Chad Johnston
@EvolvedChem
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Assistant professor and CPRIT Scholar at the Baylor College of Medicine in Houston, starting Jan 2022. Discovery and directed evolution of natural products ðŸ¦
Houston TX; Previously Toronto
Joined July 2020
Happy to finally be announcing that I’ll be joining the Baylor College of Medicine as an assistant professor and CRPIT scholar starting January 2022!
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Well, it took a little longer than expected, but we're happy to share our lab's first paper. Thanks to the reviewers and editors at JACS for sticking with us through a surprisingly weird story 😅. Science never changes.
pubs.acs.org
Antibiotics are essential for modern medicine, but their use drives the evolution of antimicrobial resistance (AMR) that limits the long-term efficacy of any one drug. To keep pace with AMR and...
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It's not necessarily science, but I'm exposed through my better half. Kyla Scanlon is the best finance follow out there.
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A new paper from Kim Lewis identified a natural product Evybactin targeting DNA gyrase and killing Mycobacterium tuberculosis via a selective transport mechanism. Free to read link at https://t.co/3hOB9XYKRa
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First Johnston lab outing! Great time with the team, plus I learned I can't take group selfies AND look normal. Maybe one day.
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Me - a new PI with a freezer already full of bacterial extracts
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Hey aspiring PIs! Looking for a Prof position that comes with a cool neighbour? My department is hiring ! Come see everything Baylor, Houston, and the Texas Med Centre have to offer! (spoiler: it's a lot) https://t.co/bWz4HViZAy
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Taste the Streptomyces rainbow (but really you probably shouldn't even if it's BSL1... but maybe?)
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Rolf Müller remains the king of microbial natural products IMO. Another paper on a cool new antibacterial NP from Myxobacteria. Really looking forward to learning the target for this one!
Preprint: Structure elucidation, biosynthesis, total synthesis and antibacterial in-vivo efficacy of myxobacterial Corramycin.
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Excited to share our most recent work in @NatureComms, a collaboration with @NUSynBio labs @DTElab @jewettlab_NU @monicagroup and the Mangan lab. We set out to investigate the role of bacterial organelle morphology on encapsulated pathway performance https://t.co/69TK6bMS3D (1/9)
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Work by @simonsnitz, @alperlab, Andy Ellington & colleagues evolves a general transcription factor into specific biosensors for various alkaloids, enabling streamlined production of tetrahydropapaverine. Free to read link at https://t.co/gwnzQl9An3
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Are you interested in host-microbe interactions and women's health? We're hiring a full-time research technician to work with us in balmy Houston. We have fun people, cool science, and air conditioning! @BCMFromtheLabs #Houston #GraduateJobs
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Hey you! Yeah, you in the corner! are you interested in light perception? Then let me borrow your attention to talk about our new publication in @CurrentBiology about light sensing in Fungi and how we show that the fungal ancestor could sense light! 👇 https://t.co/l85CpTEJFu
cell.com
Galindo et al. demonstrate that a light response circuit, which controls swimming behavior, is present across diverse fungi. The circuit functions in coordination with a lipid-filled subcellular...
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Hey Internet! @AhmedHBadran and I have released a review on natural products (and non-natural, if that's your thing) that function as precision antibiotics - something both our labs will be exploring in the next few years. Link! https://t.co/O1WHQy4GZD
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Interested in new biosynthetic strategies to make toxic small molecules? Here you go, our work on cyanobacterin biosynthesis now out @nchembio! Congrats to @pmdagostino, coauthors and collaborators @biomicat! Thanks @tudresden_de @TUD_Science, our home!
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Please RT: I have two immediate postdoc openings: 1. Engineering synthetic human chromosomes (funded by @wellcometrust to work with Jason Chin and @ProfTomEllis ); and 2. Engineering synthetic yeast genome and speciation (funded by @VolkswagenSt to work with @LarsMSteinmetz )
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We are hiring !! Looking for a motivated and enthusiastic research technician to join our lab. We study the link between the gut microbiome and immune dysregulation. Check out the full details
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Twitter, lend me your re-Tweets! Our lab is looking for a research technician in bacterial molecular & synthetic biology🦠. If you're finishing your BSc and wanted to try your hand at evolving antibiotics, we're the lab for you! https://t.co/rr9ReiHDYX
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