Alphey Lab
@AlpheyLab
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Arthropod Genetics Group, interested in developing environmentally-friendly tools for insect pest control. All views are our own.
Joined September 2019
Excited to see how UKRI is boosting Engineering Biology across the UK! 🚀 Check out the latest GSE blog post to see how UKRI is fueling innovation in the field. 👇 https://t.co/TiEDcTVeP5
governmentscienceandengineering.blog.gov.uk
Exploring the transformative potential of engineering biology Engineering biology is a transformative technology predicted to add up to $4 trillion per annum to the global economy over the next...
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🧬 Delighted to share our new review on synthetic HEG drives in Ae. aegypti. We examine challenges, propose the CHIROS framework to guide future dev, and discuss paths forward for this vector control strategy. @s_verkuijl @michell56085624 @AlpheyLab
https://t.co/WfRu5wbr8x
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🚀 New paper out in @SciReports! We showed that not all RNA Pol III promoters are created equal—different promoters drive varying homing efficiencies in An. stephensi! 🧬✨ Congrats to the team! 👏 @AEstadea @michell56085624 @joshxdang @PhilipLeftwich
https://t.co/EXVmKfLaHS
nature.com
Scientific Reports - Optimization of SgRNA expression with RNA pol III regulatory elements in Anopheles stephensi
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Had a fantastic time hosting @Jackson_Champer at our lab for a seminar on gene drive! 🎉🧬 Great discussions and loads of inspiration. Thanks for visiting us, and all the best with your future work! 🌟🦟✨ @michell56085624 @joshxdang
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We engineered a CRISPR/Cas9 gene drive in Anopheles stephensi targeting the doublesex gene — aiming to disrupt malaria transmission at its source 🦟🧬 Promising inheritance, some fertility hurdles — but a big step forward! 📖 Read it here:
parasitesandvectors.biomedcentral.com
Background Anopheles stephensi is a competent malaria vector mainly present in southern Asia and the Arabian Peninsula. Since 2012, it has invaded several countries of eastern Africa, creating an...
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🎄 As 2024 wraps up, we’re celebrating the progress we’ve made tackling real-world challenges through biology—together. 🚀 Huge thanks to our amazing team of scientists! 🌟 Merry Christmas & Happy New Year! 🎁🎉 Here’s to solving even bigger challenges in 2025! 💪
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What is #genedrive and how could it help fight mosquito-borne diseases such as #malaria? Hear from experts from the @AlpheyLab @transm0 @imperialcollege and @TargetMalaria in this new @guardiannews piece penned by @taylor_rosie ➡️ https://t.co/Tw2TYHRfTF
@nikiwind
theguardian.com
The technology, which enables a gene to spread itself through a population, might prove a significant tool for disease prevention
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Interested in doing a PhD developing novel tools for the control of vector-borne diseases? Come join us @AlpheyLab @natalieprow13 @michell56085624 at @BiologyatYork. https://t.co/wKnlnXWScL
findaphd.com
PhD Project - MRC DiMeN Doctoral Training Partnership: Engineering mosquitoes to provide no-cold-chain delivery of vaccines at University of York, listed on FindAPhD.com
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Today is #WorldMosquitoDay. The mosquito is considered the deadliest animal in the world, acting as a powerful disease vector. Thank you to @genedrivenet for the opportunity to talk about my work and see the important work of other researchers. ➡️ https://t.co/m58C0LsJs9
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“With #AedesAegypti 🦟becoming more resistant to insecticides, it is critical to develop new strategies to limit the spread of the diseases they transmit.” 🔬🧬 Hear more from Eunice Oluwatobiloba Adedeji @AlpheyLab @BiologyatYork. ➡️ https://t.co/QiG4v8MDzB
#WorldMosquitoDay
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Aedes🦟 are a major global health concern due to their role in spreading disease. This #WorldMosquitoDay, hear from researchers sharing facts about these 🦟, the diseases they carry & novel control tools🔬🧬 ➡️ https://t.co/QiG4v8MDzB
#EndDengue
@PKU1898
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On this #WorldMosquitoDay, we are facing the worst year on record for #dengue fever. @joshxdang @AlpheyLab @BiologyatYork shares his thoughts about this global health threat and tells us why new tools are needed to #EndDengue ➡️ https://t.co/eZWa4gioZS
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If you ever run out of promoters to use for Anopheles stephensi transgenesis, try this out! 😀 Great work getting this out team. @ Joshua Southworth @michell56085624 @AEstadea @Mireia_Larrosa
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The spread of Anopheles Stephensi🦟is threatening progress to #endmalaria in Africa. Last year, @Mireia_Larrosa, @AlpheyLab @UniOfYork presented her research on this vector @ASTMH. Learn more ➡️ https://t.co/FHxF9Guk9e
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ONLY 5 days left to apply!! There are 4 GenerationResearch Masters by research opportunties (2x @BiologyatYork and 2x @ChemistryatYork) Fully funded 1 year projects! Apply below or reach out if you have questions. https://t.co/khmP1ILi6a
generationresearch.ac.uk
Paid technical and research experiences for students
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A peek behind the scenes! The @AlpheyLab group is investigating using genetic methods to control mosquito-borne diseases
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2 fully-funded 4 year #GenRes PhDs @BiologyatYork ! JUST 5 DAYS LEFT ! 1) biochemistry/plant science/biotechnology 2) infection/microbiome/bioinformatics https://t.co/HNRY72Fn7s Looking for enthusiastic and motivated students, especially from underrepresented backgrounds
generationresearch.ac.uk
Paid technical and research experiences for students
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Alphey Lab alumni in GRC Genetic Biocontrol. 😀 Great to have a catch-up with everyone here. @PhilipLeftwich @ArthropodGen @matzenkj @XenWarPrin @s_verkuijl @joshxdang
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