Kei Cho Lab
@ChoLab_Synapse
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Synapse & Therapeutic Discovery Lab in the Department of Basic and Clinical Neuroscience, @KingsIoPPN @KingsCollegeLon @UKDRI #Neuroscience #AlzheimersDisease
London, UK
Joined August 2023
#AI prediction was right-Location Location Location of Synapse. "Micro-sub regional synapse weakening by mimicking the hyperphosphorylation of Tau" Our recent #Tau story. @UKDRI @KingsIoPPN @KingsCollegeLon @adpdnet See more here;
academic.oup.com
Mitchell et al. report that phosphorylation-mimic Tau (TauPHF1E) selectively weakens synapses in distal CA1 dendrites, impairing PSD-95 expression, dynamic
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RT @braincomms: Mitchell et al. report that phosphorylation-mimic Tau selectively weakens synapses in distal CA1 dendrites, impairing PSD-β¦.
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Very Hot (topic & weather) @JNJInnovation Life Sciences Innovation Event in London. Catch up with old friends, ex-students and new friends. Amazing R&D budget well over 17 billion USD. Brilliant talk presented by Nerida Scott. π @KingsIoPPN @UKDRI @adpdnet
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Dr Sarah Marzi gave an exciting presentation at #BioKorea2025, "Using epigenetics to understand how different brain cells malfunction in Importance of Epigenetics #AlzheimersDisease. @KingsIoPPN @UKDRI @KingsCollegeLon @adpdnet
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Just kicked-off #BioKorea2025. Plenary Lecture by Alex Zhavoronkov, talk about #AI #DrugDiscovery #Aging #Therapeutics. Very exciting concept for "Dual-purpose" therapeutics, could be used for Brain aging and neurological disorders. π
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Absolutely Great #ADPD2025, hope to attend and hear more exciting talks next year. Many congratulations π₯³ and big tanks, specifically PhD students, Postdocs and Exhibition for their hard work. Well done all. @UKDRI @KingsCollegeLon @adpdnet.
Thank you for an amazing #ADPD2025 β 5 days filled with the latest insights and advancements in science and therapy! π€© . We hope to welcome you again at the next edition of AD/PDβ’ on March 17-21, 2026 in Copenhagen, Denmark. Follow us on social media and stay tuned for more
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Even last day #ADPD2025, EXCELLENT poster Eve Wong from @KlenermanLab @UKDRI @Cambridge_Uni π€© Wow, amazing tool, π great job. Hope to reveal more about #Tau aggregation and understand specific mechanisms of pathophysiology. Great conference! @adpdnet
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What a wonderful talk!! Dorothea Boeken (@KlenermanLab) @Cambridge_Uni, advanced single molecule-super resolution Tau image assay. UNVEILING THE MOLECULAR LANDSCAPE OF TAU AGGREGATES IN ALZHEIMERβS DISEASE AND OTHER TAUOPATHIES. @UKDRI #ADPD2025 @adpdnet π
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Very exciting presentation by Prof Spires-Jones (PRE-COMPETITIVE ANALYTICAL VALIDATION OF SV2A PET AS A BIOMARKER OF SYNAPTIC DENSITY), @UKDRI @EdinburghUni at AD/PD2025 Vienna #ADPD2025
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CogNanoπ―π΅ introduced #AI based #DrugDiscivery with a large-scale VHH (nanobody) dataset for #Oncology #Alzheimers (Abeta/Tau) and beyond. Smart epitomics using bar-coded structure probe. π€© @KingsCollegeLon @UKDRI @UKinJapan @biztradegovuk @lifearc1
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Day 1 Forum group photos with George Freeman @MPGeorgeFreeman and speakers/guests fromπ¬π§ @UniofOxford @Cambridge_Uni @DHSCgovuk @SciTechgovuk @The_MRC @UKDRI @AMED_officialGL JETRO-Londoπ―π΅ MOHWπ°π· organised by @KingsCollegeLon #LifeScience #HealthTech #AI
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Day2 Life Science, Digital &Health Innovation Forum. Opening by Ms Patel @biztradegovukπ¬π§ Ms E-K Jung (MOHWπ°π·) Mr M Sakishige (JETRO London π―π΅) Exciting presentation/discussion from @lifearc1 @globalbrains_jp @AstellasEurope organised by @KingsCollegeLon
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Great start Day1 Life Science, Digital & Health Open Innovation Forum. π¬π§ π―π΅ π°π· together. Opening by George Freeman @MPGeorgeFreeman, exciting Science from Prof Sir Klenerman @Cambridge_Uni & Prof. Ule @KingsIoPPN @UKDRI we discussed #LifeScience and #AI.
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Pleased to announce LifeScience, Digital & Health Open Innovation Forum (Solutions to Improve the Quality of Life) in London, 3-4March 2025, supported by @The_MRC @KingsCollegeLon @KingsIoPPN @SciTechgovuk @DHSCgovuk @biztradegovuk @UKDRI @RosFrankInst
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Great memories from the 6th Japan-UK #Neuroscience Symposium. What a wonderful event at #Awaji π―π΅ Thank you so much for all. See you in π¬π§ π @KingsIoPPN @KingsCollegeLon @UKDRI @cardiffuni @NagoyaUniv @juntendo_univ @osaka_univ_e @The_MRC @AMED_officialJP
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The 6th Japan-UK Neuroscience Symposium is closed, two poster prizes; π―π΅ Diane Pagano @Hayashi Lab @KyotoU_News π¬π§ Madeleine Gilbert @Frank Lab @UniversityLeeds Many congratulations, two PhD student's brilliant data π and hard work. @The_MRC @AMED_officialJP
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Our Team-4 won the 2nd place π prize (γγγΌγΉγΏγΌγ©γΌγ‘γ³γNori snacks)!! π.
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Prof Kenji Doya @OISTedu give a plenary lecture about #computational neuroscience, reward robotics model, digital brain at the 6th Japan-UK Neuroscience Symposium. Very interesting π π @The_MRC π¬π§ @AMED_officialJP π―π΅
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Prof Maria Spillantini @Cambridge_Uni gave a historic plenary lecture about Tau-Synuclein at the 6th Japan-UK Neuroscience, Awaji-Japan. Also recent update; gut related pathology in PD. @The_MRC @AMED_officialJP π
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