
Ewan Gerken
@EwanGerken
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PhD Candidate @ The University of Adelaide Doing cool neuroscience stuff with zebrafish ππ§ π¬
Joined June 2021
Excited to release a preprint on our MPS III #Sanfilippo syndrome zebrafish! ππ§ super interesting results in our quest to understand this disease and help children and families living with childhood dementia! . Thanks to @SFCFoundtn for their vital support of this project!.
Zebrafish models of Mucopolysaccharidosis types IIIA, B, & C show hyperactivity and changes in oligodendrocyte state #bioRxiv.
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Media release from the @SFCFoundtn giving an update on our work. Interesting findings, however we have lots more to learn! ππ¬π¨βπ¬.
Project Update: A/Prof Michael Lardelli from @UniofAdelaide & team have completed their Incubator project funded by @SFCFoundtn to develop 3 new zebrafish models of #Sanfilippo & undertake behavioural & transcriptomic analysis: #ChildhoodDementia @ADandCD
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A story from the ABC on the impact and challenges of #Sanfilippo syndrome for families. Pretty clear that more research into #childhooddementia is needed! π§ π¬.
abc.net.au
Families say childhood dementia is underfunded and under-researched and they want greater public awareness to help improve their children's short lives.
You might know of dementia as mainly affecting older Australians, but in rare cases, it also affects children. Families say childhood dementia is underfunded and under-researched, and they want greater public awareness to help improve their children's lives. #abc730
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Thanks to The #Sanfilippo Children's Foundation for asking me to appear on their website π here I give some insights into my research motivations and hobbies outside of the lab π¬π§ β½οΈπ definitely need to work on my photogenicity though π. #researcherprofile.
Ewan Gerken is a PhD Candidate at The University of Adelaide who uses zebrafish models of Sanfilippo and early-onset Alzheimerβs Disease to study how these diseases affect the brainβs cells and zebrafish behaviour. Read more about his work:
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Yesterday was World #Sanfilippo Awareness Day! In true PhD student fashion I was in the lab until 10pm ππ§ͺ however on my way home I managed to grab this late night pic of Adelaide Oval lit up beautifully in support of Sanfilippo syndrome π to learn more head to @SFCFoundtn
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I can say from sitting next to him every day that Lachie has put immense effort into making this an elegant and efficient package! π. @baerlachlan can I claim authorship for helping with the name? π§.
tadar is now available with the release of Bioconductor 3.18! My first R package and another one for @stevie_ped π₯³ tadar enables Differential Allelic Representation analysis, improving our inferences from RNA-seq data in non-isogenic organisms. More info:
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RT @Dr_Meming: When somebody asks if youβve figured out what you want to do after your PhD
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We at the Lardelli lab are big fans of cost efficiency π€©.
Got sick of buying PCR enzymes so we made our own! 100 mLs of taq that's going to last us years! @AcademicChatter
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RT @BrownRyan97: Congratulations @EwanGerken & authors! An awesome preprint that uses zebrafish to model the #RareDisease, Sanfilippo Syndrβ¦.
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RT @baerlachlan: Woohoo! Our lab's first manuscript of Sanfilippo syndrome zebrafish models. Lots of information on the generation and chaβ¦.
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Thanks to Dr. Syahida Ahmad at @uputramalaysia for her early work on this project, and especially to senior authors @kariisssaaa at @Flinders and Assoc. Prof. Michael Lardelli at @UniofAdelaide.
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The @SFCFoundtn do amazing work not only for families and children living with #Sanfilippo, but by funding important research and supporting young students such as myself. Very appreciative of this opportunity! π§ π.
We are proud to award a PhD top-up scholarship to @EwanGerken at @UniofAdelaide. Based in A/Prof Michael Lardelliβs lab, Ewan will use zebrafish to investigate the molecular changes in #Sanfilippo & compare results to early-onset #Alzheimerβs Disease:
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Cool to see the hard work from Karissa and myself is showing promising results! ππ§ .
Hot off the press! Our #sanfilippo model #zebrafish accumulate heparan sulfate in their brains, just like children who live with this disease. Our zebrafish will be used to find new treatments for this devastating disease @SFCFoundtn
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