Dr. Alison Paquette
@AlisonPaquette
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I am deciding not to use platforms that are run by people that do not support my values . I hope you’ll follow me on https://t.co/eXZ3DAw0wW or https://t.co/KMW5NRrdiO .
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#JNutr authors studied assn between prenatal vitamin D levels & placental gene expression in a prospective cohort, finding #VitaminD during mid-pregnancy, but not at delivery, assoc'd with placental gene expression at birth" @MarianaParenti @AlisonPaquette
https://t.co/ebB3c47rod
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Looking forward to sharing our work next week with the #ECHO community!
Join us online Wed. 10/9 @ 1 pm ET to see @AlisonPaquette of Seattle Children's Research Institute present our next free, public #ECHODiscovery webinar on the role of the #placenta in the relationship between chemical exposures and #preterm birth: https://t.co/pl7VhCdLC5
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Had such a nice time at IFPA connecting with all my placenta folks ! Great posters by @SamanthaLapehn and @MarianaParenti ! Love these adorable placentas too !
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Great session! Thanks for organizing @KC0nn0r !
Was excited to put together a session on Advances in placental-brain health research @IFPA_Official These amazingly talented speakers made it so worth while! Diversity in questions, approaches, and populations drive innovation, and we saw that in ♠️here in the talks & panel
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Come work with us! We are recruiting a new faculty member with an interest in pediatric environmental health research. @seattlechildren @uwpediatrics Apply here: https://t.co/nvDojzUoSL
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This is an amazing new study that is I think the first I’ve seen to apply mixtures approaches to omics data. Nice job!
Prenatal exposure to #phenols and #phthalates, including #BPA, affects epigenetic programming in offspring, with persistent associations observed into adolescence. This highlights the role of maternal exposure to obesogenic chemicals. https://t.co/M7sc813FjJ
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This work is finally out! Thanks to alll coauthors @JocelynnPearl @_Leena_K @SamanthaLapehn @baloni_priyanka @GeneQueenB @NicoleBushPhD @placresearch and especially @ISBNathanPrice
science.org
A genome-scale network predicts and summarizes gene expression in the placenta, a key tissue for fetal development.
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We built a tool to make this process easier using our harmonized data. We wanted to share this so it might be helpful to others
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We thought that this might answer if one cell line emerged as being closer to human samples on a transcriptomic level, but there is no clear answer. We have learned that the best thing to do is to make an assessment based on your research question
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As we were trying to assess a cell line to use to compare to our human samples, we built a repository of geo datasets, and cleaned and normalized all these datasets so they could be compared.
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Thrilled to share a new tool and accompanying preprint coming out of our group led by @SamanthaLapehn that will help researchers understand what cell line model may be most appropriate to study the placenta
New Preprint- I'm excited to share our new preprint which compares publicly available data of common in vitro models of the human placenta to the transcriptome of bulk placental tissue from the CANDLE and GAPPS cohorts.
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In this cohort study of children with high familial risk of autism spectrum disorder, placental and cord serum metabolism at delivery were highly correlated and associated with neurodevelopmental outcomes. https://t.co/PYwgmDJH8L
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Sharing our work about using placental omics data to understand edcs and preterm birth at #ASRI2024 also can’t wait for this lunch session about reproductive healthcare policy
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Looking forward to sharing our work tomorrow!
Join our #EnvironmentalHealth seminar 5/16 w. Dr. @AlisonPaquette of @seattlechildren: Multi-omic Data Illuminates the Placenta's Role as a Mediator between Prenatal EDC Exposure and Preterm Birth. 12:30-1:20 in UW HSEB, reception to follow, and on Zoom. https://t.co/ukFfzTT8n4
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There's still time to make it to IFPA Montreal 2024! Submit your IFPA late breaking abstracts from May 6th-24th here!
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A historic moment! The first placental toxicology course at SOT. So great to be a part of this amazing team!
Proud to have been a part of the very first @SOToxicology Placental Toxicology Continuing Education Course! Big thank you to co-chairs @almudenaveiga and Dr. Elana Elkin as well as fellow presenters @AlisonPaquette, @bevthescientist and Dr. Phoebe Stapleton! #sot2024
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Looking forward to SOT next week! I will be participating in a continuing education course about placental models. Please join us! It will be a great session #2024SOT
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Important paper highlighting discrepancy between stem cell derived trophoblast organoids compared to trophoblasts.
🚨 NEW PAPER ALERT 🚨 Our latest research in @Dev_Cell dives into assessing primary and stem cell-derived human trophoblast organoids. Find the 🧵 by the first author @MattShannon_Sci below ⬇️ https://t.co/fU1C0iWF38
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Abstract submission is now open! 📝 ⌛ IFPA 2024 will be held in Montreal, Canada from the 2nd - 6th September 2024. Submission deadline is March 22nd, 2024 https://t.co/7AIJZXTayN
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