
Appl Immunohistochem Mol Morphol Journal
@AimmJournal
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Official Journal of @ISIMMweb - EIC: Paul Swanson Account managed by @katcollmd #AIMMjc
#IHCpath
Joined July 2020
Just published! Check out this latest article by @indulkarshreeya @vishalrao1980. 🔬 Molecular subtyping of bladder cancer is vital—but often out of reach.🧪 IHC markers GATA3, KRT20, KRT14, KRT5 used to stratify UCs.⚠️ Dual-negative had poorest survival (25%), luminal best (80%)
Deciphering the Molecular Landscape of Urothelial Carcinoma: Immunohistochemistry-based Subtyping Using 4 Easily Available Antibodies for Cost-effective Stratification
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Just published! Check out this latest article! .🔵 PD-L1 expression showed high concordance between cores and full slides. 🔵 CD8+ T cell and CD68+ macrophage densities varied; cores underrepresented immune infiltrates. @fabiotavora #IHCpath #lungcancer
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🚨 In distal bile duct cancer: .🔹 LATS1/2 expressed in 29.9% ➡️ linked to better prognosis.🔹 YAP (52.2%) & TEAD4 (19.4%) ➡️ tied to advanced stage & worse survival.🔍 Combined LATS1/2⁺ + YAP/TEAD4ˡᵒʷ ➡️ independent favorable prognostic marker.#HippoPathway #LATS1 #YAP #TEAD4
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RT @IHC_guy: I'm delighted to share that the recording of @DrCristinaMagi's @ISIMMweb webinar has been added to our website: .
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Just published! Check out this latest article by @RezaTaha_ @fouad_boulos 👉🏻 HER2 amplification is rare (1.7%) in low-grade, tubule-forming breast cancers with 2+ HER2 IHC; findings suggest ISH may be unnecessary in this subset #breastpath #IHCpath @washu_pathology.
The Value of Routine Reflex In Situ Hybridization Testing in Low-grade Tubule-forming Invasive Breast Cancers With Equivocal HER2 Immunohistochemistry - A Reappraisal of the ASCO/CAP Guidelines
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🧬 Immunohistochemistry in Thymomas.▪️ Bcl-2 and D2-40 positivity varies across thymoma subtypes.▪️ E-cadherin is reduced in invasive tumors.▪️ β-catenin shows subtype-specific expression patterns.📊 66 resected cases analyzed. @byrk_bsr #pathtwitter #pathology #thymoma
Differential Expression Patterns of Bcl-2, D2-40, β-Catenin, and E-Cadherin in Thymomas: Correlation With Clinical Stages and Subtypes
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Telomerase Immunocytochemistry in Lymphocytes From Chronic Lymphocytic Leukemia . ✨hTERT shows stronger nuclear staining in B-CLL cells vs. normal; linked to poor B-CLL prognosis #IHCpath #hemepath @katcollmd @IHC_guy .🔗
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