DipeshUpretyMD Profile Banner
Dipesh Uprety MD FACP Profile
Dipesh Uprety MD FACP

@DipeshUpretyMD

Followers
2K
Following
6K
Media
192
Statuses
4K

Associate Prof | Thoracic Oncology 🫁 & Phase-I @karmanoscancer | EIC @BTFCancerNews |Previously @MayoCancerCare @gundersenhealth @JeffHealthAb | Tweets my own

Detroit, MI
Joined June 2018
Don't wanna be here? Send us removal request.
@DipeshUpretyMD
Dipesh Uprety MD FACP
10 months
Pleased to share our study -"Trends in Incidence & Survival Outcomes in Small Cell Lung Cancer Patients" ➡️SCLC cases have gradually declined, now comprising 11.2% of all lung cancers @OncoAlert #LCSM @BTFCancerNews @aniroulaMD @kaushalpar @thadid1 https://t.co/rC5Vy1A578
Tweet card summary image
onlinelibrary.wiley.com
Background There has been a lack of updated epidemiological data on the incidence and survival outcomes for patients with small cell lung cancer (SCLC) in the United States over the last two decade...
4
8
37
@StephenVLiu
Stephen V Liu, MD
6 days
Trainees & junior faculty: the #TexasLung26 Poster Competition is open - winners will receive registration, travel, and accommodation to the 2026 Texas Lung Cancer Conference at Austin City Limits, April 9-11, 2026. Submit today! Details at https://t.co/23wG464LxK
0
7
28
@RManochakian
Rami Manochakian MD, FASCO Cancer Education
11 days
🙏🌟It’s been one of the MOST rewarding experiences of my #Academic Career to serve as the: ❇️#Chair of the #Oncology #Training Programs (OTP) #Committee of @ASCO. My term, during which I worked with AMAZING colleagues & GREAT #ASCO Staff, was completed by chairing the:
16
10
69
@PaulSaxMD
Paul Sax
12 days
Hey ID Fellows, what are your favorite ID consults? Asked that question during a recent visit to the ID division at Johns Hopkins, and here's what their fellows said.
Tweet card summary image
blogs.jwatch.org
Just back from a visit to the Infectious Diseases Division at Johns Hopkins, thanks to the kind invitation of current ID chief Dr. Amita Gupta and her predecessor, Dr. David Thomas. On a personal...
7
12
69
@RManochakian
Rami Manochakian MD, FASCO Cancer Education
18 days
🔥🚨#November is 🫁 #LungCancerAwareness Month. Lung Cancer Awareness #SavesLives. Together, WITH #Patients, we keep the #Fight against #LungCancer. We have made a great #Progress but still have a long way to go. #LCAM25 👇🏼Sharing, like every year, my #AWARENESS #Mnemonic
4
42
74
@RManochakian
Rami Manochakian MD, FASCO Cancer Education
1 month
🔥🚨@OncoAlert Hot Off The Press. Just published @NEJM in conjunction with presentation @myESMO #ESMO25 Results of: 🎯#OptiTROP-Lung04 phase 3 trial of: ⭐️#Sacituzumab tirumotecan (#TROP2 #ADC) VS #Chemotherapy in advanced #EGFR mutant non-small cell #LungCancer after
2
19
59
@RManochakian
Rami Manochakian MD, FASCO Cancer Education
1 month
🔥🚨@OncoAlert Hot Off The Press. Just published @TheLancet in conjunction with presentation @myESMO #ESMO25 Results of: 🎯#HARMONi-6 phase 3 trial of: ⭐️#Ivonescimab + #Chemotherapy VS #Tislelizumab + #Chemotherapy as 1st line Tx for advanced #Squamous non-small-cell
2
34
66
@StephenVLiu
Stephen V Liu, MD
1 month
Dr. Pedro Simoes da Rocha at #ESMO25 presents intracranial efficacy of ifinatamab deruxtecan (I-DXd, B7-H3 ADC) in #SCLC. Intracranial RR 46.2% (among pts with no prior radiation, icRR 57.7% and in pts with no brain mets, only 12.5% had CNS progression. #ESMOAmbassadors
4
25
47
@HHorinouchi
Hidehito HORINOUCHI
1 month
🆙#ESMO25🇩🇪 🔥#LCSM Mini Oral, non-mets, SCLC ☑️DeLLphi-304: Safety analysis of phase III study to evaluate tarlatamab versus chemotherapy for previously treated SCLC ☑️All G AEs: Anemia 19.8%, Neutropenia 7.5% 🎙️ Dr. Martin H. Schuler @OncoAlert @myESMO @Larvol
1
11
21
@Tony_Calles
Dr. Antonio Calles 🫁🚭
