Ambika Bhagi-Damodaran
@AmbikaBhagi
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Chemist, mom, wife, immigrant, Assistant Professor at University of Minnesota. Metalloenzyme lover.
Minneapolis, MN
Joined October 2018
Awards for top 3 posters - I strongly encourage undergraduate, graduate, and postdocs to apply!!!
Are you a bioinorganic chem researcher attending #ACS Spring 2026? Consider applying to a poster session that I am organizing - "The Jonathan L. Sessler Fellowship for Emerging Leaders in Bioinorganic and Medicinal Inorganic Chemistry – Symposium Honoring Ambika Bhagi-Damodaran"
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Are you a bioinorganic chem researcher attending #ACS Spring 2026? Consider applying to a poster session that I am organizing - "The Jonathan L. Sessler Fellowship for Emerging Leaders in Bioinorganic and Medicinal Inorganic Chemistry – Symposium Honoring Ambika Bhagi-Damodaran"
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Also, we had a ball of a time hosting Sam Catania from Cal Poly and Maria Williams from NYU during the summer. Incredible undergrads! I am so excited about the future of science and chemistry. Here is Sam (presenting a poster) with his mentor Murphi and I.
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Better late than never, congrats to Peter Windsor for successfully defending his PhD!!! Check out Peter's latest work that just came out in ChemBioChem - https://t.co/Zi2Fh2mE3b
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Hi #microbiology twitter, how do you procure an exotic microbe for research purposes? The researcher who last worked on this microbe has retired so academic gifting route cannot be explored.
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A day after #MothersDay, I am excited to announce that I have been promoted to Associate Professor with tenure @UMNChemistry. We did it despite (and with) these two monkeys and a once-in-a-lifetime pandemic. So thankful to my village and hope to pay it forward. I am so lucky!!!
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In case you missed this HOT article from our Emerging Investigators collection ✨ 'Sequential oxidation of l-lysine by a non-heme iron hydroxylase' by @Ambikabhagi, Anoop Damodaran and co. at @UMNChemistry
https://t.co/A7TAihmTvS
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We have emerged, you guys!!! We show sequential oxidation of lysine by a non-heme iron enzyme. The paper was also highlighted in the HOT article collection of Chem Comm.
From our 2025 #EmergingInvestigators collection "Sequential oxidation of l-lysine by a non-heme iron hydroxylase" by Elizabeth Reynolds, Thomas Smith, Anoop Damodaran and @Ambikabhagi Read the full communication here 👇 https://t.co/0RDx0hckEk
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I had such a great time interacting with students and faculty at @IITKanpur. I grew up only 100 miles away from this institute and thanks to @Ritika_Gautam_, was finally able to visit it.
It was a pleasure to host @AmbikaBhagi at the department of chemistry at @IITKanpur. Thanks Ambika for delivering an exceptional talk, engaging with students, and sharing your profound insights into the energy landscape of metalloproteins. @Chemistry_IITK
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Our paper on engineering gas tunnels in an oxygen sensor to reprogram cellular hypoxia signaling is finally online in Angew Chem. Its also been highlighted as a "Hot Article" 🔥🔥🔥🔥 I will write a thread soon but for now enjoy the article!
Gas Tunnel Engineering of Prolyl Hydroxylase Reprograms Hypoxia Signaling in Cells by Yue Chen, Anoop Rama Damodaran, @AmbikaBhagi, and co-workers #OpenAccess
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Also, huge congrats to David Baker whose mind boggling papers I have literally grown up reading. A big win for the computational protein design field.
BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
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A #NobelPrize to Alphafold is the perfect opportunity for me to highlight our paper where crystal structure missed a key detail regarding protein structure but Alphafold predicted it spot on.
Excited that our paper revealing the #ATP binding mechanism of a #redox sensor is out in Biochemistry! Led by Grant Larson, this paper shows how wrong interpretation of a crystal structure can mislead scientists for a decade......Tweetorial below......1/n https://t.co/vLqGMxNuy0
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Alphafold came out in 2020 and a Nobel just 4 years later suggests the power of this discovery and it's implications on research. My lab and so many others in chemistry and biology use AlphaFold all day, everyday.
The 2024 #NobelPrize laureates in chemistry Demis Hassabis and John Jumper have successfully utilised artificial intelligence to predict the structure of almost all known proteins. In 2020, Hassabis and Jumper presented an AI model called AlphaFold2. With its help, they have
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Heck yeah! Proteins rule this world.
BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
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Thanks for the shout-out, Will. And, appreciate your support through these years. I am so lucky to be in the @UMNChemistry family.
Loved hearing my colleague @AmbikaBhagi give her promotion talk. Proud to see how much her lab has accomplished at @UMNCSE @UMNChemistry !
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Uno-dos-tres. Our article on controlled multi-chlorination and bromination by non-heme iron halogenases is out. We show how 2OG eq, catalyst loading & reductant control degree of halogenation. #umnproud of team @hwilson64 @schatterjee_chm @liz_smithwick
https://t.co/WD5sGjq9EL
pubs.acs.org
Geminal, multihalogenated functional groups are widespread in natural products and pharmaceuticals, yet no synthetic methodologies exist that enable selective multihalogenation of unactivated C–H...
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