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Guillermo Acuna Lab Profile
Guillermo Acuna Lab

@GuilleAcuna_Lab

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Interdisciplinary team of researchers @unifr exploring the potential of DNA nanotechnology to fabricate optical antennas to control light at the nanoscale

Fribourg, switzerland
Joined September 2020
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@GuilleAcuna_Lab
Guillermo Acuna Lab
1 year
What do the freezing process and the 2022 Nobel Prize in Chemistry have to do with the functionalization of nanoparticles ... and why would it matter? Check out our latest work out in @J_A_C_S https://t.co/9FUryKzjzk in collaboration with @HiroshiSug61443 and Denis Garoli. 1/4
pubs.acs.org
Nanotechnology has revolutionized the fabrication of hybrid species with tailored functionalities. A milestone in this field is the deoxyribonucleic acid (DNA) conjugation of nanoparticles, introdu...
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@Guille_P_Acuna
Guillermo Acuña
1 month
🔬📱 Direct single-molecule detection and super-resolution imaging with a low-cost portable smartphone-based microscope. Our latest work published in Nature Communications. https://t.co/hxOZw7aNaE
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nature.com
Nature Communications - Loretan and colleagues present a low-cost smartphone-based microscope capable of detecting single-molecule fluorescence. This approach opens doors to personalised and widely...
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@FerStefaniLab
Fernando Stefani Lab
1 month
Two new advances from our group in collaboration with @GuilleAcuna_Lab expand the realm of super-resolution microscopy and single-molecule measurements: Small Methods - https://t.co/syRPvGbEU2 Nature Communications - https://t.co/GFJPsCXk8x 👇👇👇
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nature.com
Nature Communications - Loretan and colleagues present a low-cost smartphone-based microscope capable of detecting single-molecule fluorescence. This approach opens doors to personalised and widely...
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@GuilleAcuna_Lab
Guillermo Acuna Lab
2 months
It was great to meet @HiroshiSug61443, our longtime collaborator on all things silicon. 🎉 He gave an informal talk, and we also had the chance to share our work with him. Always inspiring to exchange ideas and catch up in person! @unifr @UnifrPhysics
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@HiroshiSug61443
Hiroshi Sugimoto
2 months
It was a great visit to @GuilleAcuna_Lab at Fribourg. Many thanks to Guillermo for his warm hospitality. We exchanged many ideas for collaboration and even enjoyed a real cheese fondue together.
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@LightSciAppl
LightSciAppl
3 months
#LSA_Highlight: [Research Article] Wide-field fluorescence lifetime imaging of single molecules with a gated single-photon camera. @EPFL_en @iiscbangalore @unifr #Fluorescence_resonance_energy_transfer #Wide-field_fluorescence_microscopy https://t.co/sLQDqOUjrU
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nature.com
Light: Science & Applications - Wide-field fluorescence lifetime imaging of single molecules with a gated single-photon camera
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@FerStefaniLab
Fernando Stefani Lab
4 months
Con gran alegría anunciamos la segunda edición del taller de formación en microscopías de super-resolución FOMISUR 2025. Becas a través de la Red Federal de Microscopía de Super-resolución https://t.co/WO11hvIgID
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@HiroshiSug61443
Hiroshi Sugimoto
4 months
After the first day of our special session in META that I am co-organizing, we went out for dinner. It was a wonderful Spanish meal.
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@GuilleAcuna_Lab
Guillermo Acuna Lab
4 months
Glad our paper found a home in Small Structures @AdvPortfolio! Thanks to Maria Sanz-Paz, Javier González-Colsa, Guillermo Serrera, Minoru Fujii, Hiroshi Sugimoto (@HiroshiSug61443), Pablo Albella, the Acuna lab for the great collaboration! @snsf_ch for funding & @UnifrPhysics
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@GuilleAcuna_Lab
Guillermo Acuna Lab
4 months
These findings push forward new possibilities for designing nanophotonic platforms that preserve or even enhance fluorescence emission without introducing significant non-radiative losses. Read our full paper at: https://t.co/OhyNnl5ivd Congratulations to everyone involved!🥳
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@GuilleAcuna_Lab
Guillermo Acuna Lab
4 months
