Sarah Beattie
@BeattieLab
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University of Iowa @UIowaPeds. We use high throughput drug screening for the discovery and preclinical development of mold-active antifungals.
Iowa City, IA
Joined June 2022
It’s a great time of year to ask yourself “when was the last time the incubator intake vent was cleaned?” (if you have to ask then it’s time to clean it).
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Happy internal grant submission day to all who are celebrating!.
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This has been a really fun side project that has taught us a lot about an interesting family of plants!! Hopefully this little guy will be catching flies soon!.
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Today we took the plantlet and put it in moss to allow it to root.
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Submerged them in sterile, distilled water and waited for weeks. At first nothing happened but then a bump started to form and a baby plant emerged! Shown here is a plantlet growing from the center of the leaf.
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Experimenting with a different kind of cloning in the lab. plants!! We attempted to propagate a cape sundew through cuttings. First, we cut leaves off this mother plant (shown here flowering).
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RT @davidrandes: Congratulations to newly minted MBL #MOMY2024 alumni. Great things to come from this group. #MolecularMycology @cramer_la….
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Thoroughly enjoyed returning to Woods Hole to present my work at the Molecular Mycology course!
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PS. Although the ad describes an anti-fungal development project, this is still the correct link to apply!! Cell culture and animal handling experience preferred but not required.
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I am hiring a research assistant to work on elucidating mechanisms of cerebral pathogenesis using murine and cell culture models. If you're interested, apply here before aug 16th: Please share this link if you know of people who may be interested!.
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In a monumental effort, my research assistant completed a primary screen of 150,000 compounds!! There’s still a LOT of work to be done but in an academic setting with limited automation, this is quite the feat!!!.
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There is still a lot of work to do on this compound (and the many others we have identified in our screen which is up to ~1000K now!!) but we are excited to have some potential candidates to work with moving forward!.
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I almost forgot to post our most recent paper published in mSpectrum! We completed a screen of ~50K compounds and characterized one of our tops hits, a pyrimidine-based compound, which disrupts ER function in A. fumigatus! .
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It has been a whirlwind of a month but the Beattie lab has officially moved (across the hall)!! We are excited to grow into our new space and even more excited that the move is over now.
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After months of waiting with score one point over interim pay lines, I finally have a fundable score on my R21!!!!.
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RT @AmeliaBarberPhD: Why shouldn't we rely on a limited number of reference strains to study fungal pathogens? My thoughts in this month's….
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RT @NC_Renic: Don't forgot, editing is part of writing. Reading is part of writing. Lying facedown on the floor, worrying those around you,….
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Returning to the office after a snow day to emails I sent to myself from home with ideas to follow up on. is this PI life?.
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