1 month
💥 anti-TIGIT fails again (I can’t remember how many times I have posted negative results of these agents) 🏙️ Tiragolumab + atezolizumab did not improve PFS versus durvalumab in unresectable stage III NSCLC after chemoradiation in SKYSCRAPER-03 trial. #LCSM #ESMO25
6
20
68
@StephenVLiu
Stephen V Liu, MD
1 month
Dr. @NReguart discusses tarlatamab in #SCLC at #ESMO25. Outlines rationale and very reassuring to see consistency from other efforts. Will use of T Cell engagers be the future for all eligible patients with SCLC? #ESMOAmbassadors
1
22
72
@HHorinouchi
Hidehito HORINOUCHI
1 month
🔥 #ESMO25 🇩🇪 🔥 #LCSM Proffered paper, mets ☑️SOHO-01: Sevabertinib (BAY 2927088) in advanced HER2-mutant non-small cell lung cancer ☑️mPFS (PreTx w/o HER2, Pre HER2-ADC, Tx-naive): 8.3m, 5.5m, and not reached 🎙️ @LeXiuning @OncoAlert @myESMO @Larvol
@HHorinouchi
Hidehito HORINOUCHI
2 months
🆙#ESMO25 PREVIEW🇩🇪 🔥#LCSM Proffered paper, mets ✅SOHO-01: Sevabertinib (BAY 2927088) 🎙️ @LeXiuning @OncoAlert @myESMO @Larvol
0
14
23
@DrRiyazShah
Dr Riyaz Shah
1 month
BEAMION-Lung01; 1st line dataset from cohort 2; zongo 120mg od; stable and or asymptomatic bm; n=74; 66% YVMA; ORR 77%; DCR 96%; responses early; no new toxicity signals; 3% ILD (mild) #ESMO25
1
3
5
@HHorinouchi
Hidehito HORINOUCHI
1 month
🔥 #ESMO25 🇩🇪 🔥 #LCSM Proffered paper, mets ☑️Beamion LUNG 1: Zongertinib as first-line treatment in patients with advanced HER2-mutant NSCLC ☑️ORR 77%, 6m DoR 80%, 6m PFS 79% 🎙️ @DrSanjayPopat @OncoAlert @myESMO @Larvol
@HHorinouchi
Hidehito HORINOUCHI
2 months
🆙#ESMO25 PREVIEW🇩🇪 🔥#LCSM Proffered paper, mets ✅Beamion LUNG 1: Zongertinib 🎙️ @DrSanjayPopat @OncoAlert @myESMO @Larvol
0
12
33
@JordiRemon
Jordi Remon
1 month
ALEX trial 1st L alectinib (vs crizo) not ⬆️OS but trial not powered for OS. The best drug first? living w/o disease PD and good control of risk of brain PD count most!!Today lorlatinib is one SoC, futute SoC in 1st line Neladalkib (NVL655), ALKZAR trial vs alectinib?. #ESMO25
0
22
49
@DipeshUpretyMD
Dipesh Uprety MD FACP
1 month
PACIFIC-2 @JCO_ASCO ➡️Pts with unresectable stage III NSCLC randomized (2:1) to durvalumab or placebo from the start of concurrent chemo-RT ➡️No difference in PFS and OS #LCSM @OncoAlert @BTFCancerNews https://t.co/7PzFLbgGBp
Tweet card summary image
ascopubs.org
PURPOSEImmunotherapy targeting PD-L1 improves outcomes in patients with unresectable stage III non–small cell lung cancer (NSCLC) and no progression after definitive, concurrent chemoradiotherapy...
0
0
3
@chadinabhan
chadi nabhan MD, MBA, FACP
1 month
It’s happening @myESMO #ESMO25
0
2
6
@JordiRemon
Jordi Remon
1 month
HER2 TKI for HER2m NSCLC are real again Zongeritinib (the 2nd xombie 🧟‍♂️) outstanding activity in 1st Line (n=74, 30% Brain mets) with most G1-2 AEs (better safety than sebavertinib) Ready to replace 1st line CTIO? Awaiting for the ph3 trial BeamionLung02 zonge vs SoC #ESMO25
0
12
35
@DipeshUpretyMD
Dipesh Uprety MD FACP
1 month
FLAURA-2 @NEJM ➡️Pts w/ advanced NSCLC randomized to osimertinib versus chemo plus Osi ➡️↑ OS with chemo plus osi (Md OS: 47.5 mo vs. 37.6 mo; HR: 0.77) @OncoAlert @BTFCancerNews #LCSM https://t.co/IDiTEh1aBL
nejm.org
The primary analysis of this trial showed that first-line treatment with osimertinib plus chemotherapy with a platinum-based agent and pemetrexed led to significantly longer progression-free surviv...
0
0
0
@RManochakian
Rami Manochakian MD, FASCO Cancer Education
1 month
🚨🔥@OncoAlert Hot Off The Press Just published @NEJM #OverallSurvival data from: ⭐️#FLAURA2 trial of #Osimertinib + #Chemotherapy vs #Osimertinib in 1st line Tx for patients with #EGFR+ advanced #LungCancer (#NSCLC). ✅Impressive Statistically Significant & Clinically
2
27
67