 
            
              Ariella Coler-Reilly🏳️🌈
            
            @AriellaStudies
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              ⚕️MD PhD Candidate @WUSTLmed 🏳️🌈👩🏼🔬Aging | @UCBerkeley 🐻 | New favorite thing is doing art on @Twitch #SciComm #SciArt 🎨 | 🇺🇸🇯🇵
              
              St Louis, MO
            
            
              
              Joined February 2019
            
            
           It's amazing that you were able to live-tweet all this! Thank you so much @rheum_cat , you're the best!! 🐱❤️ 
          
          
                
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             That's me! I'm Researchers! 😁 Very nice to see this excitement. 🎉 Original paper here: 
          
            
            onlinelibrary.wiley.com
              A meta-analysis of 25 transcriptomic datasets from mammalian tissues revealed 45 genes consistently upregulated or downregulated with age. Orthologs of these genes were functionally evaluated using...
             Big anti aging news Scientists Identify Core "Aging Genes" Shared Across Species. Silencing Them Extends Lifespan Researchers publishing in Aging Cell have pinpointed a set of core genes that drive aging across multiple species, from humans to worms. By analyzing 25 large 
            
                
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             🎉 Congrats to @AriellaStudies on her new publication based on her thesis work! 👏🍾 
           Six Drivers of Aging Identified Among Genes Differentially Expressed With Age  https://t.co/rRiER7ioJM 
            
          
                
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             I guess technically "content availability"? 😅 Glad I procrastinated canceling Hulu so I could do it today specifically ✨ #TeamNetflix
          
          
                
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             We had so much fun recording this week's @RheumMadness podcast to talk about our #RheumMadness scouting report on "Steroid Dose in Lupus Nephritis"! You can find our scouting report here:  https://t.co/QWt4zEwJ6r...  and the first half of the "Full Court Care Champions" (1/2) 
          
                
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             1/ 🚨 NEW #AtTheBedside: Moral Distress Part 2: Strategies & Solutions The FIRST and most important step in addressing moral distress:  ❤️🩹Naming it We must identify what we’re actually feeling 🖥️:  https://t.co/tgbPZA8ZjQ 
          
          
                
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             🚨After 8y and many dead ends- we are excited to clarify how "stable" adipocyte lipolysis is potently activated independent of catecholaminergic signals while being restrained by glucose and insulin. RT and feedback welcome as we work from preprint to pub!  https://t.co/3wO3lUDDfw 
          
          
                
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             [Content Warning: More Feet. 🦶🏼🦶🏼] ... Here is the evolution of my poofy rainbow foot over the last few days. I did order an ankle brace on Amazon and have been using it for the last few days. Not sure it's doing much, but I tried.... 7/x 
          
                
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             Got distracted again (new patient at work!) but to continue... ... I limped around all day, finally went home around 7:30... took off my socks and revealed the ankle... [CONTENT WARNING: feet pics 🦶🏼] My cat and I were both concerned... 6/x 
          
                
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             ... I successfully reached the nurse's station on our floor and asked for help getting some bandages and ice packs, and the nurses very kindly obliged. While the team was occupied with hand-off, I quietly washed up, bandaged my hands, and iced my ankle, which looked okay... 5/x 
          
                
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             ... to be fair, I figured work is literally in a hospital, so it's not a bad choice of location if I develop a need for medical attention. Fortunately, the asphalt dirt blended perfectly into my dark gray heather scrubs, so I didn't look alarming... 4x 
          
                
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             Oops I got distracted and didn't finish the story last night, sorry, my bad. So anyway: After the initial shock of face-planting wore off, I slowly got myself up, retrieved my water bottle, and hobbled out of the street. Then... I went to work.... 3/x 
          
                
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             I am merrily trotting along, excited -- nay, amped -- to seize the day... I step in a pothole, my ankle immediately snaps, and I crumple completely, landing in a motionless, defeated heap, face pressed into the asphalt. My water bottle merrily rolls onwards without me. 2/x 
          
                
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             Okay, it's been a few days, and I'm ready to laugh about it now. ⏮️ Rewind to Tuesday... ⏮️ It is Day 2 of my first clinical clerkship. Call day. Yesterday was just shadowing; today is the REAL first day. It's 6:45am, and I am mere feet from the hospital entrance... 1/x 
          
                
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             Six drivers of aging identified among genes differentially expressed with age @AriellaStudies
             https://t.co/WI885LmW6Y 
          
          
                
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             “Can I still be the good physician, the good person, that I thought of myself as if I continue to work in this situation?” ⤴️ An example of a thought one might have while experiencing moral injury Take a listen ⤵️ 🖥️:  https://t.co/n2OyYICBbx 
          
          
                
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             Very honored to do the art for this wonderful episode on an important issue we do not talk about enough in medicine! Check out the episode below and stay tuned for the sequel Part 2! 👇👇👇 #MedTwitter
          
           1/ 🚨 NEW #AtTheBedside: Moral Distress Part 1: Definitions, Causes & Consequences Time to really name, talk about, and hopefully unpack some of the hidden weight we carry in the practice of medicine ⤵️ 🖥️:  https://t.co/n2OyYICBbx  Sponsor: @Pan_Financial
            
            
                
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             Here is the graphical abstract accompanying our preprint, "Six drivers of aging identified among genes differentially expressed with age." We used worms🪱 to differentiate drivers of aging👵 from passengers and compensatory effects.✨🧬 Please ask questions, the more the merrier! 
           Six drivers of aging identified among genes differentially expressed with age  https://t.co/vhchQhGc5x 
              #biorxiv_genetic
            
          
                
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             Key point for those interested in #longevity research: "Notably, the data do not suggest that the direction of differential expression with age is predictive of the effect on lifespan." 
           Six drivers of aging identified among genes differentially expressed with age  https://t.co/vhchQhGc5x 
              #biorxiv_genetic
            
          
                
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