✨ We found: 1. Absence of fluorescence quenching - even at short distances! 🤯 2. Strong radiative enhancements 3. High quantum yield preserved This is in contrast to metals, where, losses are the main source of decay at shorter distances.
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@GuilleAcuna_Lab
Guillermo Acuna Lab
4 months
We precisely positioned single emitters near individual Silicon NPs at varying distances using DNA origami 🧬(our nanoscale ruler). Then, we measured fluorescence lifetime, fluorescence intensity, and extracted the radiative & non-radiative decay rates as a function of distance.
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@GuilleAcuna_Lab
Guillermo Acuna Lab
4 months
Enter: Silicon NPs. High-index dielectric nanoantennas that offer negligible ohmic losses, support both electric and magnetic resonances in the visible and near-infrared range. But do they really work at the single-molecule level? We put them to the test with DNA origami 🧬
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@GuilleAcuna_Lab
Guillermo Acuna Lab
4 months
💡 New paper alert! Metallic nanoparticles (NPs) have long been used for enhanced spectroscopies, sensing & imaging due to their unmatched electric field enhancements. But there's a catch: - Fluorophores near metals often quench - Metals suffer from ohmic losses Alternatives?
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@HiroshiSug61443
Hiroshi Sugimoto
4 months
I’ll be leaving Japan soon and heading to Spain for META 2025 next week and give an invited talk on chirality transfer in Si nanoparticle composites. I'm also excited to co-organize a special session together with @GuilleAcuna_Lab and Peter Zijlstra.
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@ssimoncelli
Sabrina Simoncelli
6 months
🚨 New paper alert! 🚨 Can we simultaneously achieve deep, high-res, large field-of-view imaging without the usual trade-offs? 🤔 🧬🔬 YES: #DNA_PAINT + Spinning Disk Confocal + Optical Photon Reassignment (#SDC_OPR)! #SuperResolution 📄 https://t.co/YKYgcDyMLG @NatureComms 🧵👇
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nature.com
Nature Communications - Zaza and colleagues demonstrate that DNA-PAINT on a spinning disk confocal microscope with optical photon reassignment enables high-resolution imaging across large fields...
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@GuilleAcuna_Lab
Guillermo Acuna Lab
6 months
Many thanks to @ssimoncelli and the whole team for this excellent work! In this collaborative effort, we show a powerful tool for imaging complex biological systems and push super-resolution imaging to new limits and achieve sub-10 nm precision across large FOVs
@ssimoncelli
Sabrina Simoncelli
6 months
🚨 New paper alert! 🚨 Can we simultaneously achieve deep, high-res, large field-of-view imaging without the usual trade-offs? 🤔 🧬🔬 YES: #DNA_PAINT + Spinning Disk Confocal + Optical Photon Reassignment (#SDC_OPR)! #SuperResolution 📄 https://t.co/YKYgcDyMLG @NatureComms 🧵👇
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@GuilleAcuna_Lab
Guillermo Acuna Lab
6 months
and deep into tissues. Looking forward to the exciting new processes we can study using this! #DNAOrigami #DNAPaint #SuperResolutionImaging
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@GuilleAcuna_Lab
Guillermo Acuna Lab
6 months
Many thanks to @ssimoncelli and the whole team for this excellent work! In this collaborative effort, we show a powerful tool for imaging complex biological systems and push super-resolution imaging to new limits and achieve sub-10 nm precision across large FOVs
@ssimoncelli
Sabrina Simoncelli
6 months
🚨 New paper alert! 🚨 Can we simultaneously achieve deep, high-res, large field-of-view imaging without the usual trade-offs? 🤔 🧬🔬 YES: #DNA_PAINT + Spinning Disk Confocal + Optical Photon Reassignment (#SDC_OPR)! #SuperResolution 📄 https://t.co/YKYgcDyMLG @NatureComms 🧵👇
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@FernaStefani
Fernando Stefani
6 months
#cientificidio El gobierno de Milei ha implementado una política de aniquilación de la ciencia. El mie 28/5 se marcha en todo el país. En CABA Polo Científico Tecnológico, Godoy Cruz y Paraguay 13 hs. Vengan todos a defender la ciencia argentina. NADIE SE SALVA SOLO.
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@FernaStefani
Fernando Stefani
7 months
10 de abril - Día del Investigador Científico en honor a Bernardo Houssay. Ni homenaje, ni respeto. Desprecio e ignorancia.
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clarin.com
El gobierno de Javier Milei paralizó proyectos, desfinanció universidades y redujo a una subsecretaría sin presupuesto la política científica nacional. Equipos se destruyen, jóvenes emigran y el...
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