Ajith Karunarathne, PhD (he/him)
@Cellphotochem
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Biochemist, molecular cell biologist, associate professor @SLUChemDept, editorial board member @PLOSOne and @jbiolchem, PI in Molecular Cell Lab @SLUChemDept
Saint Louis
Joined November 2017
RT @glycoworld: Come and join us at SLU Department of Chemistry. We seeks applicants for a tenure track assistant professorship in the fiel….
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RT @jenheemstra: Research inherently comes with uncertainty. The key is to focus on what we can control. Not every idea will work right aw….
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RT @biorxivpreprint: Spatiotemporal optical control of Gαq-PLCβ interactions #bioRxiv.
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Happy to share our latest work now spatiotemporal optogenetic control of Galphaq signaling. You can access the preprint version in biorxiv now.
biorxiv.org
Cells experience time-varying and spatially heterogeneous chemokine signals in vivo, activating cell surface proteins, including G protein-coupled receptors (GPCRs). The Gαq pathway activation by...
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RT @biorxivpreprint: CaaX-motif adjacent residues control G protein prenylation under suboptimal conditions #bioRx….
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Happy to announce our latest research live on biorxiv as a preprint!.
CaaX-motif adjacent residues control G protein prenylation under suboptimal conditions #bioRxiv.
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RT @YoungGroupChem: at these systems, recently culminating in our ability to "turn off" the C–H activation by exploiting the rate determini….
pubs.rsc.org
Cinnamylamines make-up many important drugs that target G protein-coupled receptors. While 3,3-diarylallylamines can be prepared via existing synthetic methods, these often require poorly-selective...
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RT @YoungGroupChem: products. The reason for this is that in situ-formed nanoparticles were found to give the Mizoroki–Heck coupling produc….
pubs.acs.org
Palladium-catalyzed organometallic transformations of free amines are often unsuccessful due to side reactions, such as oxidation, that can occur. However, the ability to furnish the free amine...
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RT @YoungGroupChem: Happy to share our recent preprint: Having worked on the Pd-catalyzed functionalization of all….
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Our latest article was just published in Nature Scientific Reports! Congratulations to my current and former team members for unveiling crucial signaling mechanisms published here underlying GPCR physiology and pathology!.
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Happy to share the preprint version of our latest article on Molecular regulation of GPCR-G-protein-governed PIP3 generation and its adaptation
biorxiv.org
Phosphatidylinositol (3,4,5) trisphosphate (PIP3) is a plasma membrane-bound signaling phospholipid involved in many cellular signaling pathways that control crucial cellular processes and behaviors,...
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I am excited to congratulate the latest Ph.D. recipient from my @cellphotochem at the @UToledo, Dr. Mithila Tennakoon! She defended her dissertation titled "Molecular regulation of G protein localization and its pharmacological implications" exceptionally well. @chemistrytoledo
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RT @UToledo_NSM: Shout out to Mithila Tennakoon, @UToledo Ph.D. student @Cellphotochem @ChemistryToledo who received a third-place award at….
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Postdoctoral position in protein engineering & optogenetics @ Ajith-Lab at @UToledo, USA. Send cover letter, CV, & a list of three references in one pdf to Also, email it ajith.karunarathne@utoledo.edu. Review start: 8/30/21. @chemjobs2, @PostdocJobs.
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Postdoctoral position in protein engineering & optogenetics @ Ajith-Lab at @UToledo, USA. Send cover letter, CV, & a list of three references in one pdf to Also, email it ajith.karunarathne@utoledo.edu. Review start: 8/30/21. @UToledo_NSM @ChemistryToledo.
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Postdoctoral position in protein engineering & optogenetics @ Ajith-Lab at University of Toledo, USA. Submit cover letter, curriculum vitae, & a list of three references in one pdf to Also, email it ajith.karunarathne@utoledo.edu. Review start: 8-30-2021.
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