David Haines EP Fellows Competition continues at #WAFib2025! ⁦@westernAFib⁩ ⁦@nmarrouche⁩ ⁦@AlaAssaf3⁩

Important data from DECAAFII shedding the light on tachycardia mediated Cardiomyopathy in #afib! @S_NarayanMD @shivkumarmd @sumeet724 @netta_doc @PrashSanders @Phiso_de @SamuelSossalla

@AlaAssaf3 shows why all patients with #HF and #AFib need #CMR! Important data from DECAAF at #AHA @nmarrouche @CMahnkopf @Phiso_de @AGEP_DGK @YoungDgk @MekhaelMario @TillAlthoff @netta_doc @shivkumarmd @westernAFib

And thus lower impedance drop*

With obesity projected to rise globally, understanding its direct impact on procedural outcomes is critical. @BidaouiGhassan’s work highlights the need for #personalized ablation strategies to optimize success in obese populations

Despite reduced scar formation and larger LA volumes in obese patients, we found no direct correlation between BMI and AF recurrence (p = .849). This may suggest complex remodeling dynamics in obesity, where factors beyond scar—like metabolic and tissue changes—may play a role

Another significant observation: LA volume was consistently larger in obese patients, both pre- and post-ablation. This might partially explain the role of obesity as a risk factor for AF, with direct effects on the electromechanical functions of the LA

However, @BidaouiGhassan and our team highlight that the effects of obesity on scar formation are independent of its impact on impedance drop, which suggests that additional biophysical or structural effects of obesity

Could this be explained by impedance drop? - Impedance drop is key marker of energy delivery during ablation, and usually associated with durable scar formation - Obesity is known to limit effective energy transfer during ablation and thus lower obesity

Key finding: scar formation continuously decreased with increasing BMI—11.1% in normal-weight patients compared to 6.8% in Class 3 obesity (p < .001)

Obesity is well-known to predispose patients to AF, but this study shows that it also impacts ablation outcomes. A significant inverse correlation between BMI and ablation-induced scar formation was observed (R = -0.135, p < .001)

🎉 Excited to share the impactful work of Dr. Ghassan Bidaoui & team @TulaneTriad @TulaneDDoM, exploring the role of #obesity and #BMI in scar formation post AF #ablation! 🚀 #EPeeps @nmarrouche 🧵🧵

🚨Latest #OpenAccess Article in @JICE_EP Direct-to-Catheter Ablation vs 2nd Line Catheter Ablation for Persistent AF: Effect on Arrhythmia Recurrence, AF Burden, Early LA Remodeling & Quality of Life 🧐📖 https://t.co/2Gn5ure7Bt @HadiiYounes, Besim Ademi, Eli Tsakiris,

#PVI and personalization of treatment ! No one size fits all! Different fibrosis needs different treatment ! #DECAAFII #ESCCongress @shivkumarmd @S_NarayanMD @NazemAkoum @TinaBaykaner @AndreaRussoEP @omwazni @Dr_Santangeli @drluissaenz @netta_doc @chanholim @AlaAssaf3

Live, love, LGE #HRS2024 @nmarrouche @eugenekholmovski

#Proud of the great team @TulaneTriad @TulaneMedicine

@HadiiYounes highlights how female patients are under represented and studied while demonstrating varying ablation outcomes in terms of scar formation, LA volume reduction and AF burden @Phiso_de @HRSonline @TulaneTriad

@HadiiYounes presenting @TulaneTriad data highlighting sex #disparities in access to catheter ablation for #AF and clinical outcomes 🚨A call to action for further research to understand the socioeconomic+ pathophysiological factors driving this gap

@AlaAssaf3 @HanFengGHD innovate yet again with the discovery of a new way to approach atrial myopathy. #entropy provides us the measure of distribution and demonstrates how targeting varying distribution of fibrosis leads to different results from #DECAAFII @nmarrouche

Important #smurden data from #DECAAFII: sustained increased #smurden in the blanking period >8% is #critical in assessing ablation outcomes by @BidaouiGhassan #Epeeps @TulaneTriad @nmarrouche @TulaneDDoM