Our colleagues will of course decide whether the new NK classification proposed by @EricVivier1 is useful. What their decision, I do think a classification that makes sense of both mouse and NK subsets would be very useful to the field.

Our contribution was to show that mouse NK cells develop by 2 pathways, and that the transcriptional signatures that defined these 2 mouse NK subsets also distinguished human NK subsets defined by CD56.

Glad to have contributed to the work by Rebuffet, @EricVivier1 and colleagues, reposted below.

Vivier and colleagues integrated scRNA-seq and CITE-seq data to provide a resource of human NK cell heterogeneity in healthy tissues and in the tumor setting. Read it here: https://t.co/fTaQp3LNxC https://t.co/yZrLSXRhhl

And here are the links to the two new papers in Nature Immunology. From us and our collaborators @SimonGrassmann, @SunLab_Official, @BelkaidLab https://t.co/ZaxtS0G5Sa From the lab of Bendelac and McDonald: https://t.co/ZYbuf9mfrJ

And here is the thoughtful N&V from Emma Patey & @bjorkstrom_lab https://t.co/GCseoLjcc4

Such a bittersweet surprise to be back to back in Nature Immunology with Albert. To my thinking, our two papers are very complementary.

The original papers are here, one from our lab, one from the lab of Albert Bendelac. https://t.co/WWLyIlhDsC https://t.co/6nFFQXtOha

Great summary from Emma Patey & @bjorkstrom_lab about the 2 recent papers studying NK cell developmental origins from the late Bendelac's lab & the Bhandoola's lab: https://t.co/GvLLvBDMrm ILCs with more nuance! Orginal studies: https://t.co/MFfl2XBFlG https://t.co/DBA6g0l0RJ

Bhandoola and colleagues describe the existence of two developmental pathways that give rise to functionally distinct NK cell subsets. Read it here: https://t.co/seVYU7nx0t https://t.co/HHZOT9yRMF

The CCR media team has a succinct outline of this latest work from our lab: https://t.co/pp6CPWHjdt

Online now: Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut

https://t.co/rruCpomL41 Other recent work from our lab. Stay tuned for more.

And here's the link to the paper itself, below. https://t.co/aIehlInOeC

Bone marrow plasma cells require P2RX4 to sense extracellular ATP https://t.co/mZIT0bi4fB The link is to a web-readable version of our lab's first paper on plasma cells. From a very fun collaboration between our lab at the National Cancer Institute and David Allman's lab at Penn.