🌈This Pride Month, we sat down with @LukeFlower1 proud member of the LGBTQ+ community, to hear his story. At the VPD-HLRI, we’re proud to celebrate voices like Luke’s and to stand for inclusion, visibility, and equality every day of the year. 🏳️‍🌈 #PrideMonth #Pride2025

I'm honoured to be awarded the BSI career enhancing grant to investigate neutrophil innate immune training. Many thanks to BSI and to my supervisor @charlot_summers for her help and support!

Had a great couple of days in Newcastle for the first time at the UK Neutrophil conference with my colleagues @EmilioVozza & @ZhenguangZhang from the @HLRI_Cambridge.

🔓 Our review on inflammasomes in ARDS 🏥 ARDS treatments are limited 🫁 Multiple inflammasomes drive ARDS via IL-1β/18 💊 Their modulation offers potential therapies 🔬Human-specific research is needed @charlot_summers @EmilioVozza @ClareBryant13 https://t.co/xbGi3C5jPl

Role of inflammasomes in acute respiratory distress syndrome https://t.co/yHiYaWvBl3 @LukeFlower1 @EmilioVozza @ClareBryant13 @HLRI_Cambridge

Thanks for all the kind messages today about my appearance at the #CovidInquiry. More to be said in evidence in the coming days (we stopped unexpectedly early today), but the report Ganesh and I wrote is now publicly available for anyone interested: https://t.co/g0viGYEz3M

Join us this Friday for #EuropeanResearchersNight in @tcdTBSI and learn how to train your immune system to beat the bugs! Even try your own hand as a part of our pest patrol team to see how well you can defend yourself against bug invasion!🦠🧬🦠 #startatern #irishresearch

‼️New paper alert‼️ Our review exploring the ageing immune response in disease and the potential of the Nrf2-HO-1 axis as a therapeutic target is now available online at @FrontImmunol #irishresearch #ageing #immunology

4) Together, we highlight the importance of IFN-I in facilitating S. aureus nasal colonisation and the role that phagocytes play in restricting this notorious opportunistic pathogen and important human coloniser!

3) Loss of IFN-I removes trail and daxx expression and significantly reduces apoptosis of phagocytes in the nasal cavity, leading to enhanced clearance of S. aureus in colonised mice.

2) we show that S. aureus induces IFN-I in a strain dependent manner, leading to the upregulation of the apoptotic factors trail and daxx culminating in caspase-3 cleavage.

I'm thrilled to share my recent publication with the amazing @McLoughlin_Lab and team! Together, we show that S. aureus can drive IFN-I dependent apoptosis in phagocytes to enhance nasal colonisation! https://t.co/kjoVvjVoTN

Type 1 IFN promotes Staphylococcus aureus nasal colonization by inducing phagocyte apoptosis @McLoughlin_Lab https://t.co/y83Ufcb0yM

Would highly recommend doing a PhD in the host pathogen interaction lab. Rachel is a superb supervisor with an amazing lab, and I am so happy to have done my PhD with her and the team!

Wellcome Trust Discovery Award of €5.3 million to investigate leading global cause of fatal bloodstream infection granted to APC & @UCC @ProfRuthMassey along with @McLoughlin_Lab - @tcdTBSI and researchers from @UniofExeterSE & @bristoluni Read More: https://t.co/fFsMXOrZv3

I am so delighted to see my paper out in the world! We show that S. aureus drives glycolysis, limiting the pentose phosphate pathway to inhibit neutrophil function and facilitate its intracellular survival. Many thanks to my supervisor @McLoughlin_Lab & to my amazing Co authors!

#EMDS2022 was absolutely stellar! Great talks from so many amazing researchers. Glad to be apart of it and have the chance to share my own work.

Great lab day out yesterday ⁦@goquestdub⁩ a convincing win by team Superbugs but a valiant effort by the Staph day out team

Learning more about how this crafty bacterium shapes host immunity. Latest work from the lab initiated by ⁦@john_leech07⁩ but brilliantly developed by talented PhD student Alanna Kelly #hostpathogeninteractions ⁦@tcdbi⁩ ⁦@tcdTBSI⁩

Huge congratulations to our two #ECMConf22 poster prize winners: @pablo_relucio and Cliodhna Daly!🎉 These poster prizes were sponsored by #AccessMicro, our sound science, #OpenAccess research platform. Find out more and publish with us today: https://t.co/0ppB6Un50z