
BCIS-4 Trial
@BCIS4Trial
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CABG or PCI in Patients with Ischaemic Left Ventricular Dysfunction (STICH3-BCIS4) led by @gavinjamesmurph and @divaka_perera coordinated by @leicesterCTU
Joined January 2024
Welcome to the @BCIS4trial X page. This study is funded by the National Institute of Health Research (NIHR) [HTA (NIHR155123]. The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care
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Congratulations to @BCIS4Trial for reaching a total 30 randomised participants this week. #LeicesterCTU
4) @easyas_trial has had 9 randomisations 5) @Evocc_Trial had 7 randomisations so far this month. Have a wonderful weekend everyone and stay hydrated. #LeicesterCTU
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4๏ธโฃ How to reconcile STICH and REVIVED? Prognostic impact of medical therapy more powerful now than 20 years ago. Incremental value of CABG over contemporary medical therapy unclear. https://t.co/U4AYYtreXy Need head to head RCT to compare PCI with CABG @BCIS4Trial #STICH3
academic.oup.com
AbstractBackground and Aims. In the Surgical Treatment for Ischaemic Heart Failure Trial Extension Study (STICHES), coronary artery bypass grafting (CABG)
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๐จBREAKING NEWS: 1st participant randomised by the Newcastle upon Tyne Hospitals NHS Foundation Trust - marking the 37th randomisation overall!๐ @NewcastleHosps @bilalbawamia #bcis4
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๐จBREAKING NEWS: 2nd participant randomised by the University Hospitals Dorset NHS Foundation Trust - marking the 36th randomisation overall!๐๐ Massive shoutout to the legends making this important milestone happen! ๐ @DrPeterOKane @UHD_NHS
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๐จBREAKING: Glenfield Hospital on ๐ฅ! 4th participant randomised by the University Hospitals of Leicester NHS Trust - marking the 10th randomisation overall!๐งฎ๐ฅณ Massive shoutout to the legends making this important milestone happen! ๐๐ #BCIS4 @gavinjamesmurph @ALadwiniec
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๐THE RACE IS ON!๐ Which site will be the first to randomise our 10th participant? The showdown starts now - ready, set, randomise! ๐
๐ #BCIS4 #ClinicalTrial @LeicesterCTU @gavinjamesmurph @divaka_perera
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Excited to be part of this study. We have managed to randomise our first patient on the day we opened for recruitment! Thank you @BCIS4Trial, @divaka_perera @gavinjamesmurph @LeicesterCTU @DrMattRyan for getting us to this point rapidly! #BCIS4
๐ข BIG NEWS! The BCIS-4 trial has now opened at its 16th site - Barts Health NHS Trust! ๐ Huge thanks to the amazing team at the St Bartholomewโs Hospital for their commitment to advancing this vital research. Onward and upward! ๐๐ #BCIS4 @NHSBartsHealth @krishnaraj82
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๐ขEXCITING UPDATE! Barts Health NHS Trust has hit the ground running - randomising their 1st participant on the SAME DAY they opened! ๐ฅ This brings us to 9 randomisations study-wide! ๐ Huge cheers to the Barts team for an incredible start!๐๐ #BCIS4 @krishnaraj82 @primustime
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๐ข BIG NEWS! The BCIS-4 trial has now opened at its 16th site - Barts Health NHS Trust! ๐ Huge thanks to the amazing team at the St Bartholomewโs Hospital for their commitment to advancing this vital research. Onward and upward! ๐๐ #BCIS4 @NHSBartsHealth @krishnaraj82
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๐ฏBOOM! Another one in the bag! Guyโs and St Thomasโ NHS Foundation Trust has now randomised their 3rd participant, bringing us to 8 randomisations study-wide! ๐ Huge thanks to the St Thomas' Hospital dream team - youโre unstoppable! @divaka_perera #BCIS4 #GSTT @DrMattRyan
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๐ขWONDERFUL NEWS! University Hospitals of Leicester NHS Trust has now randomised its 3rd participant, bringing us to 7 randomisations study-wide! ๐ฅณ Huge thanks to the Glenfield Hospital team for their hard work and commitment to research!๐๐#BCIS4 @gavinjamesmurph @ALadwiniec
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๐ขMilestone alert! University Hospitals of Leicester NHS Trust has now randomised its 2nd participant, bringing us to 6 randomisations study-wide!๐ Huge thanks to the Glenfield Hospital team for their continued dedication and brilliant work!๐ #BCIS4 @gavinjamesmurph @ALadwiniec
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๐ข GREAT NEWS! The BCIS-4 trial has now opened at its 15th site - welcome to NHS Golden Jubilee! ๐ Big thanks to the Golden Jubilee University Hospital team there for joining us in driving forward this vital research. Onward and upward!๐๐#BCIS4 @JubileeHospital @aadilshaukat34
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๐ขExciting milestone! University Hospitals of Leicester NHS Trust has now randomised its 1st participant, bringing us to 5 randomisations study-wide! ๐ Huge thanks to the Glenfield Hospital team for their hard work and commitment to research! #BCIS4 @gavinjamesmurph @ALadwiniec
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Amazing morning with the @BCIS_uk team as they went to attend Belgrave Library's Chai and Chat with the PPI members.
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๐ข Exciting announcement! The BCIS-4 trial has now expanded to its 14th site at University Hospitals Plymouth NHS Trust! ๐ Huge thanks to the Derriford Hospital team for their commitment to this important research. Onward and upward! ๐๐ #BCIS4 @girishviswa @RDInUHP @UHP_NHS
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๐ข Fantastic news! The BCIS-4 trial has officially expanded to its 13th site at Royal Papworth Hospital NHS Foundation Trust! ๐ A huge thank you to the Royal Papworth Hospital team for their hard work in advancing this vital research. Onward and upward! ๐ #BCIS4 @RoyalPapworth
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Survival better with current medical+ device therapy than STICH-era MT (+/- CABG) if LVEF<35%! โก๏ธ are lessons from all RCTs with a OMT control arm time-limited? โก๏ธ is PCI better than CABG (or vice versa)? These two trials canโt answer this. Await STICH3 trials @BCIS4Trial
How should we interpret STICH in the @REVIVED_BCIS2 era? Did improving OMT between the trials move the goalposts? Can we compare CABG to PCI? The first IPD analysis of randomised data in ischaemic LVSD out today in @ehj_ed. https://t.co/j87W6xFvdL
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๐ข Great news! The BCIS-4 trial has officially expanded to its 12th site at University Hospital Southampton NHS Foundation Trust! ๐ Huge thanks to the amazing team at the Southampton General Hospital for their dedication to this crucial research. Onward and upward! ๐ #BCIS4
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๐ข Exciting news! The BCIS-4 trial has now expanded to its 11th site at Newcastle upon Tyne Hospitals NHS Foundation Trust! ๐ A massive thank you to the incredible team for their dedication to driving this important research forward. Onward and upward! ๐ #BCIS4
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