Lan Coffman lab
@CoffmanLab
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improving lives of women with ovarian cancer through research @upmchillmancc a focus on the stromal tumor microenvironment
Joined June 2020
Check out our newest publication showing endometriosis-derived stroma drive ovarian clear cell cancer through iron regulation!.
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RT @JCI_insight: #ClinicalMedicine: Safety demonstrated for CDK4/6 inhibitor with chemotherapy in ovarian cancer: .
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We are hiring! Explore our Translational Ovarian Cancer Post-doctoral Fellow position:
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RT @BuckanovichLab: Super excited about a new study we published today. This work shows CA-MSC are driving tumor immune exclusion and resis….
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this reprogramming is reversible and associated with patient survival and may be a new therapeutic target in ovarian cancer.
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we found ovarian cancer induces a mesenchymal to epithelial transition in stromal cells allowing stromal cells to bind and co-metastasize with cancer cells.
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excited to share our new work published today in Cell Reports.
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Epigenomic Reprogramming toward Mesenchymal-Epithelial Transition in Ovarian-Cancer-Associated Mesenchymal Stem Cells Drives Metastasis: Cell Reports
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