PET Connectivity
@ConnectivityPet
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Official page of the Molecular Connectivity Working Group (MCWG).
Joined June 2021
@OHBM 2025 is around the corner! Check out the two symposia by the Molecular Connectivity Working Groups.
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🔹Two distinct pathological clusters emerged: hypo‑connected default mode and hyper‑connected limbic.🔹Hyper-connectivity in limbic regions predicts faster metabolic decline and quicker progression to dementia.
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Key Findings:.🔹Early AD shows both hypo‑ and hyper‑connectivity in different brain networks.
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🧠New Study Spotlight.📝Glucose metabolism in hyper-connected regions predicts neurodegeneration and speed of conversion in Alzheimer’s disease.Longitudinal analysis of brain metabolic connectivity on neurodegeneration in Alzheimer’s disease. Full study:
link.springer.com
European Journal of Nuclear Medicine and Molecular Imaging - Here, we combined a longitudinal design to assess whole-brain hyper- and hypo-connectivity in the different clinical phases of...
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#Throwback to Brain & Brain PET last month in Seoul, S. Korea!. Including a keynote presentation about Current Advances in Molecular Connectivity with @tommaso_volpi, @SharnaJamadar, @Herfert_lab and M. Reed
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Thanks, again for everyone that contributed to the two MCWG symposia at the recent @OHBM . I.) Bin Wan, A. Bertoldo, J. Chen and @DeeryHamish, @dixy0, @SharnaJamadar .II.) @dtalmasov, A. Jasanoff, M. Burkhardt, Z. Liu, and @MatejPerovnik, @Felix_BnB, @jchrispang.
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Check out the oral presentation by Mengyuan Liu about Unveiling the biological substrates of glucose metabolic covariance in the human brain @OHBM 2025!. Today, June 28 at 11:42 in the Great Hall!.
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Today is the day! Don't miss the Keynote talk by @SharnaJamadar at OHBM 2025!.
⭐ Speaker Spotlight: Sharna Jamadar.🗓️ June 28 | 🕥 10:30 – 11:15.Excited to feature Sharna Jamadar at OHBM 2025. More information about Sharna in the comments. #OHBM2025
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Come back to the @OHBM after lunch to listen to today's second MCWG symposium, now about Validating brain connectivity measures with @dtalmasov, A. Jasanoff, M. Burkhardt, Z. Liu, and @MatejPerovnik moderated by @Felix_BnB and @jchrispang. We start at 15:45 in the Great Hall!
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Good morning @OHBM! Don't miss today's Molecular Connectivity Working Group symposium about the relationship between Brain Energy Consumption and Brain Organizations with Bin Wan, A. Bertoldo, J. Chen and @DeeryHamish, moderated by @dixy0. We start at 9:00 in the M3.
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The recording of the talk is now available on our YouTube channel:
At the next #MCOS, we are excited to welcome Dr. Simon Eickhoff (@INM7_ISN), who will be presenting:. "Great expectations but bumpy road: Caveats in neuroimaging analyses and modeling.". We start at: Fri, May 23, at 9am ET, 3pm CET. Register here:
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The recording of the talk is now available on our YouTube channel:
Next #MCOS is just around the corner! Come for the talk, stay for the discussion! 🗣️🗣️. We will look at Molecular Connectivity in Neurotransmission. Presented by M. Veronese and M. Severino. We start at: 9am EDT, 3pm CET, 10pm CST .Register here:
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Read more about molecular studies in neurotransmission in a paper from the MCWG!.
New paper in Imaging Neuroscience by Mario Severino, Mattia Veronese, et al:. Molecular connectivity studies in neurotransmission: a scoping review.
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Join us tomorrow!.
Next #MCOS is just around the corner! Come for the talk, stay for the discussion! 🗣️🗣️. We will look at Molecular Connectivity in Neurotransmission. Presented by M. Veronese and M. Severino. We start at: 9am EDT, 3pm CET, 10pm CST .Register here:
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Ps. If you would like your work to be shared on our channel, don't hesitate to write!.
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Check out the study by Khokar et al. in which they explore metabolic network distruptions in FTD subtypes.
Thrilled to share latest publication in Network Neuroscience. @netneurosci @mitpress.We used a multiplex connectomics approach (Cortical thickness & FDG-PET) to reveal distinct network disruptions in FTD subtypes (bvFTD & PPA).
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Next #MCOS is just around the corner! Come for the talk, stay for the discussion! 🗣️🗣️. We will look at Molecular Connectivity in Neurotransmission. Presented by M. Veronese and M. Severino. We start at: 9am EDT, 3pm CET, 10pm CST .Register here:
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Congratulations to the authors: A. Verger, M. Doyen, S. Heyer, F. Goehringer, A. Bruyere, E. Kaphan, M. Chine, A. Menard, T. Horowitz & E. Guedj.
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Full study (open access!) available in EJNMMI Research.
ejnmmires.springeropen.com
Background A hypometabolic brain pattern has been reported in patients with post-COVID condition (PCC). The aim of this study was to investigate reorganization in metabolic connectivity in patients...
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📜🧠 Metabolic Connectivity (MC) alterations in Post-COVID Condition (PCC). Multicenter study on 188 PCC patients (18F-FDG):.↓ Connectivity efficiency.Altered MC, stronger >9M post-infection. 📌 PCC leads to lasting MC reorganization, suggesting functional adaptation over time.
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