dhuv.io
@DhuviKarthikey1
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Microbio x Data Sci @UCBerkeley | Comp Bio @CompMedUNC and Biophysics @UNC_BCBP 👨🏫. Building the foundations of Immunological Self-Determination. ☣️🧬👨💻
PIRL HQ
Joined January 2020
As de novo pMHC binders become commodity, the role of the wild type TCR starts to evolve. Both have their place, but lately it feels like all progress was in binders. No longer. Pleased to report that the first AI-TCR against a non-viral epitope has been achieved TCR-TRANSLATE🧵
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I’m having increasingly visceral reactions to ChatGPTisms, but this style takes the cake: “X is not just Y but also Z” “It’s not just X, it’s Y.” “It’s more than just X, it’s Y” Its everywhere plz make it stop ——— @iamgingertrash was right: ppl are developing anti-slop immunity
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1M citations! 🤯 Congratulations, @Yoshua_Bengio! Such an honor to have learned so much from you.
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Cambridge, MA is a special place Hangouts are spent discussing clinical trial designs, banking regulations, morality, domain specific AI benchmarking etc Everyday I’m learning so much by just being immersed amongst the coolest ppl
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Its not even been a month since @thinkymachines released Tinker & Stanford already has an assignment on it
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@jura_bio Bottleneck 3: No matter your level of automation, running experiments that measure what matters often face real-life limits. We built LEAVS https://t.co/vRiIisnB3t to extract ~100x more information from each data point. (Preprint live tomorrow on Arxiv!)
jura.bio
A fundamental lesson of modern AI is that scale is essential: training bigger models on bigger datasets unlocks new capabilities. A fundamental lesson of AI engineering is that scaling up isn't...
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"I can’t help you implement or optimize generation of biological sequences. That would be assistance for designing biological sequences, which I’m not able to provide." -Your favorite LLM's favorite LLM, October 2025
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BREAKING: Robbery of jewelry that had once belonged to Napoleon and his empress triggered closure of Louvre museum today
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Let’s say we are in fact the average of the five people we spend the most time with. What does it mean for us when an LLM becomes one of those five? What does it mean for one of the five to be a sycophant with access to all of the Internet? Much to consider
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C2S, powered by Gemma, is enabling us to generate and test new biological hypotheses — an amazing collaboration with @GoogleAI and @GoogleDeepMind!
⚕️ Introducing C2S-Scale 27B, our new Gemma open model that can translate complex single-cell gene expression data into “cell sentences” that LLMs can understand.
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Does anyone know of a semi free service where I can upload a song and a modified set of lyrics and some model reads my lyrics to the tune of the original? Will upload here after
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me: i just spent all day scrolling my friend: it happens 12th century chinese scholar: hell yeah
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This October I’m drawing 1 molecule a day inspired by proteins in pdb @buildmodels #Inktober2025 Day 11 Prompt STING Pdb: 6MZT Scorpion venom protein Urotoxin. Next:SHREDDED Suggestions?
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The final frontiers of human biology will be immunology and neurology
It’s all the immune system, wide reaching tendrils of the lymph
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Introducing Exacto: long-read somatic & germline DNA and RNA variant caller, DNA+RNA variant integrator, and mutant peptide sequence predictor for neoantigen discovery. It builds on the Occam's Variant Grammar that I previously proposed. https://t.co/6rNDrWnLyT
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"Do your best while you're still on this beautiful planet Earth."
Dr. Jane Goodall filmed an interview in March 2025 with the understanding it would only be released after her death. This is her final message from it.
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#Treg it is.Congratulations
Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi have been awarded the 2025 Nobel Prize in Physiology or Medicine for their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body. The Nobel Prize laureates
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Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi have been awarded the 2025 Nobel Prize in Physiology or Medicine for their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body. The Nobel Prize laureates
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Didn’t expect to log on to see Chapel Hill getting glazed but I’ll take it 😭
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China is shaping up to be everything I was expecting Dubai to be when I was growing up.
Chongqing East Railway Station — now the world’s largest high-speed rail terminal. With 15 platforms, 29 tracks, and covering 1.22 million m² (≈ 170 football fields), it’s a mega mobility hub. https://t.co/ThLJb1fffP
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