Check out our work unraveling the molecular basis for the unusual oxygen tolerance of W-Sec-FDH: a redox switch based on an allosteric disulfide bond regulates both high CO2 reductase activity and oxygen tolerance. https://t.co/yToIOU2rj7 #enzymatic #CO2reduction +

🥳🥳🥳 Our study on engineering enzymes to break C–F bonds is now out in @angew_chem! Congrats to the brilliant & dedicated Suzanne Jansen for taking this first step toward the future bioremediation of #PFAS & other contaminating organofluorides! https://t.co/nqHdexP8Rc

📢 📢 📢 !!!Come and join us!! 📢 📢 📢 We are looking for a Postdoctoral Researcher with in-depth experience in next- and third-generation sequencing to help us understand the fitness landscapes of complex biomolecules! Please spread the word :) https://t.co/SgDfiGDkeK

📢📢📢The ML-GUIDE team (@fra_grisoni, @robpollice and myself) are looking for 3 PhD students, passionate about combining the directed evolution of diverse biomolecules with deep learning approaches to develop better (bio)catalysts and drugs! Pls retweet https://t.co/lh3z4RUTeJ

🥳🥳🥳 Early Christmas Present for @fra_grisoni @robpollice and me! @NWOFunding awarded us €2.7 million for our NWO-XL grant "ML-GUIDE – Machine Learning-GUIded Directed Evolution for drug discovery and (bio)catalyst engineering"! Best! Consortium! Ever! https://t.co/AmMMuEAzv1

Beyond thrilled to share that my first PhD paper is out in @JACS_Au! A hunger games-style selection that pits a million biocatalysts against each other, available here: https://t.co/68dlBdwJCs thank you @narf42 for the great supervision!

Our first preprint! Very proud of the excellent work by Vilela-Alves and coworkers, demonstrating at the atomic level how a W/SeCys-Fdh gets inactivated by oxygen. @FCTNOVA @UCIBIO_Research @i4HBio @XTALUCIBIOFCTN1 @NMRFCTNOVA1 @itqbnova @esrfsynchrotron https://t.co/zX05iHhy0g.

If you are looking for a PhD position here it is a great opportunity!

Congratulations Clemens (@narf42) 🥳👏 so well deserved 🎉

🥳🤩🥳I am over the moon that ContiZymes has received an #ERCCoG from the @ERC_Research. I am very grateful to all the people, who helped me preparing the grant. But none of this would have been possible without the outstanding efforts of current and past group members.

It was a pleasure to be focusing on this work for a significant part of my #PhD at @itqbnova. Special thanks to my supervisor @InsCardosoPere1, as well as @cmota_15, @RitaRManuel, and all the authors involved in this work🥳

This mechanism is reversible in vivo and conserved in other FDH from anaerobic bacteria, likely conferring fitness advantage during transient O2 exposure. Additionally, it is a great advantage for the application of this enzyme in biotechnological approaches. +

So happy to see these results finally published in @nchembio! Very proud of the great work by @AnaOlivetree @cmota_15 and coworkers revealing how an FDH can withstand oxygen exposure.👏🍾@itqbnova @FCTNOVA @BIP6_Marseille @LS4FUTURE @i4HBio #CO2 https://t.co/aerp266WCk

🚨🚨New Preprint alert🚨🚨 Ever wondered what would happen if >1 million variants of your favorite biocatalyst compete in hunger-games style selections? Then you are in luck, as the amazing @suzanne__jansen has just done that! https://t.co/fMDmGDaSjv

The last few days were spent surrounded by a great community and full of amazing science #Biotrans2023 It was great to discuss our work (@narf42). It ended in a really nice way #posterprize, I am grateful 😃

To find out more about our work, go and find Rita @AnaOlivetree, who is presenting her fantastic results at #Biotrans2023 on poster number 831!!

The start of new adventures 🤞

I am now a PhD 👩🏻‍🎓🥰 #PhDone #MolecularBiosciences

Great work on the importance of the local environment for enzymatic electrocatalysis by Sam, Vivek and @ReisnerLab 👏👏👏🍾