
Really excited about our newly funded project to study mechanisms of polarity in proximal tubule and other epithelia. Thank you @NIGMS!! Many thanks to @313Kidney and @HFHypertension for all the support!!
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RT @JAHA_AHA: Patients with difficult‐to‐control hypertension despite optimal medical therapy and following a low salt diet have elevated l….
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RT @313Kidney: @JAHA_AHA @HFHNephFellow Congrats Dr Kausik Umanath and team in @HFHypertension @HFHNephFellow and TCRC @HenryFordHealth on….
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Hamid Suhail and colleagues present a new study: increased bioavailability of endogenous Ac-#SDKP caused by knocking out ACE-N improves LV #cardiac function in mice post-MI, which is likely mediated by minimally reduced expression of #SERCA2. @NourRhaleb.
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New research article alert! The role of cGMP-dependent increase in #NKCC2 #ubiquitination is mediated by the #Cullin-RING E3 ubiquitin ligase in Sprague Dawley TAL epithelium. Congratulations, Dr. Gustavo Ares! #kidneyInCVD @HFHypertension @GradPhysiology
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Congratulations, @Mottillo_Lab! The review covers:.·Adipose Tissue as a Modulator of Energy Homeostasis.·Metabolic Redox Reactions in Thermogenic Adipose Tissue.·Manipulating Adipose Redox Mechanisms as Potential ·Metabolic Disease Therapies.·Conclusions and Future Perspectives.
Our review is now online that explores redox mechnisms in adipose tissue and their thereapeutic benefits. Led by Ashley Putman. Thermogenic Adipose Redox Mechanisms: Potential Targets for Metabolic Disease Therapies #mdpiantioxidants via @antioxidants_OA.
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RT @Mottillo_Lab: Our new paper is live now in Cell Reports Methods! A FRET sensor for the real-time detection of long chain acyl-CoAs and….
cell.com
Mottillo et al. develop a single-molecule FRET sensor based on the ligand-dependent interaction between ABHD5 and PLIN5. The sensor reports intracellular long-chain acyl-CoA (LC-CoA) levels and...
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Overexpression of EP3 in the cardiomyocytes reduces cardiac function under basal conditions (increased cardiac hypertrophy, interstitial collagen fraction, macrophage, and T-cell infiltration) and this is exacerbated after myocardial infarction #prostaglandin.
Please to announce our manuscript was accepted in Life Sciences.
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Please join us in congratulating Bipradas Roy who successfully defended his dissertation today!.Congratulations Bipradas and congratulations to your mentor, Dr. Suresh Palaniyandi! @GradPhysiology @WayneGradSchool @HenryFordHealth.
Tune in tomorrow to hear some exciting new science from Bipradas Roy's public dissertation defense. Good luck Bipradas! @HFHypertension @GradPhysiology @WSUResearch @Punom0173726079
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Heart walk and 5K was a success. We put in some work. Thanks everyone for coming out! #DetroitHeartWalk @HFHypertension
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Support the Metro Detroit Heart & Stroke Walk on Saturday! This effort provides awareness and raises much-needed funds for heart disease and stroke research, as well as educational programs for our community. Our coach - Tim Bryson @tbryson9690 @HeartNews.
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RT @AJPRenal: ✨CONGRATULATIONS!!! #AJPRenal May #APSselect article "Decreased #tubuloglomerular feedback response in high-fat diet-induced….
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Congratulations @SumitRa51243775 . !.Decreased tubuloglomerular feedback response in high-fat diet induced #obesity #kidneyInCVD #glomeruli.
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𝑹𝒆𝒔𝒆𝒂𝒓𝒄𝒉 𝑨𝒔𝒔𝒊𝒔𝒕𝒂𝒏𝒕 𝒑𝒐𝒔𝒊𝒕𝒊𝒐𝒏 𝒐𝒑𝒆𝒏 in the Caceres lab (Epithelial Biology/ Kidney Physiology). Offered to trainees interested in pursuing a Ph.D. or M.S. degree, or to gain experience in laboratory research. #sciencejob.
henryford.referrals.selectminds.com
Under general supervision and following established policies and procedures, performs experiments related to specific research projects and...
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Lisinopril lowers BP and increases anti‐fibrotic biomarkers in African Americans with left ventricular hypertrophy.@cesarom1 @HFHypertension @WSUResearch @waynemedicine #iBio
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Great news, congratulations! @HenryFordNews @WSUResearch.
Today is NoA day! Excited to get this project that investigates the mechanisms of NAFLD going. Thank you to @NIDDKgov for their support.
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