
Adrien Leger
@AdrienLeger2
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Director of Modified Bases Research at @nanopore. Moving slowly to where the sky is less depressing. https://t.co/U30YEgDbsO
Oxford, England
Joined September 2014
šØ Weāre hiring ! šØ.Join our cutting-edge research team as a molecular biologist at @nanopore HQ in Oxford. Perfect for a fresh PhD or MSc with a couple of yearsā experience. Work at the interface of chemistry, molecular/synthetic biology and AI. š
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RT @Stoibs11: More details on new RNA modified bases detectable with @nanopore sequencing. #NanoporeConf
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RT @Stoibs11: Dorado 1.0 šrelease with new RNA modified base models for 2āOme as well as improvement of all DNA and RNA modified base modelā¦.
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RT @Daniela_Bezdan: Tweet 1/2.WOWā2āO-methylation detection in direct RNA-seq is here! A breakthrough for RNA therapeutics, viral evasion,ā¦.
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RT @bioinformer: Who has DNA methylation on ~5,000 microbes sequenced w/@nanopore? We do! . Whoās working hard on getting this data out befā¦.
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RT @iiSeymour: Dorado is 1.0! š. This London Calling release updates our DNA and RNA models to v5.2 with a new suite of mod models that areā¦.
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RT @nathanbaggers: Excited about @nanopore's collaboration with @uk_biobank to create the first comprehensive epigenetic map of the human gā¦.
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RT @Libby_Snell_: I am absolutely thrilled to be back in Kanazawa, Japan (a fave!), for the #tRNA2024 conference! It was my pleasure to preā¦.
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It's Christmas in advance with a very special @nanopore #opendata release ! š
.Today we are releasing our 5mC 5hmC and 6mA DNA mod synthetic control datasets with each mods in all possible 5 mers contexts. All nicely wrapped in a comprehensive validation blog post.š.
New blog: Modified Base Best Practices & Benchmarking for @nanopore 𧬠sequencing Includes:. * Raw POD5 files for synthetic ground truth strands.* Modified base calling best practices.* Modkit recommendations. Check it out: #methylation #bioinformatics.
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RT @Stoibs11: New blog: Modified Base Best Practices & Benchmarking for @nanopore 𧬠sequencing Includes:. * Raw POD5 files for synthetic grā¦.
epi2me.nanoporetech.com
Modified bases, including methylation, regulate many biological processes - from eukaryotic geneā¦
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RT @slavov_n: The epitranscriptome formed by the growing number of modifications occurring within mRNA transcripts.
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RT @RosemaryDokos: Low coverage (5x) @nanopore data vs methylation arrays delivers far more data. Great talk by the wasatch team at #ashg20ā¦.
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RT @ewanbirney: Some perspective here - like protein modification - phosphorylation, acteylationn etc - and DNA modification - 5mC, 5hmC anā¦.
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RT @ewanbirney: When we look at the kmers around the sites, we see enrichment in the DRACH motif and the known m5C motifs, along with novelā¦.
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