Changya
@Changya1
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Joined August 2014
RT @KaiTanLab1: Excited to share the first spatially resolved multiomics atlas for human bone marrow, published today in @CellCellPress. ht….
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RT @ZevGartner: Excited to announce deMULTIplex2 - a powerful new classification algorithm for multiplexed scRNA-seq data from the Gartner….
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RT @KaiTanLab1: Great presentation @ASH_hematology by another lab member, Changya Chen @Changya1 on characterization of progenitor-like bla….
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Thanks for your nice review!.
Check out our review of the single-cell multiomics work done by @KaiTanLab1 on KMT2Ar leukemia. It's great to see progress on improving outcomes in pediatric cancers! @vangalenlab @cdktmw @Changya1 @wbaopaul.
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RT @KaiTanLab1: Happy to share our newest study on KMT2Ar leukemia using single cell multiomics! ..
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RT @CD_AACR: Just published #OnlineFirst: Integrative bulk and #singlecell profiling of pre-manufacture T-cell populations reveals factors….
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So excited to share our preprint about infant leukemia study at single-cell resolution!.
Excited to share our single-cell multi-omics study of a high-risk subtype of leukemia, as part of the @NCIHTAN. Tremendous effort by multiple labs at @CHOPCancerCntr, @penngenetics, @pennpathlabmed, @childrensmercy, @HopkinsKids. @bioRxiv viewer
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RT @KaiTanLab1: Diverse noncoding mutations contribute to deregulation of cis-regulatory landscape in pediatric cancers .
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RT @cdktmw: Excited to share our new method MAPLE for integrating single-cell methylome and transcriptome data based on supervised learning….
biorxiv.org
Despite rapid advances in single-cell DNA methylation profiling methods, computational tools for data analysis are lagging far behind. A number of tasks, including cell type calling and integration...
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RT @KaiTanLab1: Very proud of our study. Technically very challenging experiments to do, dealing with rare primary hematopoietic stem cells….
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RT @cdktmw: Very excited to share the joint work with the Speck lab to map the transcriptional regulatory circuitry during definitive embry….
biorxiv.org
Hematopoietic stem cell (HSC) ontogeny is accompanied by dynamic changes in gene regulatory networks. We performed RNA-Seq and histone mark ChIP-Seq to define the transcriptomes and epigenomes of...
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Transcriptional regulatory network controlling the ontogeny of hematopoietic stem cells
biorxiv.org
Hematopoietic stem cell (HSC) ontogeny is accompanied by dynamic changes in gene regulatory networks. We performed RNA-Seq and histone mark ChIP-Seq to define the transcriptomes and epigenomes of...
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scATAC-pro: a comprehensive workbench for single-cell chromatin accessibility sequencing data
biorxiv.org
Single cell chromatin accessibility sequencing (scCAS) has become a powerful technology for understanding epigenetic heterogeneity of complex tissues. The development of several experimental protoc...
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scATAC-pro: a comprehensive workbench for single-cell chromatin accessibility sequencing data
biorxiv.org
Single cell chromatin accessibility sequencing (scCAS) has become a powerful technology for understanding epigenetic heterogeneity of complex tissues. A number of experimental protocols have been...
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