Dr. Mehroosh Shakeel | FRCPath, FCPS
@Drsurgicalpath
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Surgical Histopathologist @FatimaMemorial1 | Ex-Fellow & Resident (Histopathology) @SKMCH | Interests: Breast, Gynae, H&N Pathology | Traveler & a Foodie
pakistan
Joined March 2011
Behind the pink ribbon, thereโs a story only a histopathologist can reveal. *Early detection saves lives*. ๐ #PinkOctober #BehindTheScenesOfBreastCancerDiagnosis
#BreastCancerAwarenessMonth
#breastpath
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Welcome back to Breast Consult Case of the Week 10 #BCCW10! This one was tricky, and I apologize for leading you astray by not giving you the whole IHC panel, but this is exactly the kind of situation where serious misdiagnoses will happen. The correct answer is
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Amazingggg !!!
Cytology Search Engine: https://t.co/TCRvobnQXn Searches time-stamped lecture videos and texts. ๐ If you find this helpful (or not ๐), comment below! #Cytology #Pathology #Python #PathTwitter #Cytopath
https://t.co/xMcylOIimO
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Breast - Post Neoadjuvant Chemotherapy resections What is the significance of Residual Disease? - No residual disease (pCR): Continue any planned therapy - Residual disease: Add-on therapy, see pic below Dr. Bean - 2025 Contemporary Issues in Breast Pathology #USCAP #pathology
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Breast - Postneoadjuvant chemotherapy Intraoperative lymph node evaluation - Up to 40% of patients convert to node negative - Frozen section: High false negative rates and false positive pitfalls exist. - Avoid overcalling something that you are not sure is carcinoma.
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Breast- Neoadjuvant chemotherapy Tumor Bed- Stromal Changes - Fibrosis - elastosis - Prominent vessels - Fewer to absent normal epithelial structures - Inflammation - Hemosiderin - Calcifications Dr. Bean - 2025 Contemporary Issues in Breast Pathology #USCAP #pathology #PathX
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Breast - Postneoadjuvant chemotherapy specimens Only residual LVI? - It is not pathologic complete response (pCR) - It is rare - Mostly associated with poorer outcomes - AJCC does not account for this scenario. It is not clear how to stage it, it could be helpful to write a
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Malignant phylloides tumor with liposarcomatous differentiation. Note striking pleomorphic lipoblasts. #Pathology #breastPath #malignant_phyllodes
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๐ก The future is here โ and itโs collaborative, data-driven, and deeply human #Research
#AIinHealthcare #InnovationInAction #histopathology #pathology #teamwork #MedicalEducation
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As co-author, proud 2 share our Carcinosarcoma study won 1st prize at FMH NUR-FMS Research Conference 2025. Kudos to our brilliant residents! โจ A big congrats 2all the participants,mentors& organizers fr setting a new benchmark fr integrated health sciences research in Pakistan!
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Do you know how to FISH? I am delighted to share our 20+ years of experience with FISH, just published in @Human_Pathology (PMID: 40782985) - ย Everything You Need to Know About FISH! This comprehensive review covers the full spectrum of fluorescence in situ hybridization (FISH)
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Breast-What about the term Invasive Papillary Carcinoma (IPC)? WHO 6th edition (expected change-not published yet) - Most cases reported as IPC are in fact Encapsulated Papillary Carcinomas (EPC) or Solid Papillary Carcinomas (SPC) or mets - Carcinomas with growth pattern
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Encapsulated Papillary Carcinoma (EPC) almost 100% infacted after core needle biopsy could be misdiagnosed as infarcted intraductal papilloma Lesson: Always evaluate infarcted areas and any residual viable cells Dr. Brogi- Contemporary Issues in Breast Pathology #USCAP
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Tall cell carcinoma with reverse polarity (TCCRP) - Solid and papillary patterns - Immunoprofile is similar to UDH-ER low, CK 5/6 mosaic - Include TCCRP in the differential diagnosis of "papilloma/atypical papilloma" Dr. Brogi- Contemporary Issues in Breast Pathology #USCAP
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It would be quite exciting โจ๐คฉ
๐ง New @PathPod Mini-Series: The Path Less Traveled Was your road to pathology full of unexpected turns? Maybe you came from another career, pursued a completely different field before medicine, or found your way to diagnostics through an unconventional passion - law, art,
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๐ Sharing the learning forward! Our resident recreated key takeaways from the PAP Conference for everyone in the department โ because knowledge grows best when shared ๐ฑ Awsome job, residents! #pathology #MedicalEducation #TeamLearning #PAP2025
#Histopathology
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Breast pathology lecture: 15 Octoberย 09:30 UK time "The Transformative Impact of Molecular Pathology on Breast Cancer Care" Joining Details for all (Path Soc Members and Non- Members):ย https://t.co/oJAyW7htaw The lecture can also be watched live on:ย https://t.co/62uiRXpbg2
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From glass slides to pixels to predictions โ todayโs digital pathology & AI session was ๐ฅ Thanku @Aparwani_dpath and @IbrahimManff Let's start smart. Team up. Learn. Train to bring digital pathology to life in our setup ๐ก #DigitalPathology #PakistanassosciationofPathologist
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Usual Ductal Hyperplasia-helpful HE clues - Nuclei is variable and touch the lumina (pic 1) - Pink intranuclear pseudoinclusions (pic 2) - Nuclear grooves (pic 3) Dr. Cimino-Mattews-Contemporary issues in Breast Pathology #USCAP #PathX #pathology
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๐ Coming Up Soon! ๐จ 2025 ISGyP Annual Meeting Theme: Daily Conundrums in GYN Pathology ๐
Sat Oct 25 - Sun Oct 26 (2 sessions) ๐ป Virtual โ join from anywhere ๐ต Free registration ๐ Earn 4 CME credits ๐ Register now: https://t.co/Q2UBdsDai6
#GynPath #GynaePath #PathTwitter
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We are live from Boston. Trouble distinguishing pancreas carcinoma from chronic pancreatitis? trouble with autoimmune pancreatitis. Look no further. Start time 8:00 AM EST. Frontiers in Gastrointestinal & Hepatobiliary Pathology 2025 https://t.co/4GjaTcVPDa via @YouTube
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