Zhe (Sage) Chen
@Chen3Sage
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computational neuroscientist, Argentine tango dancer, world traveler. I am designing closed-loop brain-machine interface for modulating animal's acute pain.
Manhattan, NY
Joined August 2016
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Closed-loop stimulation using a multiregion brain-machine interface has analgesic effects in rodents
science.org
A multiregion brain-machine interface automatically detects pain and delivers ultrafast analgesia for acute and chronic pain in rodents.
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New research results: Excitatory-Inhibitory Recurrent Dynamics Produce Robust Visual Grids and Stable Attractors
biorxiv.org
Spatially modulated grid cells has been recently found in the rat secondary visual cortex (V2) during activation navigation. However, the computational mechanism and functional significance of V2...
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Great project with Dr. Geng and @Chen3Sage! Looking forward to many more productive collaborations between @nyulangone, @UMneurosurgery, & @UMiamiNeuro. Deep learning for robust detection of interictal epileptiform discharges https://t.co/ZQr6idbMJK via @IOPscience @AAlkhachroum
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New Neuron paper on "Improving scalability in systems neuroscience" is out:
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Egocentric Asymmetric Coding in Sensory Cortical Border Cells
biorxiv.org
Both egocentric and allocentric representations of space are essential to spatial navigation. Although some studies of egocentric coding have been conducted within and around the hippocampal format...
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Egocentric Asymmetric Coding in Sensory Cortical Border Cells https://t.co/2DCmEEvrBO border cells are shows direction specific tuning! in both rat S1 and V2!
biorxiv.org
Both egocentric and allocentric representations of space are essential to spatial navigation. Although some studies of egocentric coding have been conducted within and around the hippocampal format...
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A fresh new take on decoding: using >300Hz signal peaks instead of sorted spikes
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The Cooper Square Review: A new way to treat mental illness
coopersquarereview.org
Scientists are discovering new ways to treat mental illness -- with mind-reading tech straight out of The Matrix.
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speed matters in closed-loop neuroscience....new paper on real time readout on memory replay @CellReports
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speed is the everything !
This #InnovativeMethodology article describes a new approach to sequential change-point detection. Read: "Real-time particle filtering and smoothing algorithms for detecting abrupt changes in neural ensemble spike activity." Link: https://t.co/h7IsBNk9cI
#spiking #stochastic
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Uncovering representations of sleep-associated hippocampal ensemble spike activity
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