Gabriel Cavin-Meza
@Cavinameltdown
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Postdoc in the Heald Lab at UC Berkeley; interested in how microtubule spindles adapt to changing cellular contexts
Berkeley, CA
Joined September 2019
Excited to share my latest work with @adernburg
https://t.co/a87yvrhKyW where we uncover a new Piezo-dependent checkpoint mechanism monitoring oocyte quality at the nuclear envelope (NE), using an in vivo chemically induced proximity (CIP) tool we developed. 1/7
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Our paper is out! Xenopus embryos follow #kleiber’s power law between metabolic rate and body mass. But triploids embryos which are made of fewer larger cells have a lower metabolic rate than diploids. 1/3
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It's finally published! Who thought you could use laser tweezers in a frog egg extract! A fun collaboration with the Bustamante lab at Berkeley
pnas.org
DNA compaction is required for the condensation and resolution of chromosomes during mitosis, but the relative contribution of individual chromatin...
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The MAYosis 2023 website is open! 5 sessions will feature 5 speakers; 1 keynote and 4 talks selected from abstracts. Only trainees & junior faculty (<6 years of starting their lab) will be considered for a talk. Abstracts due March 1. Apply now! https://t.co/FjBoHqKBxI
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Excited to share a preprint! We make barrel-shaped, pole-less spindles and ask which properties emerge locally from k-fibers and which emerge more globally from focused spindle poles. Congrats Manuela Richter @mannylikescells and all authors!!!
biorxiv.org
At each cell division, nanometer-scale components self-organize to build a micron-scale spindle. In mammalian spindles, microtubule bundles called kinetochore-fibers attach to chromosomes and focus...
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The last project I worked on in the Wignall Lab (@monospolarpindl) is finalized and is fully online! It was a blast to be a part of a collaborative paper started by @tjmullen33 and excited to see where future research of ZYG-9(XMAP215) leads! https://t.co/H3CARk0hI1
journals.plos.org
Author summary The spindle is a dynamic microtubule-based structure that functions to segregate duplicated chromosomes during cell division. In many types of cells, protein-rich structures known as...
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Excited to share our work out in @eLife using modeling and experiments to probe the underpinnings of the mammalian spindle's heterogeneous mechanics. In collaboration with Rob Phillips' lab. Congrats @poojasuresh47 and @galstyan_vahe!
elifesciences.org
Coarse-grained modeling of mammalian kinetochore-fiber shapes generated under microneedle manipulation reveals the need for lateral anchorage 1-3 μm from the kinetochore to robustly preserve their...
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Our lab @UCSF is currently recruiting a postdoc! We work on the self-organization and mechanics underlying cell division, somewhere between cell biology & biophysics. Come join us! We will all be at ASCB if you want to chat there. Please RT.
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A wonderful lab and great advisor - would strongly recommend to anyone!
My lab at Northwestern is hiring a technician! The job involves both lab management and independent research. No specific experience is required – we are searching for someone motivated to learn! Previous techs went on to top grad schools. Great location near Chicago. Please RT!
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Our newest paper is out @eLife! Check it out to learn about how motors form and stabilize acentrosomal spindles. Congrats to first author @Cavinameltdown for spearheading this important work! @monospolarspindl
elifesciences.org
Rapid depletion of dynein from oocytes yielded new insights into acentrosomal pole organization and also led to the first evidence that the kinesin-5 motor BMK-1 plays a role in microtubule organiz...
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Check out the new preprint from my lab! Highly collaborative project with beautiful work from @tjmullen33 and @Cavinameltdown (co-first authors), and @IDWolff @EmilyCzajkowski Nikita Divekar, and @j_d_finkle.
biorxiv.org
During mitosis, centrosomes serve as microtubule organizing centers that guide the formation of a bipolar spindle. However, oocytes of many species lack centrosomes; how meiotic spindles establish...
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I'm pleased to share my first preprint in the Wignall Lab with the meiosis community, and I hope others find it as exciting to read as I do! Very appreciative of reviewer comments to help improve the paper, and excited to get this work published soon! https://t.co/tXOESyvYDp
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10/10, would marry a third time. Here’s to a wonderful wife, wonderful wedding, and a wonderful future. #CavinAGoodTime #wedding Many thanks to our amazing photographer Manali ( https://t.co/OzXD5F9pAX)
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Week 3 of #MAYosis2021 is tomorrow, and its all about chromosome segregation! Come and hear Ahmed Balboula, @scienceLeah, @fpelisch, @BlenginiCecilia (from @KASchindler27's lab), and @Cavinameltdown (from @swignall's lab). Moths, mice, and worms, oh my!
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In this #CurrentProtocols article, Nikita S. Divekar @hannahhearsawho & @swignall outline multiple methods for inducing auxin‐mediated depletion of target proteins in C. elegans, highlighting the versatility and power of this method. https://t.co/RgoMvVpByu
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to make it here without dying is the epitome of white privilege
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Those who seek power over others are rarely the ones that should wield it.
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BREAKING: The Trump administration will rescind its order blocking foreign students from living in the U.S. while taking classes online. A federal judge in Massachusetts just announced that the government and plaintiffs reached a resolution, @JuliaEAinsley reports.
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