More evidence that the consumption of UPFs negatively impacts every organ in our body: now linked to female infertility in a representative sample of the American population (with previous studies in Spain and Italy showing links to male infertility).

From the outstanding Moli-sani cohort investigators: "High adherence to a traditional Mediterranean diet + low UPF intake improved survival and reduced non-cancer mortality. Guidelines should stress cutting UPFs to fully unlock the MD’s health benefits".

I wonder whether my peers in the U.S., affiliated with the American Society for Nutrition — in addition to Marion — are aware of this shameful situation.

I couldn’t agree more!!!.

UPFs are the ultimate expression of fossil-fueled food systems—born from commodity crops grown with fossil-fueled agrochemicals, harvested with fossil-fueled machinery, shaped by energy-intensive processing, wrapped in plastic, and shipped around the world.

Incredibly important—at least for the U.S., I think.

The American College of Lifestyle Medicine now recommends emphasizing Nova Group 1 (unprocessed or minimally processed foods) and minimizing/avoiding Nova Group 4 (UPFs) to prevent and manage type 2 diabetes—endorsed by 8 other U.S. medical associations.

Join the call to #KickBigSodaOut and promote health!.

After Brazil, Colombia, Senegal & India, Ecuador becomes the 5th country with a validated 2–3 min Nova24h screener—enabling Nova UPF score calculation, one of four WHO/FAO/UNICEF-recommended metrics to monitor healthy diets globally.

Want to know how Brazil uses the NOVA food classification & UPF concept? This paper breaks it down and shares Brazil recent trends in UPF consumption.

Great Lancet editorial on UPFs—except the claim that policies targeting all UPFs are unrealistic due to their vast number. Maybe true in UK/US, where UPFs dominate. But in most countries, real food still prevails—or UPFs are just starting to rise. Yet!.

UPF science is evolving. High-UPF diets show distinct blood & urine metabolomic profiles—matching known harms. Biomarkers may soon track UPF exposure & deepen our understanding of how UPFs cause disease. Yet policy action still lags.

Innovative UK adult cohort trajectory study found that a sustained high intake of UPF over a decade was associated with an increased risk of CVD and CHD over a 16-year follow-up period. Authors recommend UPF regulation and review of dietary guidelines.

New study (Am J Prev Med) in 8 countries estimated that 3.9% (Colombia) to 13.7% (USA) of all premature deaths (ages 30-69 y) are due to UPF consumption—more than 100,000 deaths annually in the United States alone.

Excellent review on how UPF consumption may impact neuropsychiatric health—exploring the underlying mechanisms.

A welcome AJCN editorial calls for more efforts to quantify and understand the most important risk factors for the rapidly increasing incidence of chronic conditions at younger ages, including exposure to UPFs and the compounds added to them.

A new study using risk estimates from a dose-response meta-analysis + national dietary data shows that 21% of obesity cases (277,056 out of 1,286,454) and 23% of type 2 diabetes cases (53,348 out of 227,502) in Belgium could be prevented by avoiding UPFs.

"Using successful strategies from public health campaigns to reduce youth tobacco use may be crucial in changing public attitudes and behaviors regarding UPF consumption.".

Another study links high UPF consumption to less favorable gut microbiota and metabolite profiles—pointing to reduced short-chain fatty acid production, disrupted mitochondrial energy metabolism, and impaired amino acid metabolism.

Big step toward UPF regulation in California. Prof. Gearhardt: “UPFs aren’t just unhealthy—they’re engineered for overconsumption. Like addictive substances, they hijack the brain’s reward system, making it hard to cut back—even with serious health risks"