Alison Biester
@AlisonBiester
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Joined March 2019
Breathing deep: Scientists characterize novel enzymes from deep-sea microbes with a key function in the #ethane degradation process, revealing surprises in the #metabolism of these organisms. Out now @NatureComms
https://t.co/AzEI87mEPk
https://t.co/lo7zdUKcxr
#aechaea #F420
nature.com
Nature Communications - It is generally assumed that CO2 production is coupled to ferredoxin reduction during anaerobic alkane oxidation in archaea. Here, Lemaire et al. use biochemical and...
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This is a beautiful article about a key step in methanogenesis! Congrats, @AlisonBiester, David A. Grahame & @Drennan_Lab "Capturing a methanogenic carbon monoxide dehydrogenase/acetyl-CoA synthase complex via cryogenic electron microscopy" @PNASNews
https://t.co/EMr5sAWkBb
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New Snapshots of Ancient Life: @AlisonBiester (PhD '24), an alum of the @Drennan_Lab and the author of a newly released @PNASNews publication, presents a thoughtful reflection on her research and graduate school experience. https://t.co/F4xAgtK3uk
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Excited to see this work out! Read here about the methanogenic CO dehydrogenase/acetyl-CoA synthase structure: https://t.co/MG3zELBJrG And here about the challenges of obtaining it:
pnas.org
Approximately two-thirds of the estimated one-billion metric tons of methane produced annually by methanogens is derived from the cleavage of aceta...
New Snapshots of Ancient Life: @AlisonBiester (PhD '24), an alum of the @Drennan_Lab and the author of a newly released @PNASNews publication, presents a thoughtful reflection on her research and graduate school experience. https://t.co/F4xAgtK3uk
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Read about an amazing new cryo-ET data processing tool developed by @barrettmpowell from the @jhdavislab! Check out my news article on this work and the publication out now in Nature Methods. https://t.co/cy3517S8YP
https://t.co/y50rVxDQxu
biology.mit.edu
New software allows scientists to model shapeshifting proteins in native cellular environments Cells rely on complex molecular machines composed of protein assemblies to perform essential functions...
From @AlisonBiester reporting on the @jhdavislab, new software allows scientists to model shapeshifting proteins in native cellular environments
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From @AlisonBiester reporting on the @jhdavislab, new software allows scientists to model shapeshifting proteins in native cellular environments
biology.mit.edu
New software allows scientists to model shapeshifting proteins in native cellular environments Cells rely on complex molecular machines composed of protein assemblies to perform essential functions...
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That’s my baymate!!! One million cheers for GPG! 🎉 a wonderful scientist and friend
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Excited to share our group’s work on chemically modifying FeMo-co. Here we report our strategy to selectively enrich one of its seven Fe sites with 57Fe for mechanistic studies of the Mo nitrogenase. Big thanks to Dmitriy, Brian, Dan, and @srisantitham. https://t.co/IKHlxYQJ8s
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The Rees lab is excited to share their work on homocitrate-compromised states of nitrogenase. This work emphasizes the importance of the homocitrate in catalysis & reveals a previously uncharacterized endogenous protein binding partner for nitrogenase.
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At this meeting I will discuss some exciting experiments performed at @SLAClab beamline 9-2, using a very cool technique that was pioneered by SSRL. Please join the meeting to hear more about it!
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And then the two oxidations (right vial) and reaction for reference
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Any ideas why my “irreversible” resazurin reduction reversed (went pink to blue). Shown is reduction to resorufin then dihydroresorufin with 0.03% cysteine
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Could not have done it without the support from @gisele_andree and the @Drennan_Lab overall! I’m happy I get to be part of such a supportive lab.
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I recommended checking out Fig S1 to see the pressurization setup!
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